Black Seeds (Nigella sativa)

Black Seeds (Nigella sativa)

Pharmacological and Therapeutic Applications

1st Edition - September 23, 2021

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  • Editors: Andleeb Khan, Muneeb Rehman
  • Paperback ISBN: 9780128244623
  • eBook ISBN: 9780323859295

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Black Seeds (Nigella sativa) is a comprehensive resource covering all aspects of this medicinal plant, well-known for its positive effects in many human ailments. It has been used to promote health and fight diseases, and has been found to have antioxidant, antihypertensive, anti-diabetic, anti-inflammatory, and analgesic effects. It has also been known to have antimicrobial, anticancer, neuro-protectant, cardio protectant, immunomodulator, hepatic protectant characteristics. Thymoquinone, the active compound of the plant, also exhibits these protective qualities against many disorders. This book summarizes the effect of this plant on all the organ systems of the body. Black Seeds (Nigella sativa) is a comprehensive resource for researchers working in pharmacology, food chemistry and pharmaceutical chemistry, both in industry and academia.

Key Features

  • Contains global coverage of the latest research on the pharmacological properties of Nigella sativa
    • Includes the medicinal effects of Nigella sativa: antioxidant, antihypertensive, anti-diabetic, anti-inflammatory, antimicrobial, and anticancer effects among many others
    • Features many figures with mechanisms and tables to illustrate key details about Nigella sativa


    Researchers working in organic chemistry, food chemistry and pharmaceutical chemistry, both in industry and academia. Researchers working in chemical engineering, food technology, biochemistry and pharmacology

    Table of Contents

    • 1. History and traditional uses of Black seeds (Nigella sativa)

      2. Nigella sativa: From Chemistry to Medicine

      3. Nigella sativa, a cure for every disease: Phytochemistry, Biological Activities and Clinical Trials

      4. A Review of Nigella sativa and its Active Principles as Anticancer Agents

      5. Dermatological effects of Nigella sativa: A cosmetic and therapeutic approach

      6. Nigella sativa and its chemical constituents: A promising approach against neurodegenerative disorders

      7. A Meta-analysis of Nigella sativa in Respiratory Disorders

      8. Nigella sativa and its active principles: Potential food for healthy living

      9. Therapeutic effects of Nigella sativa on hormonal dysfunctions

      10. The cardio protective effect of thymoquinone from Nigella sativa

      11. Black seeds of Nigella Sativa: a remedy for advanced cancer therapeutics with special reference to nanotechnology

      12. Nigella sativa as a Therapeutic Candidate for Arthritis and Related Disorders

      13. Therapeutic potential of Nigella sativa in the Prevention of Aggregation and Glycation of Proteins

      14. Role of Nigella sativa as immunomodulator

      15. Gastrointestinal abnormalities and Nigella sativa: A Narrative Review of Preclinical and Clinical Studies

      16. Anti-viral effects of black seeds: Effect on COVID-19

      17. Black Seed (Nigella Sativa): Pharmacological and Therapeutic Applications in endocrine dysfunction

      18. Nigella sativa and Prevention of Nephrotoxicity: A Comprehensive update

      19. Nigella sativa: A promise for industrial and agricultural economic growth


    Product details

    • No. of pages: 486
    • Language: English
    • Copyright: © Elsevier 2021
    • Published: September 23, 2021
    • Imprint: Elsevier
    • Paperback ISBN: 9780128244623
    • eBook ISBN: 9780323859295

    About the Editors

    Andleeb Khan

    Andleeb Khan (Ph.D.) is Assistant Professor at Jazan University, Saudi Arabia. She has completed her doctorate from Jamia Hamdard, New Delhi, India in Toxicology with specialization in natural and active constituents from plants for prevention of Alzheimer’s Disease. She has teaching and research experience of more than ten years in neurodegenerative disorders and their prevention with medicinal plants, their active principles and nanoformulations. She has published her research in national and international journals and contributed many book chapters with international publishers including Springer Nature and Elsevier. Currently, Dr. Khan is engaged in studying the molecular mechanism of Azheimer’s disease, Ischemic stroke, Parkinson’s Disease and their prevention by various active principles from natural sources and nanoformulations.

    Affiliations and Expertise

    Assistant Professor, Jazan University, Saudi Arabia

    Muneeb Rehman

    Muneeb U Rehman (Ph.D.) is a Faculty member at College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. He holds a doctorate in Toxicology (specialization in cancer biology and natural product research) from Jamia Hamdard, New Delhi, India Dr. Rehman has more than 10 years of research and teaching experience in the field of toxicology, biochemistry, cancer biology, natural product research and pharmacogenomics. He is the recipient of several national and international fellowships and awards. He has published more than 100 research papers in peer-reviewed, international journals, and has 7 edited books and 39 book chapters to his name. Currently, Dr. Rehman is engaged in studying the molecular mechanisms of cancer prevention by natural products and the role of pharmacogenomics and toxicogenomics in evaluating the effectiveness and safety of drugs

    Affiliations and Expertise

    Faculty Member, Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia

    Ratings and Reviews

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    • Ayasha n. Mon Oct 11 2021

      Great book

      This book gives really great insight into the uses and benefits of Nigella sativa. This is a must read book and I highly recommend to the authors.

    • Gulzar Tue Oct 05 2021

      Gulzar Ahmed Rather

      This book is filled with information on the Nigella sativa. This book will give readers with fresh insights, and I highly suggest it to them..

    • Arif S. Mon Oct 04 2021

      Dr. Arif Siddiqui

      This is excellent and informative book. Plant details is deeply describe about the species' of N. sativa. I really like this book and hope authors happy to read this book.

    • Dr R. Mon Oct 04 2021

      Dr Hina Rashid

      The book provides exhaustive details about the pharmacological aspects of Nigella sativa. It is a must read for the researchers perusing interests in plant based medicine. Presents most intricate details in easy to understand manner.

    • Dr. A. Wed Sep 29 2021

      Dr. Syed Wajahat Ali

      A well-compiled book with excellent knowledge about the topic. There are multiple books on Nigella sativa but this book is a broad compilation of almost all the activities exhibited by the plant at one place. I highly recommend this book to the authors.