Most recent volume

Volume 22. Molecular Anatomy of Cellular Systems

Published: 20th August 2002 Editors: I. Endo I. Yamaguchi T. Kudo H. Osada T. Shibata
In this book, the progress during the last ten years is reviewed and future plans outlined to realize and establish the concept of design in the biological sciences.

Design is a leading concept as well as the principal motivation for the creation of artificial systems. A successful design generally requires that the structures and functions of the elements that constitute the system as well as the principles that determine how the elements cooperate together to create function be fully understood. These requirements have not been satisfied within the fields of biotechnology and medicine. Compared to the recent emergence of artificial systems, living organisms acquired their present day structures and functions through evolution over three to four billion years. Despite the fact that the design of living organisms is recorded in the DNA sequence, our understanding of the structures and functions of the elements that constitute living organisms is very limited.

To fulfill the requirements, the following approaches were initiated under a ten-year project entitled "Biodesign Research". Firstly, we tried to isolate and characterize the functional elements that constitute the organelles of various organisms. Secondly, we tried to reconstitute systems that reproduce biological functions in vitro from individual elements in order to understand how the elements cooperate together to yield a function. Thirdly, we attempted to resolve biological structures at various resolutions ranging from the atomic to the cellular level to further our knowledge about the fundamental principles that various functions at the molecular level and to design artificial systems.

Additional volumes

Volume 21. Biotechnology in the Pulp and Paper Industry

Published: 12th June 2002 Editors: L. Viikari R. Lantto

Volume 20. Biotechnology Organizations in Action

Published: 6th March 2002 Author: J. Norus

Volume 19. Trends in High Pressure Bioscience and Biotechnology

Published: 21st January 2002 Editor: R. Hayashi

Volume 18. Molecular Breeding of Woody Plants

Published: 30th November 2001 Editors: Noriyuki Morohoshi Atsushi Komamine

Volume 17. Food Biotechnology

Published: 19th July 2000 Editors: S. Bielecki J. Polak J. Tramper

Volume 16. Bioseparation Engineering

Published: 17th March 2000 Editors: I. Endo T. Nagamune S. Katoh T. Yonemoto

Volume 15. Stability and Stabilization of Biocatalysts

Published: 10th November 1998 Editor: A. Ballesteros Authors: F.J. Plou J.L. Iborra P.J. Halling

Volume 14. Pectins and Pectinases

Published: 6th December 1996 Editors: J. Visser A.G.J. Voragen

Volume 13. High Pressure Bioscience and Biotechnology

Published: 9th December 1996 Editors: Claude Balny R. Hayashi

Volume 12. Enzymes for Carbohydrate Engineering

Published: 6th August 1996 Editors: K.-H. Park J.F. Robyt Y-D. Choi

Volume 11. Immobilized Cells: Basics and Applications

Published: 21st March 1996 Editors: R.M. Buitelaar C. Bucke J. Tramper R.H. Wijffels

Volume 10. Carbohydrate Bioengineering

Published: 8th December 1995 Editors: S.B. Petersen B. Svensson S. Pedersen

Volume 8. Biocatalysis in Non-Conventional Media

Published: 4th September 1992 Editors: M.H. Vermuë H.H. Beeftink U. van Stockar J. Tramper

Volume 4. Industrial Proteins in Perspective

Published: 16th May 2003 Editors: W.Y. Aalbersberg R.J. Hamer P. Jasperse Jo-Celene de Jongh C.G. de Kruif P. Walstra F.A. de Wolf