Botulinum Toxin - 1st Edition - ISBN: 9781416049289, 9781437711196

Botulinum Toxin

1st Edition

Therapeutic Clinical Practice and Science, Expert Consult - Online and Print

Authors: Joseph Jankovic Alberto Albanese M. Zouhair Atassi J. Dolly Mark Hallett Nathaniel Mayer
Hardcover ISBN: 9781416049289
eBook ISBN: 9781437711196
Imprint: Saunders
Published Date: 9th February 2009
Page Count: 512

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The new, therapeutically-focused Botulinum Toxin presents comprehensive, cross-disciplinary guidance on current practices, covering more than 100 non-cosmetic conditions that occur in neurology, physical medicine and rehabilitation, pain medicine, ophthalmology, gastroenterology, urology, orthopedics, and surgery. International contributors review the current understanding of the biology and cellular mechanisms along with relevant research so you can easily apply them to the pathophysiology of the numerous disorders that botulinum toxin is used to treat—such as botulinum toxin applications for the treatment of cranial-cervical dystonias, motor disorders in cerebral palsy, bruxism and temporomandibular disorders, headache, overactive bladder, chronic pelvic pain syndromes, arthritis joint pain, and wound healing. With discussions of the latest in approved treatment practices as well as new and emerging uses, you’ll get in-depth management guidance on the application of the toxin.

Key Features

  • Provides clinical applications of botulinum toxin for over 100 disorders for immediate access and easy reference during practice and treatment.
  • Covers a broad array of hot topics, including botulinum toxin applications for the treatment of cranial-cervical dystonias, motor disorders in cerebral palsy, bruxism and temporomandibular disorders, headache, overactive bladder, chronic pelvic pain syndromes, arthritis joint pain, and wound healing.
  • Focuses on approved uses with expert advice on thoroughly tested applications but also discusses new and emerging applications to expose you to additional treatment options.
  • Presents the most comprehensive and up-to-date material available so you get all the information you need from this one resource.
  • Offers the cross-disciplinary guidance of the best world-class expertise through an authoritative, international group of authors who demonstrate the applications of botulinum toxin across various specialties.

Table of Contents

  1. Multiple Steps in the Blockade of Exocytosis by Botulinum Neurotoxins, Dolly, J. Oliver, Jianghui Meng, Jiafu Wang, Gary W. Lawrence, MacDara Bodeker, Tomas H. Zurawski, and Astrid Sasse, Editor: M. Zouhair Atassi

    2. Molecular Structures and Functional Relationships of Botulinum Neurotoxins, Subramanyam Swaminathan, Editor: J. Oliver Dolly

    3. Botulinum Neurotoxin – a Modular Nanomachine, Audrey Fischer, Lilia Koriazova, Myrta Oblatt-Montal and Mauricio Montal, Editor: J. Oliver Dolly

    4. Interactions Between Botulinum Neurotoxins and Synaptic Vesicle Proteins, Axel T. Brunger, Rongsheng Jin, and Mark A. Breidenbach, Editor: J. Oliver Dolly

    5. Immune Recognition of Botulinum Neurotoxins A and B and Molecular Elucidation of Immune Protection Against the Toxins, M. Zouhair Atassi, Editor: J. Oliver Dolly

    6. Biology and Clinical Pharmacology of Botulinum Neurotoxin type C and Other Non-A/Non-B Botulinum Neurotoxins, Roberto Eleopra, Cesare Montecucco, Editor: M. Zouhair Atassi

    7. Effects of Botulinum Toxin on Central Nervous Function, Carlo Trompetto, Giovanni Abbruzzese, Alfredo Berardelli, Antonio Suppa, Editor: Mark Hallett

    8. Botulinum Neurotoxin Treatment of Cranial-Cervical Dystonia, Christopher Kenney, Joseph Jankovic, Editor: Alberto Albanese

    9. Botulinum Neurotoxin Treatment of Limb and Occupational Dystonias, Barbara Illowsky Karp, Editor: Joseph Jankovic

    10. Botulinum Neurotoxin in Tremors, Tics, Hemifacial Spasm, and Spasmodic Dysphonia, Anna Rita Bentivoglio, Alfonso Fasano, Alberto Albanese, Editor: Joseph Jankovic

    11. Upper Limb Skin and Musculoskeletal Consequences of the Upper Motor Neuron Syndrome, Nathaniel Mayer, Alberto Esquenazi, Editor: Mark Hallett

    12. Clinical Trials of Botulinum Neurotoxin in Adult Spasticity: Meta-Analysis of Outcomes, Antonio Elia, Graziella Filippine, Alberto Albanese, Editor: Mark Hallett

    13. Biological & Mechanical Pathologies in Spastic Skeletal Muscle: The Functional Implications of Therapeutic Neurotoxins, Samuel Ward, Richard Lieber, Editor: Nathaniel Mayer

