Contents. List of Contributors. Preface (G. Heppner). Differentiation and Breast Cancer Development (J. Russo and I.H. Russo). Growth Factor Signal Transduction and Hormone Independence in Breast Cancer (D.L. Miller and F.G. Kern). Biology of High Risk Benign Breast Lesions (F.R. Miller). Estrogen Receptor Variants in Early Breast Disease and Breast Cancer Progression (A.V. Lee, S. Oesterreich, and S.Q.W. Fuqua). Biological Basis of Genetic Predisposition to Breast Cancer (S.H. Dairkee and H.S. Smith*). The Clinicopathologic Significance of Genetic Instability in Breast Carcinoma Progression (D.W. Visscher and S.M. Wykes). The Histopathology of Transgenes and Knockouts in the Mammary Gland (R.D. Cardiff and R.J. Munn). Immune Facilitation of Breast Cancer (T.H.M. Stewart and G.H. Heppner). A History of Cancer of the Male Breast (P.J. Dawson). Index.