Biomedical Information Technology

Biomedical Information Technology

1st Edition - August 17, 2007

Write a review

  • Editor: David Feng
  • Hardcover ISBN: 9780123735836
  • eBook ISBN: 9780080550725

Purchase options

Purchase options
DRM-free (PDF)
Sales tax will be calculated at check-out

Institutional Subscription

Free Global Shipping
No minimum order


The enormous growth in the field of biotechnology necessitates the utilization of information technology for the management, flow and organization of data. The field continues to evolve with the development of new applications to fit the needs of the biomedicine. From molecular imaging to healthcare knowledge management, the storage, access and analysis of data contributes significantly to biomedical research and practice. All biomedical professionals can benefit from a greater understanding of how data can be efficiently managed and utilized through data compression, modelling, processing, registration, visualization, communication, and large-scale biological computing. In addition Biomedical Information Technology contains practical integrated clinical applications for disease detection, diagnosis, surgery, therapy, and biomedical knowledge discovery, including the latest advances in the field, such as ubiquitous M-Health systems and molecular imaging applications.

Key Features

  • The world's most recognized authorities give their "best practices" ready for implementation
  • Provides professionals with the most up to date and mission critical tools to evaluate the latest advances in the field and current integrated clinical applications
  • Gives new staff the technological fundamentals and updates experienced professionals with the latest practical integrated clinical applications


biomedical and clinical engineers; physicians and surgeons; health physicists; bioinformaticists; biomedical researchers, students, educators; members of the basic science community; IT specialists, healthcare professionals and researchers.

Table of Contents

  • Section I: Technological Fundamentals

    Chapter 1 Medical Imaging
    Dr. Xiaofeng Zhang, Dr. Nadine Smith and Prof. Andrew Webb

    1.1 Introduction
    1.2 Digital radiography
    1.3 Computed tomography
    1.4 Nuclear medicine
    1.5 Ultrasonic imaging
    1.6 Magnetic resonance imaging
    1.7 Diffuse optical imaging
    1.8 Biosignals
    1.9 Appendix
    1.10 Exercises
    1.11 Bibliography
    1.12 Index

    Chapter 2 Electronic Medical Record (EMR)

    Dr. Eugene,Y. S. Lim, Prof. Michael Fulham and Prof. David Dagan Feng

    2.1 Introduction
    2.2 Medical data and patient record
    2.3 Terminology standards – vocabulary and a clinical coding system1
    2.4 Information exchange standards
    2.5 Usability issues in EMR
    2.6 User interface
    2.7 Evaluation
    2.8 EMR system – a case study: a web-based imaging electronic patient history
    2.9 Summary
    2.10 Exercise
    2.11 Bibliography and references
    2.12 Index

    Chapter 3 Image Data Compression and Storage

    Prof. Hong Ren Wu, Dr. Damian M. Tan, Dr. Tom Weidong Cai and Prof. David Dagan Feng

    3.1 Introduction
    3.2 Picture compression
    3.3 Compression in the dicom standard
    3.4 Data compression for dynamic functional images
    3.5 Summary
    3.6 Exercises
    3.7 References
    3.8 Index

    Chapter 4 Content-Based Medical Image Retrieval

    Dr. Tom Weidong Cai, Dr. Jinman Kim and Prof. David Dagan Feng

    4.1 Introduction
    4.2 CBMIR by physical visual features
    4.3 CBMIR by geometric spatial features
    4.4 CBMIR by combination of semantic and visual features
    4.5 CBMIR by physiological functional features
    4.6 Summary
    4.7 Exercises
    4.8 Bibliography and references
    4.9 Index

    Chapter 5 Data Modeling and Simulation

    Dr. Alessandra Bertoldo, Prof. Claudio Cobelli

    5.1 Introduction
    5.2 Compartmental models
    5.3 Model identification
    5.4 Model validation
    5.5 Simulation
    5.6 Case study
    5.7 Quantification of medical images
    5.8 Exercises
    5.9 Bibliography and references