    14. Treatment of Motor Disorders in Cerebral Palsy With Botulinum Neurotoxin, Jane Leonard, H. Kerr Graham, Editor: Nathaniel Mayer

    15. Clinical Experience & Recent Advances in the Management of Gait Disorders with Botulinum Neurotoxin, Alberto Esquenazi, Nathaniel Mayer, Editor: Mark Hallett

    16. Treatment of Ormandibular Dystonia, Bruxism and Temporomandibular Disorders with Botulinum Toxin, Nwangmegha Young, Andrew Blitzer, Editor: Joseph Jankovic

    17. Botulinum Toxin in Headache Management, Stephen Silberstein, Editor: Alberto Albanese

    18. Botulinum Toxin Therapy in Gastrointestinal Disorders, Rajasekhara Mummadi, Pankaj J. Pasricha, Editor: Alberto Albanese

    19. Mechanism of Action of Botulinum Neurotoxin in the Bladder, Michael Chancellor, George Somogyi, Christopher P. Smith, Editor: Alberto Albanese

    20. Botulinum Neurotoxin in Overactive Bladder, Brigitte Schurch, Dennis Dykstra, Editor: Alberto Albanese

    21. Botulinum Toxin in the Treatment of Chronic Pelvic Pain Syndromes, Phillip P. Smith, Christopher Smith, Editor: Nathaniel Mayer

    22. Application of Botulinum Neurotoxin in the Prostate, Yao Chi Chuang, Michael B. Chancellor, Editor: Alberto Albanese

    23. Clinical Application of Botulinum Neurotoxin in the Treatment of Myofascial Pain Syndromes, Martin Childers, Editor: Nathaniel Mayer

    24. Intra-Articular Botulinum Neurotoxin for Arthritis Joint Pain, Maren Lawson Mahowald, Hollis E Krug, Jasvinder A Singh, Dennis Dykstra, Editor: Nathaniel Mayer

    25. Botulinum Neurotoxin in the Management of Hyperhidrosis and Other Hypersecretory Disorders, Dee Anna Glaser, Markus Naumann, Editor: Alberto Albanese

    26. Botulinum Neurotoxin for Dermatologic and Cosmetic Disorders, Dee Anna Glaser, Editor: Nathaniel Mayer

    27. The Role of Botulinum Neurotoxin in Wound Healing, Holger G. Gassner, David A. Sherris, Kris S. Moe, Oren Friedman, Editor: Nathaniel Mayer

    28. Understanding Botulinum Neurotoxin Mechanism of Action and Structure to Enhance Therapeutics and Improve Care, Keith A Foster, Emily J. Adams and Duncan F. Rogers, Editor: M. Zouhair Atassi

    29. Unmet Needs and Challenges in the Therapeutic Use of Botulinum Neurotoxins, David Simpson, Yuen T. So, Editor: Joseph Jankovic

    30. Potential New Therapeutic Indications of Botulinum Neurotoxins, Mark Hallett, Editor: Joseph Jankovic

    31. Botulism Vaccines and the Immune Response, Leonard Smith, Janice Rusnak, Editor: M. Zouhair Atassi

    32. Properties of Pharmaceutical Products of Botulinum Neurotoxins, Hans Bigalke, Editor: J. Oliver Dolly

    33. Comparative Clinical trials Of Botulinum Toxins, Dirk Dressler, Cindy Comella, Editor: Alberto Albanese

    34. Tetanus Toxin, Paul Fishman, Editor: Mark Hallett

    35. Bungarotoxins, Florenta Aura Kullmann, William C. de Groat, Debra Elaine Artim, Editor: Mark Hallett

    36. Biology and Pharmacology of Conotoxins, Russell W. Teichert, Elsie C. Jimenez, Baldomero M. Olivera, Editor: Mark Hallett

    37. Therapeutic Applications of Conotoxins, Michael F. Saulino, Editor: J. Oliver Dolly

    38. Spider and Wasp Neurotoxins, Wagner F. dos Santos, Editor: J. Oliver Dolly


No. of pages:
© Saunders 2009
9th February 2009
Hardcover ISBN:
eBook ISBN:

About the Authors

Joseph Jankovic

Affiliations and Expertise

Professor Neurology, Distinguished Chair in Movement Disorders, Director, Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, TX

Alberto Albanese

M. Zouhair Atassi

Affiliations and Expertise

Robert A. Welch Chair of Chemistry, Professor of Biochemistry and Molecular Biology, Professor of Immunology, Baylor College of Medicine, Houston, TX

J. Dolly

Mark Hallett

Affiliations and Expertise

School of Medicine and Health Sciences, George Washington University, Washington, DC, USA

Nathaniel Mayer