Brain Mechanisms in Mental Retardation - 1st Edition - ISBN: 9780121390501, 9781483281810

Brain Mechanisms in Mental Retardation

1st Edition

Editors: Nathaniel A. Buchwald Mary A. B. Brazier
eBook ISBN: 9781483281810
Imprint: Academic Press
Published Date: 1st January 1975
Page Count: 558
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Series on Mental Retardation held in Oxnard, California, in January 1974. This book compiles research on neurobiological findings which might lead to an understanding of the basic processes underlying the phenomena of mental deficiency and related aspects of human development. The topics discussed include the timing of major ontogenetic events in the visual cortex of the rhesus monkey; neuronal sprouting after hippocampal lesions; synaptic and dendritic development and mental defect; and CNS maturation and behavioral development. The neuronal control of neurochemical processes in the basal ganglia; nigrostriatal projections and the “dopamine receptor”; and effects of caudate nuclei removal in cats are also deliberated. This text likewise covers the effects of caudate nuclei removal versus frontal cortex lesions in kittens and role of biochemistry in research on mental retardation This publication is beneficial to medical practitioners and students concerned with mental retardation.

Table of Contents

List of Contributors and Participants Foreword Welcoming Remarks Part I Development of Neuronal Functions 1 Timing of Major Ontogenetic Events in the Visual Cortex of the Rhesus Monkey References 2 Effects of Interference with Cerebellar Maturation on the Development of Locomotion. An Experimental Model of Neurobehavioral Retardation References 3 Neuronal Sprouting after Hippocampal Lesions References 4 Physiological Properties of Vertebrate Nerve Cells in Tissue Culture References 4A Discussion: Biochemical Studies in Various Culture Systems of Neural Tissues References 5 Synaptic and Dendritic Development and Mental Defect References 6 Normal and Aberrant Neuronal Development in the Cerebral Cortex of Human Fetus and Young Infant References 6A Discussion: CNS Maturation and Behavioral Development References 6B Discussion: Development of Postsynaptic Potentials Recorded from Immature Neurons in Kitten Visual Cortex References Part II Role of the Basal Ganglia in Normal and Abnormal Development 7 Neurophysiological and Anatomical Interrelationships of the Basal Ganglia References 8 Neuronal Control of Neurochemical Processes in the Basal Ganglia References 8A Discussion: L-Dopa-Induced Improvement of Conditioned Response Inhibition References 8B Discussion: Acetylcholine and the Caudate References 9 Dopamine-Containing Neurons of the Substantia Nigra and Their Terminals in the Neostriatum References 9A Discussion: Nigrostriatal Projections and the "Dopamine Receptor" References 10 Effects of Caudate Nuclei Removal in Cats. Comparison with Effects of Frontal Cortex Ablation References Part III Behavioral Plasticity during Development 11 Brainstem Substrates of Sensory Information Processin


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© Academic Press 1975
Academic Press
eBook ISBN:

About the Editor

Nathaniel A. Buchwald

Mary A. B. Brazier

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