Preface. Editorial Board. List of contributors. Purification of plasmids for gene therapy and DNA vaccination (D.M.F. Prazeres, G.A. Monteiro, G.N.M. Ferreira, M.M. Diogo, S.C. Ribeiro, J.M.S. Cabral). RNA interference: mechanisms and applications (A. Fjose, S. Ellingsen, A. Wargelius, Hee-Chan Seo). Liposomes as drug carriers: a technological approach (M. Brandl). Reverse micelles and protein biotechnology (E.P. Melo, M.R. Aires-Barros, J.M.S. Cabral). P53-responsive genes and the potential for cancer diagnostics and therapeutics development (Hao Xu, M. R. El-Gewely). Bioinformatics and receptor mechanisms of psychotropic drugs (S.G. Dahl, Ø. Edvardsen, K. Kristiansen, I. Sylte). Enzymatic studies on the key enzymes of vitamin D metabolism; 1&agr;-hydroxylase (CYP27B1) and 24-hydroxylase (CYP24) (K. Inouye, T. Sakaki). Genomics and plant breeding (S. Aljanabi). Transgenics in crops (Yi Li, Y.H. Wu, R. McAvoy, Hui Duan). Agricultural biotechnology in developing countries (A. Dookun). Index of authors. Keyword index.