    Chapter 6 Techniques for Parametric Imaging

    Prof. David Dagan Feng, Dr. Lingfeng Wen and Dr. Stefan Eberl

    6.1 Introduction
    6.2 Parametric image estimation methods
    6.3 Noninvasive methods
    6.4 Clinical applications of parametric images
    6.5 Summary
    6.6 Exercise
    6.7 Bibliography and references
    6.8 Index

    Chapter 7 Data Processing and Analysis

    Prof. Chris Wyatt, Prof. Yu-Ping Wang, Prof. Matthew T. Freedman, Prof. Murray Loew and Prof. Yue Wang

    7.1 Introduction
    7.2 Medical image enhancement
    7.3 Medical image segmentation
    7.4 Medical image feature extraction
    7.5 Medical image interpretation
    7.6 Summary
    7.7 Exercises
    7.8 Bibliography
    7.9 Index

    Chapter 8 Data Registration and Fusion

    Dr. Xiu Ying Wang, Dr. Stefan Eberl, Prof. Michael Fulham, Dr. Seu Som and Prof. David Dagan Feng

    8.1 Introduction
    8.2 Fundamentals of biomedical image registration and fusion
    8.3 Feature-based medical image registration
    8.4 Intensity-based registration
    8.5 Hybrid registration and hierarchical registration
    8.6 Hardware registration
    8.7 Assessment of registration accuracy
    8.8 Applications of biomedical image registration and fusion
    8.9 Summary
    8.10 Exercises
    8.11 Bibliography and references
    8.12 Index

    Chapter 9 Data Visualization and Display
    Dr. Jinman Kim, Dr. Tom Weidong Cai, Prof. Michael Fulham, Dr. Stefan Eberl and Prof. David Dagan Feng

    9.1 Introduction
    9.2 Two-Dimensional (2D) visualization techniques
    9.3 Three-Dimensional (3D) visualization techniques
    9.4 Volume navigation interface
    9.5 Volume enhancement and manipulation
    9.6 Large data visualization and optimization
    9.7 Dual-modality PET/CT visualization
    9.8 Data display devices
    9.9 Applications of biomedical visualization
    9.10 Summary
    9.11 Exercises
    9.12 Bibliography and references
    9.13 Index

    Chapter 10 Data Communication and Network Infrastructue

    Prof. Doan B. Hoang and Dr. Andrew J. Simmonds

    10.1 Introduction
    10.2 Transmission and communication technologies
    10.3 The internet and World Wide Web
    10.4 Wireless and mobile technologies in m-health
    10.5 Sensor networks for health monitoring
    10.6 Applications of wireless technologies in telemedicine
    10.7 Summary
    10.8 Exercises
    10.9 Bibliography and references
    10.10 Index

    Chapter 11 Data Security and Protection for Medical Images

    Dr. Eugene, Y. S. Lim

    11.1 Introduction
    11.2 Overview of cryptographic system
    11.3 Digital watermarking
    11.4 Medical image watermarking
    11.5 Region-based reversible watermarking for secure pet image management
    11.6 Summary
    11.7 Exercise
    11.8 Bibliography
    11.8 Index

    Chapter 12 Biological Computing

    Prof. Eric P Hoffman, Erica Reeves, Dr. Yetrib Hathout, Dr. Zuyi Wang and
    Josephine Chen

    12.1 Introduction
    12.2 Overview of genomic methods
    12.3 Overview of proteomic methods
    12.4 Bioinformatics and information infrastructure
    12.5 Data mining and large-scale biological databases
    12.6 Biological event-driven, time-driven and hybrid simulation techniques
    12.7 Summary
    12.8 Bibliography

    Section II: Integrated Applications

    Chapter 13 PACS and Medical Imaging Informatics (MII) for Filmless Hospitals

    Prof. Brent J. Liu and Prof. H.K. Huang

    13.1 Introduction
    13.2 PACS infrastructure
    13.3 PACS components and workflow
    13.4 PACS controller and image archive
    13.5 Large-scale PACS implementation
    13.6 PACS clinical experiences
    13.7 Summary
    13.8 Exercises
    13.9 Bibliography and references
    13.9 Index

