The bioseparation engineering of today includes downstream process engineering such as waste water, material and gas treatment. Taking this tendency into account, bioseparation engineers gathered in Japan as a special research group under the main theme of "Recovery and Recycle of Resources to Protect the Global Environment".

The scope of this book is based on the conference, and deals not only with recent advances in bioseparation engineering in a narrow sence, but also the environmental engineering which includes waste water treatment and bioremediation. The contributors of this book cover many disciplines such as chemical engineering, analytical chemistry, biochemistry, and microbiology.

Bioseparation Engineering will stimulate young engineers and scientists who will develop bioseparation engineering further in the 21st century, and contribute to a world-wide attention to the global environment

Table of Contents

Contents. Preface. Acknowledgements. Chapter 1. Adsorption, Chromatography and Membrane Separations. Recent advances in membrane technology that could improve resource recovery and recycle: Fluid mechanics, surface science and bioaffinity (G. Belfort). Stabilization of target protein during bioseparation (X.-L. Feng, Y.-T. Jin, Z. -G. Su). Bioseparation of natural products (C. Keim, M.R. Ladisch). On-line recovery of large molecules from mixture solution using semi-continuous size exclusion chromatography (Y.-M. Kim, W. -J. Chang, Y. -M. Koo). Dye adsorption by activated carbon in centrifugal field (C.-C. Lin, H.-S. Liu). Formation and structural change of cake during crossflow microfiltration of microbial cell suspension containing fine particles (T. Tanaka, N. Yamagiwa, T. Nagano, M. Taniguchi, K. Nakanishi). Continuous separation of ternary mixture of amino acids using rotating annular chromatography with partial recycle of effluent (T. Fukumura, V.M. Bhandari, A. Kitakawa, T. Yonemoto). Mass transfer characteristics of a perfusion-type gel analyzed by shallow bed method (M. Terashima., S. Nishimura, H. Yoshida). Fouling of cheese whey during reverse osmosis and precipitation of calcium phosphate (H. Tsuge, Y. Tanaka, N. Hisamatsu). Separation of dead cells from culture broth by using dielectrophoresis (M. Hakoda, N. Shiragami). Microcalorimetric studies of interactions between proteins and hydrophobic ligands in hydrophobic interaction chromatography: Effects of ligand chain length, density, and the amount of bound protein (F. -Y. Lin, W.-Y. Chen, R.-C. Ruaan, H. -M. Huang). Membrane phase separation of aqueous/alcohol biphase mixture and its application for enzyme bioreactor (Y. Isono, M. Nakajima). Microfabricated structures for bioseparation (J.W. Hong, K. Hosokawa, T. Fujii, M. Seki, I. Endo). Production of a human IgM-type antibody and preparation of combinatorial library by recombinant Saccharomyces cerevisiae (N.


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© 2000
Elsevier Science
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About the editors

I. Endo

Affiliations and Expertise

Biochemical Systems Laboratory, RIKEN Institute, Saitama, Japan

T. Nagamune

Affiliations and Expertise

Department of Chemistry and Biotechnology, University of Tokyo, Tokyo, Japan

S. Katoh

Affiliations and Expertise

Department of Chemical Science and Engineering, Kobe University, Kobe, Japan

T. Yonemoto

Affiliations and Expertise

Department of Chemical Engineering, University of Tohoku, Sendai, Japan