Bioprinting

From Multidisciplinary Design to Emerging Opportunities

1st Edition - May 5, 2022
Editors: Michele Conti, Michele Marino
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 8 5 4 3 0 - 6
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 5 4 3 1 - 3

Bioprinting: From Multidisciplinary Design to Emerging Opportunities describes state-of-the-art techniques and highlights open issues of different aspects that affect the efficienc… Read more

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Bioprinting: From Multidisciplinary Design to Emerging Opportunities describes state-of-the-art techniques and highlights open issues of different aspects that affect the efficiency of bioprinting protocols. Starting from a description of the main bioprinting technologies, the book addresses the most advanced approaches for the design of "on-demand" biomaterials suitable for incorporating biological components, along with the challenges associated with the development of a cellular model, and with the biological read-out. Coverage includes intelligent process design techniques, emerging technologies, and specific applications.

Written by a highly interdisciplinary team of authors and presenting a unified approach to bioprinting, this book is ideal for doctoral and postdoctoral researchers in biotechnology, engineering, and physics, as well as industrial researchers interested in the applications of bioprinting.

Cover image
Title page
Table of Contents
Copyright
Contributors
Preface
Chapter 1. 3D printing technologies and materials in the medical field
1. A brief history of 3D printing
2. Technologies classification
3. 3D printing process
4. 3D printing in the medical field
5. 3D printing materials for surgical simulation
6. Conclusions
Chapter 2. Bioprinting technologies: an overview
1. Introduction
2. Bioink choice for bioprinting applications
3. Extrusion-based bioprinting
4. Droplet-based bioprinting
5. Light-assisted bioprinting
6. Recent trends and future perspectives
7. Conclusions
Chapter 3. Biomaterials for bioprinting
1. Introduction
2. Bioink designs and evaluations
3. Natural polymer-based bioinks
4. Synthetic polymer-based bioinks
5. Ink additives
6. Conclusions and perspectives
Chapter 4. Chemical strategies for 3D printable biomaterials
1. Introduction
2. 3D printable biopolymers: natural or synthetic materials?
3. Tailoring the structure: crosslinking strategies
4. Tailoring the hydrogel function: stimuli-responsive and smart biopolymers
5. Open challenges and future perspectives
Chapter 5. Read-out in bioprinting
1. Introduction
2. Biomaterial ink and bioink characterization
3. Printed structure characterization
4. Biological readouts
5. Conclusions and open problems
Chapter 6. Models and simulations as enabling technologies for bioprinting process design
1. Introduction
2. Theoretical models and computational approaches for bioprinting process design
3. Modeling and simulations for bioink development and print planning
4. Modeling and simulations for postprocessing of bioprinted constructs
5. Open challenges and future directions
6. Conclusions
Chapter 7. Emerging strategies in 3D printed tissue models for in vitro biomedical research
1. Introduction
2. Decellularized extracellular matrix bioinks
3. Bioprinting of human cells with high densities using scaffold-free techniques
4. Embedded 3D printing
5. 3D printed compartmentalized and instrumented tissue models
6. How close are we to 3D printing the future of in vitro biomedicine?
Chapter 8. Bioprinting functional tissues: cell types and a focus on cancer modeling
1. Introduction
2. Cell sources for bioprinting of functional tissues
3. Bioprinting for cancer modeling
4. Application of 3D-bioprinted cancer models
5. 3D-bioprinted cancer models
6. Conclusions and perspectives
Chapter 9. Bioprinting for skeletal tissue regeneration: from current trends to future promises
1. Introduction
2. Grafting-based bone and cartilage tissue engineering
3. 3D-bioprinting in bone and cartilage tissue engineering
4. Clinical challenges: in vitro organ modeling
5. Conclusions
Author contributions
Index

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Michele Conti

Michele Marino