    Chapter 14 KMeX: A Knowledge-Based Digital Library for Retrieving Scenario-Specific Medical Text Documents
    Prof. Wesley W. Chu, Dr. Zhenyu Liu, Dr. Wenlei Mao and Dr. Qinghua Zou

    14.1 Introduction
    14.2 Extracting key concepts from documents
    14.3 Transforming similar queries into query templates
    14.4 Topic-oriented directory
    14.5 Phrase-based vector space model for automatic document retrieval
    14.6 Knowledge-based scenario-specific query expansion
    14.7 A system architecture for retrieving scenario-specific free text documents
    14.8 Summary
    14.9 Exercises
    14.10 Bibliography

    Chapter 15 Integrated Multimedia Patient Record Systems
    Dr. Ruth E. Dayhoff, Mr. Peter M. Kuzmak and Mr. Kevin Meldrum

    15.1 Introduction
    15.2 Multimedia patient record
    15.3 Multimedia patient record system architecture components
    15.4 Electronic medical chart components
    15.5 Objects comprising the multimedia patient record
    15.6 Capturing multimedia data at the source
    15.7 DICOM image acquisition
    15.8 Remote data and image viewing across the healthcare network
    15.9 Impact on patient care
    15.10 Summary
    15.11 References

    Chapter 16 Computer-Aided Diagnosis (CAD)
    Prof. Maryellen L. Giger and Dr. Kenji Suzuki

    16.1 Introduction
    16.2 CAD
    16.3 CAD for cancer screening
    16.4 CAD for differential diagnosis
    16.5 Intelligent CAD workstations – indices of similarity and human/computer interfaces
    16.6 Summary
    16.7 Exercises
    16.8 Bibliography
    16.9 Index

    Chapter 17 Clinical Decision Support Systems (CDSS)

    Dr. Peter Weller, Dr. Abdul Roudsari and Prof. Ewart Carson

    17.1 Introduction
    17.2 Overview of CDSS
    17.3 Human diagnostic reasoning
    17.4 A structure for characterising CDSS
    17.5 Decision support tools
    17.6 Decision support systems in the hospital and other healthcare settings
    17.7 Healthcare education applications
    17.8 Verification, validation and evaluation
    17.9 Summary
    17.10 Exercises
    17.11 References
    17.12 Index

    Chapter 18 Medical Robotics and Computer-Integrated Interventional Medicine

    Prof. Russell H. Taylor and Dr. Peter Kazanzides

    18.1 Introduction
    18.2 Technology & Techniques
    18.3 Surgical CAD/CAM
    18.4 Surgical Assistance
    18.5 Summary and conclusion
    18.6 Exercises
    18.7 References
    18.8 Index

    Chapter 19 Functional Techniques for Brain Magnetic Resonance Imaging
    Dr. Sirong Chen, Dr. Kai-Ming Au Yeung and Dr. Gladys Goh Lo

    19.1 Introduction
    19.2 Diffusion-weighted MR imaging in brain
    19.3 MR perfusion imaging in brain
    19.4 Functional MRI (fMRI) using bold techniques
    19.5 Clinical MR spectroscopy in brain
    19.6 Summary
    19.7 Exercises
    19.8 Bibliography and references
    19.9 Index

    Chapter 20 Molecular Imaging in Cancer
    Prof. Kristine Glunde, Dr. Catherine A. Foss and Prof. Zaver M. Bhujwalla

    20.1 Introduction
    20.2 Imaging of gene expression
    20.3 Receptor imaging
    20.4 Enzyme-activated probes
    20.5 Metabolic imaging
    20.6 Imaging of permeability, perfusion, and blood flow
    20.7 Imaging of the tumor microenvironment
    20.8 Multimodality imaging
    20.9 Conclusion
    20.10 Exercises
    20.11 References
    20.12 Index

    Chapter 21 Molecular Imaging in Biology and Pharmacology
    Prof. Sung-Cheng Huang, Prof. Anna M. Wu and Prof. Jorge R. Barrio

