Description

There have been important developments in materials and therapies for the treatment of spinal conditions. Biomaterials for spinal surgery summarises this research and how it is being applied for the benefit of patients.

After an introduction to the subject, part one reviews fundamental issues such as spinal conditions and their pathologies, spinal loads, modelling and osteobiologic agents in spinal surgery. Part two discusses the use of bone substitutes and artificial intervertebral discs whilst part three covers topics such as the use of injectable biomaterials like calcium phosphate for vertebroplasty and kyphoplasty as well as scoliosis implants. The final part of the book summarises developments in regenerative therapies such as the use of stem cells for intervertebral disc regeneration.

With its distinguished editors and international team of contributors, Biomaterials for spinal surgery is a standard reference for both those developing new biomaterials and therapies for spinal surgery and those using them in clinical practice.

Key Features

  • Summarises recent developments in materials and therapies for the treatment of spinal conditions and examines how it is being applied for the benefit of patients
  • Reviews fundamental issues such as spinal conditions and their pathologies, spinal loads, modelling and osteobiologic agents in spinal surgery
  • Discusses the use of bone substitutes and artificial intervertebral discs and covers topics such as the use of injectable biomaterials like calcium phosphate for vertebroplasty and kyphoplasty

Readership

Materials scientists and engineers in industry, biologists and clinicians, biomaterials academics and orthopedic surgeons.

Table of Contents

Contributor contact details

Chapter 1: Introduction to biomaterials for spinal surgery

Abstract:

1.1 Introduction

1.2 Total disc replacement

1.3 Nucleus pulposus replacement

1.4 Materials for spinal applications

1.5 Conclusions

Part I: Fundamentals of biomaterials for spinal surgery

Chapter 2: An overview of the challenges of bringing a medical device for the spine to the market

Abstract:

2.1 Introduction

2.2 Selection and sourcing of materials in medical device developments

2.3 Biocompatibility testing

2.4 Medical device regulation

2.5 Conclusions

2.6 Acknowledgement

Chapter 3: Introduction to spinal pathologies and clinical problems of the spine

Abstract:

3.1 Introduction

3.2 Degenerative spine disease

3.3 Spinal trauma

3.4 Spinal deformity

3.5 Malignancy

3.6 Infection

3.7 Conclusions

Chapter 4: Forces on the spine

Abstract:

4.1 Introduction

4.2 In vivo measured components of spinal loads

4.3 In vitro measured spinal load components

4.4 Analytical models for spinal load estimation

4.5 Recommendations for the simulations of loads for in vitro and numerical studies

4.6 Conclusions

Chapter 5: Finite element modelling of the spine

Abstract:

5.1 Introduction

5.2 Functional spine biomechanics and strength of numerical explorations

5.3 Geometrical approximations in spine finite element modelling

5.4 Numerical approximations: accuracy and computational cost

5.5 Constitutive models for the spine tissues

5.6 Simulating the mechanical loads on the spine

5.7 Model verifications and interpretations: the validation concept and quantitative validation

5.8 Future trends and conclusions: the virtual physiological spine

Chapter 6:

Details

No. of pages:
640
Language:
English
Copyright:
© 2012
Published:
Imprint:
Woodhead Publishing
Electronic ISBN:
9780857096197
Print ISBN:
9781845699864

About the editors

Elizabeth Tanner

Elizabeth Tanner is Professor of Mechanics of Materials and Structures at the University of Glasgow, UK. Both are noted for their research in bone biomaterials and therapies.

Reviews

This is a good reference on biomaterials. It will be of most interest to materials engineers, bioengineers and spine surgeons. It is well written and provides an extensive list of references., Doody's Book Reviews