Blood Group Substances

Preface1. Introduction. The Human Blood Group Factors The ABO System Other Blood Group Systems Isoimmunization and the Discovery of Blood Group Systems Isoimmunization in Other Animals Panagglutinable Erythrocytes Erythrocyte Mosaicism Actively Acquired Tolerance to Foreign Cells Autoantibody Formation and Hemolytic Anemia Genetic Basis of Blood Grouping References2. Methods and Reagents Used in Testing for Blood Group Antibodies and Antigens Hemagglutination Tests for "Blocking" Antibody Potency of Antisera for Blood Grouping Effects of Temperature on Hemagglutination Assay for Blood Group Substances in Solution Estimation of Antibody Nitrogen Content of Antisera Estimation of Blood Group Substances Estimation of the Degree of Precipitability of an Antigen by Excess Antibody Elution of Antibodies from Erythrocytes Preparation of Human Antisera to the Various Blood Group Substances in Humans Antisera for the Coombs Test Miscellaneous Sera and Materials Reacting with Blood Group Antigens Enzymes Splitting Blood Group Substances Effect of Periodate on'Blood Group Substances References3. Sources of Blood Group Substances A, B, O (H), and Lea Substances Other Blood Group Substances References4. Purification of Blood Group Substances Substances from Erythrocytes Blood Group A, B, O (H), and Lea Substances from Glandular Tissues and from Secretions Recommended Procedures for the Purification of Blood Group A, B, O (H), or Lea Substances from Tissues or Secretions A and O Substances from Hog Gastric Mucosa A, B, O (H), and Lea Substances from Human Saliva or Amniotic Fluid A, B, and Inactive Substances from Horse Gastric Mucosa A, B, O (H), and Lea Substances from Pseudomucinous Ovarian Cyst Fluids Blood Group Substances from Meconium References5. Chemical Composition and Properties of the Blood Group A, B, O (H) and Lea Preparations References6. Chemical and Immunochemical Characterization of the Blood Group Substances-Evidence of Purity Chemical Characterization Immunochemical Characterization References7. Immunochemical Similarities and Differences among Blood Group Substances from Various Species Differences by Hemagglutination Inhibition Differences by Quantitative Precipitin Tests Cross Reactivity with Type XIV Antipneumococcal Serum Antigenicity Differences Relation to the J Factor and the R and r Factors of Sheep References8. Some Features of the Structure of the Blood Group A, B, O (H) and Lea Substances Structural Changes Produced by Mild Acid Hydrolysis Structural Changes Produced by Sodium Carbonate Structural Changes Produced by Enzymes Splitting Blood Group Substances Structural Information Obtained from Studies on Inhibition with Simple Sugars of Hemagglutination by Plant Agglutinins and Antibodies Structural Information from Studies on the Inhibition of Blood Group Splitting Enzymes by Simple Sugars Periodate Oxidation References9. Antibodies to Blood Group Substances and their Biological Effects Saline Agglutinating and Blocking Antibodies "Linked" Anti-A and Anti-B Purification and Concentration of Blood Group Antibodies Properties of Blood Group Antibodies Passage of Antibodies through the Placenta Thermodynamic Studies on Anti-A and Anti-B Studies with Antibodies Labeled with Radioactive Isotopes Miscellaneous Applications of Blocking Antibody References10. Biological Effects and Uses of Blood Group Substances-Materials of Similar Chemical Composition Effects of Injection of A and B Substances Blood Group Substances and their Relation to Intrinsic Factor Relationship of Blood Group Substances to the Virulence-Enhancing Factors in Hog Gastric Mucosa Relation of Blood Group Substances to Materials Inhibiting the Action of Various Viruses Miscellaneous Activities Reported to Be Associated with Blood Group Substances; Substances with Constituents Present in Blood Group Substances ReferencesIndex