Bioprocess Engineering

Bioprocess Engineering: Kinetics, Sustainability, and Reactor Design, Second Edition, provides a comprehensive resource on bioprocess kinetics, bioprocess systems, sustainability, and reaction engineering. Author Dr. Shijie Liu reviews the relevant fundamentals of chemical kinetics, batch and continuous reactors, biochemistry, microbiology, molecular biology, reaction engineering, and bioprocess systems engineering, also introducing key principles that enable bioprocess engineers to engage in analysis, optimization, and design with consistent control over biological and chemical transformations.

The quantitative treatment of bioprocesses is the central theme in this book, with more advanced techniques and applications being covered in depth. This updated edition reflects advances that are transforming the field, ranging from genetic sequencing, to new techniques for producing proteins from recombinant DNA, and from green chemistry, to process stability and sustainability.

The book introduces techniques with broad applications, including the conversion of renewable biomass, the production of chemicals, materials, pharmaceuticals, biologics, and commodities, medical applications, such as tissue engineering and gene therapy, and solving critical environmental problems.

• Includes the mechanistic description of biotransformations and chemical transformations
• Provides quantitative descriptions of bioprocesses
• Contains extensive illustrative drawings, which make the understanding of the subject easy
• Includes bioprocess kinetics and reactor analysis
• Contains examples of the various process parameters, their significance, and their specific practical use
• Incorporates sustainability concepts into the various bioprocesses

Senior undergraduate students and graduate students in Chemical and Bioprocess Engineering and Biological Engineering Research Engineers and Scientists in Biotechnology and Bioprocess Design

Chapter 1. Introduction

Chapter 2. An Overview of Biological Basics

Chapter 3. An Overview of Chemical Reaction Analysis

Chapter 4. Batch Reactor

Chapter 5. Ideal Flow Reactors

Chapter 6. Kinetic Theory and Reaction Kinetics

Chapter 7 Parametric Estimation

Chapter 8. Enzymes

NEW! Chapter 9. Allosteric Enzymes and Regulations

9.1. Reactions in Life

9.2. Allostericity and cooperativity

9.2.1 Single binding site and saturation binding

9.2.2 Multiple binding sites and Morpheein mechanism

9.3. Enzyme binding and transport

9.4. Kinetics of allosteric enzyme

9.5. Allosteric regulations

9.6. Summary

Recommended Reading Materials

Problems

NEW! Chapter 10. Adsorption

10.1 Introduction

10.2 Thermodynamics of adsorption

10.3 Ideal surface and Langmuir adsorption

10.3.1 Collision theory and adsorption rate

10.3.2 Langmuir adsorption isotherm

10.4 Idealization of non-ideal adsorption and multilayer adsorption

10.4.1 Idealization of non-uniform surface and surface interaction

10.4.2 Multilayer adsorption kinetics

10.4.3 Adsorption isotherm

10.4.4 BET isotherm

10.5 Pore Size and Surface Characterization

10.6. Applications of adsorption

10.7 Summary

Recommended Reading Materials

Problems

Chapter 11. Catalysis and Chemical Reactions on Solid Surfaces

Chapter 12. Cell Growth and Metabolism

Chapter 13. Kinetics of Cell Growth and Batch Cultivation

Chapter 14. Cell Growth and Fermentation

Chapter 15 Ideal Fed-Batch Reactor

Chapter 16. Evolution and Genetic Engineering

Chapter 17. Sustainability: Perspective</P