A. Meister, Glutathione Metabolism.
H.F. Gilbert, Thiol/Disulfide Exchange Equilibria and Disulfide Bond Stability.
P. Wardman and C. von Sonntag, Kinetic Factors That Control the Fate of Thiyl Radicals in Cells.
C. Schineich, Kinetics of Thiol Reactions.
S.A. Everett and P. Wardman, Perthiols as Antioxidants: Radical-Scavenging and Pro-oxidative Mechanisms.
S.C. Kundu and R.L. Willson, Thiyl (Sulfhydryl/Thiol) Free Radical Reactions, Vitamins, Beta-Carotene, and Superoxide Dismutase in Oxidative Stress: Design and Interpretation of Enzymatic Studies.
C.C. Winterbourn and D. Metodiewa, Reaction of Superoxide with Glutathione and Other Thiols.
L.M. Weiner, Quantitative Determination of Thiol Groups in Low and High Molecular Weight Compounds by Electron Paramagnetic Resonance.
E. Cadenas, Thiyl Radical Formation during Thiol Oxidation by Ferrylmyoglobin.
R. Munday, In Vivo Toxicity of Thiols: Relationship to Rate of One-Electron Oxidation by Oxyhemoglobin.
Chemical Basis of Thiol/Disulfide Measurements:
N.S. Kosower and E.M. Kosower, Diamide: An Oxidant Probe for Thiols.
E.M. Kosower and N.S. Kosower, Bromobimane Probes for Thiols.
G.L. Newton and R.C. Fahey, Determination of Biothiols by Bromobimane Labeling and High-Performance Liquid Chromatography.
R. Singh, G.V. Lamoureux, W.J. Lees, and G.M. Whitesides, Reagents for Rapid Reduction of Disulfide Bonds.
K. Becker and R.H. Schirmer, 1,3-Bis(2-chloroethyl)-1-nitrosourea as Thiol-Carbamoylating Agent in Biological Systems.
Monothiols: Measurement in Organs, Cells, Organel
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@introbul:Key Features @bul:* Prevention of oxidative stress
- Redox regulation of metabolism
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California Institute of Technology, Division of Biology, Pasadena, U.S.A.
The Salk Institute, La Jolla, CA, USA
Helmut Sies is an Honorary Member of the American Society for Biochemistry and Molecular Biology. He received an Honorary Ph.D. from the University of Buenos Aires, Argentina in 1996. Dr. Sies is a member of the Northrhine-Westphalian Academy of Sciences, Germany, and a Corresponding Member of both the Academy of Sciences of Heidelberg, Germany, and the Academy of Medicine, Buenos Aires, Argentina. He has received many awards and prizes, including the FEBS Anniversary Prize awarded by the Federation of European Biochemical Societies, 1978; the Distinguished Foreign Scholar award, MASUA, 1985; the Silver Medal, Karolinska Institute, Stockholm, 1986; the Ernst Jung Preis fur Medizin, 1988; the Claudius-Galenus-Preis, 1990; and the ISFE-Preis, 1994. Dr. Sies sereves on the editorial board and advisory committee for twelve journals, has edited numerous books, and has published more than 400 original articles and chapters. He received his M.D. at the University of Munich in 1967 and currently serves as Full Professor and Chairman of the Department of Physiological Chemistry at the University of Düsseldorf.
Institut Fur Physiologische Chemie, Germany