Series: Handbook of Behavioral Neuroscience

The Handbook of Behavioral Neuroscience series covers compelling, topical subjects in behavioral neuroscience. Each volume is a comprehensive guide to the latest research of interest to researchers in the behavioral sciences. Joseph P. Huston, Director, Center for Bahavioral Neuroscience, Heinrich-Heine-Universität Düsseldorf

Most recent volume

Volume 27. Translational Medicine in CNS Drug Development

Published: 1st April 2018 Editors: George Nomikos

Translational Medicine in CNS Drug Development is the first book of its kind to offer a comprehensive overview of the latest developments in translational medicine and biomarker techniques to aid researchers in the development of new drugs targeting disorders of the central nervous system. Despite increases in the number of individuals suffering from CNS-related disorders, development and approval of drugs to effectively treat them have been hampered by inefficiencies in advancing compounds from preclinical discovery to the clinic. However, in the past decades, game-changing strides have been made in our understanding of the pathophysiology of CNS disorders and the relationship of drug exposure in plasma and the CNS to pharmcodynamic measures in both animals and humans. Significantly, major progress has been made in neuroimaging, neurochemical, neurophysiological, and pharmacogenetic/pharmacogenomics biomarker tools that can be used for monitoring diagnosis and progression of diseases, as well as monitoring drug responses by showing central exposure, target engagement, functional responses, and patient enrichment in clinical trials.

With extensive coverage of all aspects of biomarkers and personalized medicine, and numerous chapters devoted to the best strategies for developing drugs that target specific disorders, Translational Medicine in CNS Drug Development is an essential reference for researchers in neuroscience and pharmacology who need the most up-to-date techniques for successful development of drugs to treat central nervous system disorders.

Additional volumes

Volume 26. Handbook of Ultrasonic Vocalization

Published: 1st January 2018 Editors: Stefan Brudzynski

Volume 25. A Researcher's Guide to Rodent Behavior

Published: 1st January 2018 Editors: Robert Deacon

Volume 24. Handbook of Basal Ganglia Structure and Function

Published: 17th October 2016

Volume 23. Modeling the Psychopathological Dimensions of Schizophrenia

Published: 16th November 2015 Editors: Mikhail Pletnikov John Waddington

Volume 22. Invertebrate Learning and Memory

Published: 1st June 2013 Editors: Randolf Menzel Paul Benjamin

Volume 22. Companion site for Invertebrate Learning and Memory

Editors: Randolf Menzel Paul Benjamin

Volume 21. Handbook of the Behavioral Neurobiology of Serotonin

Published: 2nd December 2009 Editors: Christian Muller Barry Jacobs

Volume 19. Handbook of Mammalian Vocalization

Published: 26th October 2009 Editors: Stefan Brudzynski

Volume 18. Handbook of Episodic Memory

Published: 20th September 2008 Editors: Ekrem Dere Alexander Easton Lynn Nadel Joe Huston

Volume 17. Handbook of Anxiety and Fear

Published: 17th March 2008 Editors: D. Caroline Blanchard D. Caroline Blanchard Guy Griebel David Nutt

Volume 16. Handbook of Microdialysis

Published: 9th January 2007