Series: Advances in Molecular and Cellular Endocrinology

Historically the field of endocrine research has always been at the forefront of scientific endeavors. The investigators of these important breakthroughs in research have been rewarded by numerous Nobel awards. In the field of diabetes alone, Nobel prizes have been awarded to researchers who discovered insulin, characterized the protein and invented radioimmunoassays using insulin as a paradigm. Not surprisingly, biomedical researchers have always been attracted by the endocrine system and other similar systems of intercellular communication. Over the past two decades, endocrine research has developed rapidly and adapted modern molecular and cellular biology techniques for its specific use. These changes have allowed researchers in the field to maintain their edge. Thus, endocrine disease-related genes have been characterized and mutations in these genes have helped explain common and less common endocrine disorders. Our understanding of the regulation of gene expression has been greatly enhanced by molecular techniques. In an attempt to bring investigators up to date with the recent advances in this exploding field we have decided to publish a series entitled Advances in Molecular and Cellular Endocrinology. Internationally famous investigators have agreed to participate and their contributions are appreciated.

Book Series: New Transcription Factors and Their Role in Diabetes and Therapy

Most recent volume


Volume 5. New Transcription Factors and Their Role in Diabetes and Therapy

Published: 10th August 2006 Editor: Jacob Friedman
1. PPARs as therapeutic targets for treating diabetes and insulin resistance 2. Genetic regulators of human obesity and diabetes 3. NF-kb, insulin resistance and the actions of salicylates 4. Wnt signaling and C/EBPs role in adipogenesis 5. Regulation of hepatic gluconeogenesis C/EPBs 6. Forkhead proteins and regulation of hepatic gene expression 7. Control of mitochondrial biogenesis through PGC-1 8. Regulation of PGC-1 in humans in insulin resistance and diabetes: Functional implications 9. FOXC2 controls resistance to obesity and Type II diabetes 10. SREB-1C regulation of nutrient homeostasis and lipid accumulation 11. GATA proteins as molecular gatekeeprs of the adipocyte 12. Diabetes regulation of gene expression by CREB 13. Molecular etiologies of MODY and other early-onset forms of diabetes 14. Liver X receptors as potential drug targets for Diabetes and its disorders 15. The potential therapeutic use of PPAR beta/delta agonists in lipid and glucose homeostasis 16. Influences of new PPAR insulin sensitizers on the metabolic syndrome in Rhesus Monkeys 17. PPARgamma and metabolism: Insights from the study of human genetic variants

Additional volumes


Volume 4. Thyroid Neoplasms

Published: 8th April 2005 Series Editor: Boris Draznin

Volume 2. Advances in Molecular and Cellular Endocrinology

Published: 23rd January 1998 Editor: D. LeRoith

Volume 1. Advances in Molecular and Cellular Endocrinology

Published: 25th March 1997 Editor: D. LeRoith