    21.1 Introduction and background
    21.2 Considerations for quantitative molecular imaging
    21.3 Design/development of molecular imaging probes
    21.4 Molecular imaging of beta-amyloid and NFT
    21.5 Molecular imaging using antibody probes
    21.6 Some other molecular imaging applications
    21.7 Summary and future perspectives
    21.8 Exercises
    21.9 References
    21.10 Index

    Chapter 22 From Telemedicine to Ubiquitous M-Health: the Evolution of E Health Systems

    Dr. Dejan Raškoviæ, Dr. Aleksandar Milenkoviæ, Prof. Piet C. De Groen and
    Dr. Emil Jovanov

    22.1 Introduction
    22.2 Overview of m-health systems
    22.3 M-health based on Wireless Body Area Networks (WBAN)
    22.4 Wireless intelligent sensors for m-health
    22.5 Wireless mobile devices for m-health
    22.6 Next-generation m-health systems
    22.7 Summary
    22.8 Exercises
    22.9 References
    22.10 Index

    Chapter 23 Multimedia for Future Health – Smart Medical Home………………1

    Dr. Jinman Kim, Dr. Zhiyong Wang, Dr. Tom Weidong Cai and Prof. David Dagan Feng

    23.1 Introduction
    23.2 Multimedia for human-computer interaction
    23.3 Multimedia content management
    23.4 Multimedia delivery
    23.5 Smart medical home
    23.6 Telemedicine in the smart medical home
    23.7 Sensory devices and health monitoring
    23.8 Speech recognition and conversational systems
    23.9 Multimedia technologies for patient education and care
    23.10 Multimedia operating theater and Virtual Reality (VR)
    23.11 Summary
    23.12 Exercises
    23.13 References
    23.15 Index

Product details

  • No. of pages: 552
  • Language: English
  • Copyright: © Academic Press 2007
  • Published: August 17, 2007
  • Imprint: Academic Press
  • Hardcover ISBN: 9780123735836
  • eBook ISBN: 9780080550725

About the Editor

David Feng

Professor David Dagan Feng is Founder and Director, Biomedical and Multimedia Information Technology (BMIT) Research Group, Funding Director, Institute of Biomedical Engineering & Technology (BMET), and Funding Head, School of Information Technology (recently renamed as School of Computer Science), the University of Sydney (USYD), as well as Academic Director, USYD-SJTU (Shanghai Jiao Tong University) Joint Research Alliance. He has been, Head of Department of Computer Science and Associate Dean, Faculty of Science, the University of Sydney; Honorary Research Consultant, Royal Prince Alfred Hospital, the largest hospital in Australia; Chair Professor of Information Technology, Hong Kong Polytechnic University; Scientific Advisor, the 3D Anatomical Human European Institute / Project involving 7 countries; Advisory Professor, Chief Scientist and Chair of the International Advisory Committee, Med-X Research Institute, Shanghai Jiao Tong University; Guest Professor for a number of universities, including Tsinghua University. He received his M.E. in Electrical Engineering & Computer Science (EECS) from Shanghai Jiao Tong University in 1982, M.Sc. in Biocybernetics and Ph.D. in Computer Science from the University of California, Los Angeles (UCLA) in 1985 and 1988, respectively, where he received the Crump Prize for Excellence in Medical Engineering. In conjunction with his team members and students, he has been responsible for more than 50 key research projects, published over 900 scholarly research papers, pioneered several new research directions, and made a number of landmark contributions in his field. He has served as Chair of the International Federation of Automatic Control (IFAC) Technical Committee on Biological and Medical Systems, Special Area Editor / Associate Editor / Editorial Board Member for a dozen of core journals in his area, and Scientific Advisor for a number of prestigious organizations. He has been invited to give over 100 keynote presentations in 23 countries and regions, and has organized / chaired over 100 major international conferences / symposia / workshops. Professor Feng is Fellow of ACS, HKIE, IET, IEEE, and Australian Academy of Technological Sciences and Engineering.

Affiliations and Expertise

Director, Biomedical & Multimedia Information Technology, School of Computer Science, University of Sydney, Sydney, Australia.

Ratings and Reviews

Write a review

There are currently no reviews for "Biomedical Information Technology"