Description

Hydrogels are very important for biomedical applications because they can be chemically manipulated to alter and control the hydrogel’s interaction with cells and tissues. Their flexibility and high water content is similar to that of natural tissue, making them extremely suitable for biomaterials applications. Biomedical hydrogels explores the diverse range and use of hydrogels, focusing on processing methods and novel applications in the field of implants and prostheses.

Part one of this book concentrates on the processing of hydrogels, covering hydrogel swelling behaviour, superabsorbent cellulose-based hydrogels and regulation of novel hydrogel products, as well as chapters focusing on the structure and properties of hydrogels and different fabrication technologies. Part two covers existing and novel applications of hydrogels, including chapters on spinal disc and cartilage replacement implants, hydrogels for ophthalmic prostheses and hydrogels for wound healing applications. The role of hydrogels in imaging implants in situ is also discussed.

With its distinguished editor and international team of contributors, Biomedical hydrogels is an excellent reference for biomedical research scientists and engineers in industry and academia, as well as others involved in research in this area, such as research clinicians.

Key Features

  • Examines the diverse range and use of hydrogels, focusing on processing methods and novel applications
  • Comprehensive book explores the structure and properties of hydrogels and different fabrication technologies
  • Covers important areas such as processing of hydrogels, covering hydrogel swelling behaviour, superabsorbent cellulose-based hydrogels and regulation of novel hydrogel products

Readership

Biomedical research scientists and engineers in industry and academia as well as others involved in research in this area, such as research clinicians

Table of Contents

Contributor contact details

Part I: Processing of hydrogels

Chapter 1: Hydrogel swelling behavior and its biomedical applications

Abstract:

1.1 Basics of hydrogels

1.2 Swelling of hydrogels: water diffusion into hydrogels

1.3 Stimulus-responsive hydrogels

1.4 Examples of environment-sensitive hydrogels

1.5 Future trends

Chapter 2: Superabsorbent cellulose-based hydrogels for biomedical applications

Abstract:

2.1 Introduction

2.2 Cellulose-based hydrogels and crosslinking strategies

2.3 Hydrogel properties and thermodynamics

2.4 Applications

2.5 Conclusions

Chapter 3: Synthesis of hydrogels for biomedical applications: control of structure and properties

Abstract:

3.1 Introduction

3.2 Cross-linking of high molecular weight polymers

3.3 Copolymerization with multi-functional monomers

3.4 Multiphase hydrogels

3.5 Functional hydrogels

3.6 Conclusion

Chapter 4: Processing and fabrication technologies for biomedical hydrogels

Abstract:

4.1 Introduction

4.2 Applications

4.3 Gelation

4.4 Physical crosslinking

4.5 Photopolymerization and photopatterning

4.6 Stereolithography

4.7 Two-photon laser scanning photolithography

4.8 Processing of multicomponent hydrogels

4.9 Future trends

4.10 Acknowledgements

Chapter 5: Regulation of novel biomedical hydrogel products

Abstract:

5.1 Introduction

5.2 Regulatory jurisdictions

5.3 Regulatory frameworks

5.4 Risk-based device classification

5.5 Non-clinical testing

5.6 Clinical data and studies

5.7 Marketing authorization processes

5.8 Quality system requirements

5.9 Post-market requirements

5.10 Future trends

5.11 Sources of further information and advice

Details

No. of pages:
288
Language:
English
Copyright:
© 2011
Published:
Imprint:
Woodhead Publishing
eBook ISBN:
9780857091383
Print ISBN:
9781845695903
Print ISBN:
9780081017418

About the editor

Steve Rimmer

Steve Rimmer is a Senior Lecturer in the Department of Chemistry at Sheffield University.

Affiliations and Expertise

University of Sheffield, UK

Reviews

"…the book is the perfect lead for researchers interested in hydrogels to be applied for biomedical purposes. It offers a comprehensive overview of the complete route a hydrogel should follow going from developmental stage to clinical application and legislation."--Biomat.net, March 2014