Biotechnology and Safety Assessment

3rd Edition

Editors: John Thomas Roy Fuchs
Hardcover ISBN: 9780126887211
eBook ISBN: 9780080528182
Imprint: Academic Press
Published Date: 29th July 2002
Page Count: 400
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A comprehensive treatise on new developments in biotechnology, the authors of Biotechnology and Safety Assessment, 3e, bring readers an up-to-date review of food safety issues, pre-clinical safety and development of new foods and drugs, plant biotechnology, food allergies and safety assessment, and consumer benefits with regard to genetically modified food.

Tomorrow's foods will be obtained from genetically modified crops, offering consumers higher nutritional value and more of it. Our medications will be obtained through a variety of biotechnological procedures yielding more potent and specific medications for diseases and vaccines. In order to make this view of the future come to light, John A. Thomas and Roy L. Fuchs have updated their classic in order to keep readers one step ahead.

Written by internationally recognized molecular biologists, plant agronomists, microbiologists, toxicologists, nutritionists, and regulatory authorities, this third edition is an excellent and authoritative resource, making it a valuable resource to any biomedical library or scientific bookshelf.

Key Features

Key Features

  • Provides timely coverage on topics of agribiotechnology and biotherapeutics
  • Describes the recent progress in genetically modified crops and their safety
  • Presents an update of the newer developments in therapeutic agents
  • Discusses role of genetically modified microorganisms in the development of new food products
  • Outlines various global regulatory issues relating to GM crops
  • Addresses environmental and ecological topics related to GM crops


Toxicologists, phamacologists, regulatory agency professionals, environmental scientists, and agricultural scientists.

Table of Contents

Contributors Preface Chapter 1. Using Plant Biotechnology to Reduce Allergens in Food: Status and Future Potential Introduction Characteristics of Food Allergens Traditional Plant Breeding Methods for Reducing Allergenicity Use of Genetic Engineering to Reduce Allergenic Potential Concluding Remarks References Chapter 2. Experience with Biosafety Research and Postmarket Environmental Monitoring in Risk Management of Crops Derived from Plant Biotechnology Introduction End Points and Definitions Regulatory Aspects Biosafety Research on Virus-Resistant Sugar Beet Using Biogeographical Data for Biosafety Research Monitoring of Insect-Resistant Maize Concluding Remarks: Linking Biosafety Research and Monitoring References Chapter 3. Safety Assessment of Foods and Food Ingredients Produced by Genetically Modified Microorganisms Introduction Issues in Food and Food Ingredients Produced From rDNA Concepts in Safety Testing Regulatory Requirements Case Studies in Safety Assessment Concluding Remarks References Chapter 4. Food Safety Assessment of Current and Future Plant Biotechnology Products Introduction Safety Evaluation and the Substantial Equivalence Paradigm How are Genetically Modified Foods Evaluated for Food Safety? Future Trends in Food Safety Assessments Concluding Remarks and Future Prospects References Chapter 5. Plant Biotechnology Products with Direct Consumer Benefits Introduction Improved Nutritional Qualities Products with Enhanced Quality Traits Concluding Remarks References Chapter 6. Animal Feeds from Crops Derived through Biotechnology: Farm Animal Performance and Safety Introduction Crops Fed to Farm Animals in the United States Characteristics of Intake and Digestion by Farm Animals Performance, Health, and Nutrient Utilization for


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© Academic Press 2003
Academic Press
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About the Editor

John Thomas

Affiliations and Expertise

University of Texas Health Sciece Center, San Antonio, U.S.A.

Roy Fuchs

Affiliations and Expertise

Mosanto Company, St. Louis, Missouri, U.S.A.


"This book is a valuable update for those wishing to keep abreast of the potential of food biotechnology and also to construct safety evaluation and assurance programs for the derived food products." -TRENDS IN FOOD SCIENCE & TECHNOLOGY (May 2003) "The book is a treasure trove of useful information...Thomas and Fuchs provide a useful, fact-filled handbook of biotechnology biosafety data. ...If you have only one source of biosafety data, this is for you." —NATURE BIOTECHNOLOGY (October 2002) "...should be of interest to toxicologists, pharmacologists, nutritionists, and those responsible for assessing risk/benefits, environmental impact and safety of GM products." —SCITECH BOOK NEWS(December 2002)