Biosensors for Medical Applications

Biosensors for Medical Applications

1st Edition - August 21, 2012

Write a review

  • Editor: Séamus Higson
  • eBook ISBN: 9780857097187

Purchase options

Purchase options
DRM-free (EPub, PDF, Mobi)
Sales tax will be calculated at check-out

Institutional Subscription

Free Global Shipping
No minimum order

Description

Biomedical sensors are an essential tool in the detection and monitoring of a wide range of medical conditions from cancer to Parkinson’s disease. Biosensors for medical applications provides a comprehensive review of established, cutting edge and future trends in biomedical sensors and their applications.Part one focuses on key principles and transduction approaches, reviewing electrochemical, piezoelectric and nano-sized biosensors. Impedence interrogated affinity biosensors for medical applications and practical applications of enzyme biosensors are explored, before part two goes on to review specific medical applications. Biosensors for DNA and RNA detection and characterization, disease biomarker detection, and the use of affibodies as an alternative to antibodies in cancer marker biosensors are investigated, along with biosensors for drug testing and discovery, non-invasive measurements, and wearable biosensors for medical applications.With its distinguished editor and international team of expert contributors, Biosensors for medical applications is an essential guide for all those involved in the research, design, production and use of medical biosensors.

Key Features

  • Provides a comprehensive review of established, cutting edge and future trends in biomedical sensors and their applications
  • Examines key principles and transduction approaches, reviewing electrochemical, piezoelectric and nano-sized biosensors
  • Reviews biosensors for DNA and RNA detection and characterisation, disease biomarker detection, and the use of affibodies as an alternative to antibodies in cancer marker biosensors

Readership

R&D professionals within the healthcare industry; Academics in the medical, biomedical and material science fields; Clinicians

Table of Contents

  • Contributor contact details

    Woodhead Publishing Series in Biomaterials

    Introduction to biosensors

    Part I: Principles and transduction approaches

    Chapter 1: Electrochemical biosensors for medical applications

    Abstract:

    1.1 Introduction to electrochemical sensors

    1.2 Electrochemical biosensing applications

    1.3 Label-free approaches to electrochemical sensors

    1.4 Conclusion and future trends

    Chapter 2: Piezoelectric biosensors for medical applications

    Abstract:

    2.1 Introduction

    2.2 Piezoelectric immunosensors

    2.3 Piezoelectric genosensors

    2.4 Piezoelectric biosensors with bio-mimetic receptors

    2.5 Conclusions and future trends

    Chapter 3: Nano-sized biosensors for medical applications

    Abstract:

    3.1 Introduction

    3.2 Sensing modalities

    3.3 Nanomaterial properties

    3.4 Biosensors on the nanoscale

    3.5 Conclusions

    Chapter 4: Impedance interrogated affinity biosensors for medical applications: novel targets and mechanistic studies

    Abstract:

    4.1 Small molecule binding

    4.2 Supramolecular structures

    4.3 Electrochemical biosensor for clinical diagnostics

    4.4 Challenges of carbohydrate sensing

    4.5 Bioreceptors for carbohydrate sensing

    4.6 Enzymes that act on carbohydrates

    4.7 Impedimetric glucose biosensors

    4.8 Impedimetric bacterial and viral immunosensors

    4.9 Impedance and pathogens

    4.10 Bioreceptors used in impedimetric pathogenic biosensor construction

    4.11 Detection of exposure to infection

    4.12 Conclusion

    Chapter 5: Practical applications and protocols for enzyme biosensors

    Abstract:

    5.1 Introduction

    5.2 Methods and approaches for using biosensors

    5.3 Protocols for enzyme biosensors

    Method

    5.4 Problems arising from the construction and use of biosensors

    Part II: Applications of medical biosensors

    Chapter 6: Biosensors for DNA and RNA detection and characterization

    Abstract:

    6.1 Introduction to nucleic acids and base pairing

    6.2 Principles of DNA/RNA sensing

    6.3 Electrochemical DNA sensing

    6.4 Optical DNA sensing

    6.5 Quartz crystal microbalance and surface acoustic wave sensors

    6.6 Microcantilever oligonucleotide sensors

    6.7 Conclusions

    Chapter 7: Biosensors for disease biomarker detection

    Abstract:

    7.1 Introduction

    7.2 Disease biomarkers

    7.3 Established technologies for disease biomarker detection

    7.4 Proteins at surfaces

    7.5 Emerging technologies for disease biomarker detection

    7.6 Future trends

    7.7 Sources of further information and advice

    Chapter 8: Affibodies as an alternative to antibodies in biosensors for cancer markers

    Abstract:

    8.1 Introduction: cancer

    8.2 Breast cancer

    8.3 Human epidermal growth factor receptor 2 (HER2)

    8.4 The immunoassay

    8.5 Biosensors

    8.6 Problems with antibodies

    8.7 Affibodies

    Chapter 9: Biosensors for drug testing and discovery

    Abstract:

    9.1 Introduction

    9.2 Types of biosensor

    9.3 Conclusion

    9.4 Acknowledgements

    Chapter 10: Biosensors for non-invasive measurements

    Abstract:

    10.1 Introduction

    10.2 Biosensors for the detection of alcohol and lactate

    10.3 Detection using electrochemical and amperometric biosensors

    10.4 Detection using optical biosensors

    10.5 Conclusions

    Chapter 11: Wearable biosensors for medical applications

    Abstract:

    11.1 Introduction

    11.2 Background

    11.3 Considerations and requirements for wearable sensors

    11.4 Types of wearable sensors

    11.5 Temperature sensors

    11.6 Mechanical sensors

    11.7 Electrical sensors

    11.8 Biological and chemical sensing

    11.9 Clinical applications

    11.10 Future trends

    11.11 Sources of further information and advice

    Index

Product details

  • No. of pages: 360
  • Language: English
  • Copyright: © Woodhead Publishing 2012
  • Published: August 21, 2012
  • Imprint: Woodhead Publishing
  • eBook ISBN: 9780857097187

About the Editor

Séamus Higson

Seamus Higson is Professor of Bio- and Electro-analysis and Commercial Director of Cranfield Health at Cranfield University, UK. A member of the UK Engineering and Physical Sciences Research Council (EPSRC), Professor Higson serves in an advisory and/or consultative capacity for a number of public bodies, and has written extensively on a wide range of topics within the fields of medicine, biotechnology, materials science and health.

Affiliations and Expertise

Cranfield University, UK

Ratings and Reviews

Write a review

There are currently no reviews for "Biosensors for Medical Applications"