Blood and Tissue Antigens - 1st Edition - ISBN: 9780120570508, 9781483282435

Blood and Tissue Antigens

1st Edition

International Symposium on Blood and Tissue Antigens Held at the University of Michigan Medical Center, September 17-19, 1969

Editors: David Aminoff
eBook ISBN: 9781483282435
Imprint: Academic Press
Published Date: 1st January 1970
Page Count: 554
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Description

Blood and Tissue Antigens documents the proceedings of the International Symposium on Blood and Tissue Antigens held in Ann Arbor, Michigan on September 17-19, 1969. This book focuses on the immunogenetic and biochemical aspects of the blood and tissue antigens. The topics discussed include the genetics of blood groups; blood groups and serum phosphatase; immunogenetics of the mouse H-2 system; and glycolipids as membrane antigens. The carbohydrate composition of epithelial mucins; glycolipids in SV40 and polyoma virus transformed mouse cell lines; and metabolic variations of serum proteins and enzymes are also elaborated. This text likewise covers the action of glycosidases on erythrocytes; blood group specific oligosaccharides in urine; biosynthesis of submaxillary mucins; and genes, glycosyltransferases, and blood types. This publication is a good source for students and individuals researching on blood and tissue antigens.

Table of Contents


Participants

Preface

Biographical Sketch

Opening Remarks

General Introduction

I. Immunogenetics

Genetics of Blood Groups

Discussion

The Blood Group Polymorphisms: Why Are They There?

Discussion

Blood Groups and Sodium, Potassium Stimulated ATPase

Discussion

Blood Groups and Serum Phosphatase

Discussion

II. Cellular Antigens

Immunogenetics of the Mouse H-2 System

Transplantation Antigens: Some Features of Mouse H-2 Molecules and Their Relevance to HL-A in Man

Discussion

Glycoprotein Antigens Isolated from RBC

Discussion

Immunochemistry of Cattle Blood Group J Hapten

Discussion

Glycolipids as Membrane Antigens

Discussion

Studies on the Chemical Structure of Blood Group A Specific Glycolipids from Human Erythrocytes

Discussion

III. Water-Soluble Antigens

The Carbohydrate Moiety of the Water-Soluble Human A, B, H, Le a, and Le b Substances

Discussion

Nature of the Protein Core of Bovine, Ovine, and Porcine Submaxillary Mucins and Its Implications for Protein Synthesis

Discussion

Ultrastructural Observations of Mucous Secreting Cells in Bovine Submandibular Glands

Carbohydrate Composition of Epithelial Mucins

Discussion

Human Sources of Blood Group Substances

Discussion

Importance of Human Red Cell Surface Structures in Reactions between Man and Microbes

Discussion

Topochemical Arrangement of Neuraminic Acid Containing Receptors within the Cell Membrane

Discussion

Biophysical Characteristics of the Blood Group Substances

Discussion

IV. Presentation of Abstracts

Structural Aspects of Human Blood-Group M and N Specificity

Discussion

Glycolipids in SV40 and Polyoma Virus Transformed Mouse Cell Lines

Discussion

Action of Iso-Immune Anti-M and Anti-L on Active Potassium Transport in HK and LK Sheep Red Cells

Discussion

Antigenicity of Red Cell Membrane Proteins

Discussion

Study by Immunofluorescence of the Anatomy of Le(a) and (b) Substances in Human Fetuses

LW Factor

Discussion

Metabolic Variations of Serum Proteins and Enzymes

Intracellular Localization of Glycosyltransferases in a Golgi-Rich Fraction from Rat Liver

Discussion

V. Enzymatic Degradation and Metabolism of Blood Group Substances

Some Properties of Sialoglycopeptides Released from Human Erythrocytes by Treatment with Proteinases

Discussion

Glycosidases and Serological Changes in Blood Group Substances

Discussion

Stereospecificity of Glycosidases That Act on Blood Group Substances

Discussion

Action of Glycosidases on Erythrocytes

Discussion

Blood Group Specific Oligosaccharides in Urine

Discussion

VI. Biosynthesis of the Blood Group Substances

Biosynthesis of Blood Group Substances, Current Concepts, and Results

Discussion

Biosynthesis of Submaxillary Mucins

Discussion

Biosynthesis of Ovine Submaxillary Mucoproteins at the Cellular and Subcellular Level

Discussion

Genes, Glycosyltransferases, and Blood Types

Discussion

Summing up

Subject Index


Details

No. of pages:
554
Language:
English
Copyright:
© Academic Press 1970
Published:
Imprint:
Academic Press
eBook ISBN:
9781483282435

About the Editor

David Aminoff

Ratings and Reviews