Bioprocess Engineering

1st Edition

Kinetics, Sustainability, and Reactor Design

eBook ISBN: 9780444595225
Imprint: Elsevier
Published Date: 28th September 2012
Page Count: 1000
147.95 + applicable tax
94.00 + applicable tax
106.00 + applicable tax
15000.00 + applicable tax
Compatible Not compatible
VitalSource PC, Mac, iPhone & iPad Amazon Kindle eReader
ePub & PDF Apple & PC desktop. Mobile devices (Apple & Android) Amazon Kindle eReader
Mobi Amazon Kindle eReader Anything else

Institutional Access


Bioprocess Engineering involves the design and development of equipment and processes for the manufacturing of products such as food, feed, pharmaceuticals, nutraceuticals, chemicals, and polymers and paper from biological materials. It also deals with studying various biotechnological processes. "Bioprocess Kinetics and Systems Engineering" first of its kind contains systematic and comprehensive content on bioprocess kinetics, bioprocess systems, sustainability and reaction engineering. Dr. Shijie Liu reviews the relevant fundamentals of chemical kinetics-including batch and continuous reactors, biochemistry, microbiology, molecular biology, reaction engineering, and bioprocess systems engineering- introducing key principles that enable bioprocess engineers to engage in the analysis, optimization, design and consistent control over biological and chemical transformations. The quantitative treatment of bioprocesses is the central theme of this book, while more advanced techniques and applications are covered with some depth. Many theoretical derivations and simplifications are used to demonstrate how empirical kinetic models are applicable to complicated bioprocess systems.

Table of Contents



Greek Symbols



Chapter 1. Introduction

1.1 Biological Cycle

1.2 Green Chemistry

1.3 Sustainability

1.4 Biorefinery

1.5 Biotechnology and Bioprocess Engineering

1.6 Mathematics, Biology, and Engineering

1.7 The Story of Penicillin: The Dawn of Bioprocess Engineering

1.8 Bioprocesses: Regulatory Constraints

1.9 The Pillars of Bioprocess Kinetics and Systems Engineering

1.10 Summary

Further Reading


Chapter 2. An Overview of Biological Basics

2.1 Cells and Organisms

2.2 Stem Cell

2.3 Cell Chemistry

2.4 Cell Feed

2.5 Summary

Further Reading


Chapter 3. An Overview of Chemical Reaction Analysis

3.1 Chemical Species

3.2 Chemical Reactions

3.3 Reaction Rates

3.4 Approximate Reactions

3.5 Rate Coefficients

3.6 Stoichiometry

3.7 Yield and Yield Factor

3.8 Reaction Rates Near Equilibrium

3.9 Energy Regularity

3.10 Classification of Multiple Reactions and Selectivity

3.11 Coupled Reactions

3.12 Reactor Mass Balances

3.13 Reaction Energy Balances

3.14 Reactor Momentum Balance

3.15 Ideal Reactors

3.16 Bioprocess Systems Optimization

3.17 Summary

Further Reading


Chapter 4. Batch Reactor

4.1 Isothermal Batch Reactors

4.2 Batch Reactor Sizing

4.3 Non-Isothermal Batch Reactors

4.4 Numerical Solutions of Batch Reactor Problems

4.5 Summary

Further Reading


Chapter 5. Ideal Flow Reactors

5.1 Flow Rate, Residence Time, Space Time, Space Velocity, Dilution Rate

5.2 Plug Flow Reactor

5.3 Gasification and Fischer–Tropsch Technology


No. of pages:
© Elsevier 2013
eBook ISBN:
Hardcover ISBN:
Paperback ISBN:


"Combining biology and chemical engineering, Liu presents this overview of bioprocess engineering, applying typical techniques of the chemical industry to biosynthetic processes…Although formulated as a textbook, the level of detail would also make this suitable as a laboratory reference."--Reference & Research Book News, October 2013