Biosynthesis, Modification, and Processing of Cellular and Viral Polyproteins
1st Edition
Description
Biosynthesis, Modification, and Processing of Cellular and Viral Polyproteins presents the proceedings of the international conference held in Hamburg-Blankenese on May 27-31, 1980. The book discusses topics on polyproteins, polyfunctional proteins, precursor proteins, as well as the differences in synthesis and processing of ACTH/endorphin peptides in primary cultures of anterior and intermediate lobes of the pituitary. The text also presents evidence for a self-cleaving precursor of virus-coded protease, RNA-replicase, and VPg; and the role of Pr180gag-pol in the characterization and genetic analysis of retrovirus maturation.
Table of Contents
Contributors
Foreword
Preface
Opening Remarks
Polyproteins-Polyfunctional Proteins-Precursor Proteins
I. Biosynthesis of Precursors
Neuropolypeptides Illustrate a New Perspective in Mammalian Protein Synthesis—The Composite Common Precursor
A. Hypothalamic Precursors
Biosynthetic Precursors of Neurohormones: High Molecular Weight Immunoreactive Forms of Neurophysin:Vasopressin and of Somatostatin
On the Biosynthetic Origin of Neurophysin-Neurohypophyseal Peptide Hormone Complexes
Hypothalamic mRNA-Directed Synthesis of Neuropolypeptides: Immunological Identification of Precursors to Neurophysin II/Arginine Vasopressin and to Neurophysin I/Oxytocin
Efforts Directed Toward an Understanding of the Biosynthesis of the Hypothalamic-Releasing Hormones
Immunological, Enzymological, and Chemical Characterization of a Large Somatostatin-Like Polypeptide
B. Pituitary Precursors
Pro-Opiomelanocortin: A New Concept Issued from ACTH and LPH Biosynthetic Studies
Biosynthesis of the Enkephalins: Precursors and Intermediates
C. Viral Precursors
Synthesis and Maturation of the Vesicular Stomatitis Virus Glycoprotein
II. Processing and Modifications
Differences in Synthesis and Processing of ACTH/Endorphin Peptides in Primary Cultures of Anterior and Intermediate Lobes of the Pituitary
Post-Translational Processing of Pro-ACTH/Endorphin in Rat Pituitary
The Role of the Carbohydrate in the Stabilization, Processing, and Packaging of Pro-ACTH/αMSH-Endorphin in Frog and Mouse Pituitary Neurointermediate Lobes
Polyadenylylation of Reovirus Proteins
Processing of the Influenza Virus Hemagglutinin
Alte
Details
- No. of pages:
- 360
- Language:
- English
- Copyright:
- © Academic Press 1980
- Published:
- 1st January 1980
- Imprint:
- Academic Press
- eBook ISBN:
- 9780323154215