Biothermodynamics, Part D - 1st Edition - ISBN: 9780123860033, 9780123860040

Biothermodynamics, Part D, Volume 492

1st Edition

Serial Volume Editors: Michael Johnson Jo Holt Gary Ackers
eBook ISBN: 9780123860040
Hardcover ISBN: 9780123860033
Imprint: Academic Press
Published Date: 25th February 2011
Page Count: 369
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Table of Contents

  1. A Thermodynamic Approach for the Targeting of Nucleic Acid Structures Using Their Complementary Single Strands
  2. Hui-Ting Lee, Caroline Carr, Hollie Siebler, Lela Waters, Irine Khutsishvili, Fany Iseka, Brian Domack, Chris M. Olsen, and Luis Marky

  3. Thermodynamics of Biological Processes
  4. Hernan G. Garcia, Jane Kondev, Nigel Orme, Julie Theriot and Rob Phillips

  5. Protein stability in the presence of co-solutes
  6. Luis Marcelo F. Holthauzen, Matthew Auton, Mikhail Sineva and Jorg Rosgen

  7. Small Angle X-ray Scattering Studies of Peptide-Lipid Interactions using the Mouse Paneth Cell α-Defensin Cryptdin-4
  8. Abhijit Mishra, Kenneth P. Tai, Nathan W. Schmidt, André J. Ouellette and Gerard C. L. Wong

  9. Synergy of molecular dynamics and isothermal titration calorimetry in studies of allostery
  10. Rebecca Strawn, Thomas Stockner, Milan Melichercik, Lihua Jin, Wei-Feng Xue, Jannette Carey and Rüdiger Ettrich

  11. Using tryptophan fluorescence to measure the stability of membrane proteins folded in liposomes
  12. C. Preston Moon1 and Karen G. Fleming

  13. Non-B Conformations of CAG Repeats Using 2-aminopurine
  14. Natalya N. Degtyareva and Jeffrey T. Petty

  15. Disulfide bond-mediated passenger domain stalling as a structural probe of autotransporter outer membrane secretion in vivo
  16. Jonathan P. Renn & Patricia L. Clark


  17. Strategies for the Thermodynamic Characterization of Linked Binding/Local Folding Reactions Within the Native State: Application to the LID Domain of Adenylate Kinase from Escherichia coli
  18. Travis P. Schrank, W. Austin Elam, Jing Li and Vincent J. Hilser

  19. Fluorescence detected sedimentation in dilute and highly concentrated solutions

Jonathan S. Kingsbury and Thomas M. Laue


The use of thermodynamics in biological research can be equated to an energy book-keeping system. While the structure and function of a molecule is important, it is equally important to know what drives the energy force. This volume presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions.

Key Features

Elucidates the relationships between structure and energetics and their applications to molecular design, aiding researchers in the design of medically important molecules
Provides a "must-have" methods volume that keeps MIE buyers and online subscribers up-to-date with the latest research
* Offers step-by-step lab instructions, including necessary equipment, from a global research community


Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists


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© Academic Press 2011
Academic Press
eBook ISBN:
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About the Serial Volume Editors

Michael Johnson Serial Volume Editor

Affiliations and Expertise

University of Virginia Health Sciences Center, Charlottesville, USA

Jo Holt Serial Volume Editor

Affiliations and Expertise

Washington University Medical Center, St. Louis, MO, USA

Gary Ackers Serial Volume Editor

Affiliations and Expertise

Washington University School of Medicine, St. Louis, Mo, USA