Scope. Editors and Contributors. Introduction (M.R. El-Gewely). Biotechnology domain (M.R. El-Gewely). Application of two-dimensional protein gels in biotechnology (R.A. VanBogelen, E.R. Olson). Prokaryotic promotors in biotechnology (M.A. Goldstein, R.H. Doi). Comparative methods for identifying functional domains in protein sequences (S. Henikoff). Peptide and protein display on the surface of filamentous bacteriophage (F. Felici et al.). Aptamers as potential nucleic acid pharmaceuticals (A.D. Ellington, R. Conrad). Towards a new concept of gene inactivation: specific RNA cleavage by endogenous ribonuclease P (R.K. Hartmann et al.). Artificial cells with emphasis on bioencapsulation in biotechnology (T.M.S. Chang). The production of recombinant human erythropoietin (N. Inoue et al.). Lipases and esterases: a review of their sequences, structure and evolution (H.W. Anthonsen et al.). Solid-phase technology: magnetic beads to improve nucleic acid detection and analysis (J. Lundeberg, F. Larsen). Ultrasensitive enzyme immunoassay (S. Hashida et al.). The politics of patent legislation in biotechnology: an international view (G.K. Rosendal). Index of authors. Keyword index.