Biomedical Foams for Tissue Engineering Applications

Biomedical Foams for Tissue Engineering Applications

1st Edition - February 17, 2014

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  • Editor: Paulo Netti
  • eBook ISBN: 9780857097033

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Description

Biomedical foams are a new class of materials, which are increasingly being used for tissue engineering applications. Biomedical Foams for Tissue Engineering Applications provides a comprehensive review of this new class of materials, whose structure can be engineered to meet the requirements of nutrient trafficking and cell and tissue invasion, and to tune the degradation rate and mechanical stability on the specific tissue to be repaired. Part one explores the fundamentals, properties, and modification of biomedical foams, including the optimal design and manufacture of biomedical foam pore structure for tissue engineering applications, biodegradable biomedical foam scaffolds, tailoring the pore structure of foam scaffolds for nerve regeneration, and tailoring properties of polymeric biomedical foams. Chapters in part two focus on tissue engineering applications of biomedical foams, including the use of bioactive glass foams for tissue engineering applications, bioactive glass and glass-ceramic foam scaffolds for bone tissue restoration, composite biomedical foams for engineering bone tissue, injectable biomedical foams for bone regeneration, polylactic acid (PLA) biomedical foams for tissue engineering, porous hydrogel biomedical foam scaffolds for tissue repair, and titanium biomedical foams for osseointegration. Biomedical Foams for Tissue Engineering Applications is a technical resource for researchers and developers in the field of biomaterials, and academics and students of biomedical engineering and regenerative medicine.

Key Features

  • Explores the fundamentals, properties, and modification of biomedical foams
  • Includes intense focus on tissue engineering applications of biomedical foams
  • A technical resource for researchers and developers in the field of biomaterials, and academics and students of biomedical engineering and regenerative medicine

Readership

Researchers active in the fields of chemistry, polymer development, materials processing, biology, medicine, and tissue engineering; Manufacturers and developers of bone substitutes based on bioceramics and bioglasses; Academics in biomedical engineering and regenerative medicine

Table of Contents

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    Woodhead Publishing Series in Biomaterials

    Part I: Fundamentals, properties and modification of biomedical foams

    1. Introduction to biomedical foams

    Abstract:

    1.1 Introduction

    1.2 Evolution of biomedical foams

    1.3 Materials for fabricating biomedical foams

    1.4 Manufacturing processes for biomedical foams and scaffolds

    1.5 Scaffolds for in vitro cell culture

    1.6 Scaffolds for in vivo tissue-induced regeneration

    1.7 Platforms for the controlled delivery of bioactive agents

    1.8 Microscaffolds for in situ cell delivery and tissue fabrication

    1.9 Three-dimensional tumour models

    1.10 Conclusion

    1.11 References

    2. Properties of biomedical foams for tissue engineering applications

    Abstract:

    2.1 Introduction

    2.2 Metals for biomedical foam fabrication

    2.3 Ceramics and glass for biomedical foam fabrication

    2.4 Degradable polymers for biomedical foam fabrication

    2.5 Polymer-based composites for biomedical foam fabrication

    2.6 Conclusions and future trends

    2.7 References

    3. Optimal design and manufacture of biomedical foam pore structure for tissue engineering applications

    Abstract:

    3.1 Introduction

    3.2 Micro-structure of biomedical foams and processing techniques

    3.3 Improving control of scaffold pore structure by combined approaches

    3.4 Pore structure versus in vitro cell culture

    3.5 Pore structure vs. in vivo new tissue regeneration

    3.6 Conclusion

    3.7 References

    4. Tailoring the pore structure of foam scaffolds for nerve regeneration

    Abstract:

    4.1 Introduction

    4.2 Materials for foam scaffold fabrication

    4.3 Design and fabrication of foam scaffolds for nerve regeneration

    4.4 Methods of assessing nerve regeneration and overview of porous scaffolds

    4.5 Future trends

    4.6 Conclusion

    4.7 References

    5. Tailoring properties of polymeric biomedical foams

    Abstract:

    5.1 Introduction

    5.2 Aliphatic polyesters used for porous scaffold fabrication

    5.3 Polyurethanes for biomedical foam production

    5.4 Tyrosine-derived polymers

    5.5 Processing techniques for fabricating porous scaffolds

    5.6 Characterization of polymeric foams

    5.7 In vitro and in vivo testing

    5.8 Applications of polymeric foams in tissue engineering

    5.9 Future trends

    5.10 Sources of further information and advice

    5.11 References

    6. Biodegradable biomedical foam scaffolds

    Abstract:

    6.1 Introduction

    6.2 Foaming techniques and properties of expanding polymer/gas solutions

    6.3 Biofoams based on natural polymers

    6.4 Biofoams based on biodegradable polyesters

    6.5 References

    Part II: Tissue engineering applications of biomedical foams

    7. Bioactive glass foams for tissue engineering applications

    Abstract:

    7.1 Introduction

    7.2 Processing ‘foam-like’ bioactive glass-based scaffolds

    7.3 In vitro and in vivo studies of bioactive glass-based biomedical foams

    7.4 Conclusions and future trends

    7.5 References

    8. Bioactive glass and glass–ceramic foam scaffolds for bone tissue restoration

    Abstract:

    8.1 Introduction

    8.2 The potential of bioactive glass and the bioactivity mechanism

    8.3 Processing, 3-D architecture and mechanical properties of glass foams

    8.4 In vitro and in vivo behaviour

    8.5 Current clinical applications

    8.6 Future trends

    8.7 References

    9. Composite biomedical foams for engineering bone tissue

    Abstract:

    9.1 Introduction

    9.2 Chemical and morphological biomimesis: the key for osteointegration

    9.3 Foaming: an approach to fabricate highly porous bioactive scaffolds

    9.4 Freeze-dried hybrid gels for bone and osteochondral regeneration

    9.5 In vivo performances of bioactive foams with defined morphology and microstructure

    9.6 Future trends

    9.7 Conclusion

    9.8 References

    10. Injectable biomedical foams for bone regeneration

    Abstract:

    10.1 Introduction

    10.2 Injectable calcium phosphate foams

    10.3 Porosity and mechanical performance of calcium phosphate foams

    10.4 Injectability and cohesion of calcium phosphate foams

    10.5 In vitro and in vivo response to injectable calcium phosphate foams

    10.6 Applications of injectable calcium phosphate foams

    10.7 Conclusion and future trends

    10.8 Sources of further information and advice

    10.9 Acknowledgments

    10.10 References

    11. Polylactic acid (PLA) biomedical foams for tissue engineering

    Abstract:

    11.1 Introduction

    11.2 Polylactic acid (PLA)

    11.3 Fabrication of PLA foams

    11.4 Gas foaming using supercritical CO2 (scCO2)

    11.5 Solid-state foaming with high pressure CO2

    11.6 Tissue engineering applications of PLA and PLA-based foams

    11.7 Conclusion and future trends

    11.8 References

    12. Porous hydrogel biomedical foam scaffolds for tissue repair

    Abstract:

    12.1 Introduction

    12.2 Hydrogel foam materials

    12.3 Equilibrium swelling theory and rubber elasticity theory

    12.4 Overview of hydrogel properties

    12.5 Natural hydrogel materials

    12.6 Hydrogel foam processing technologies

    12.7 Electrospinning and rapid prototyping

    12.8 Characterization of hydrogel foams

    12.9 Future trends

    12.10 References

    13. Titanium biomedical foams for osseointegration

    Abstract:

    13.1 Introduction: Titanium for biomedical applications

    13.2 Titanium foam processing and surface treatments

    13.3 Bio-activation of titanium surfaces

    13.4 Bone interactions at the bio-interface

    13.5 Future trends

    13.6 Sources of further information and advice

    13.7 References

    Index

Product details

  • No. of pages: 446
  • Language: English
  • Copyright: © Woodhead Publishing 2014
  • Published: February 17, 2014
  • Imprint: Woodhead Publishing
  • eBook ISBN: 9780857097033

About the Editor

Paulo Netti

Paolo A. Netti is a Professor of Material Science at the Department of Chemical, Materials and Production Engineering, University of Naples Federico II, Italy and the Director of the Centre for Advanced Biomaterials for Health Care of the Istituto Italiano di Tecnologia.

Affiliations and Expertise

Professor of Material Science, Department of Chemical, Materials and Production Engineering, University of Naples, Italy

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