Biomaterials for 3D Tumor Modeling

1. Trends in biomaterials for 3D cancer modeling
2. Causes of cancers: physical, chemical, biological carcinogens and viruses
3. Three-dimensional in vitro models of angiogenesis
4. Metastasis in 3D biomaterials
5. Biomatrices that mimic the cancer extracellular environment
6. Marine derived biomaterials for cancer treatment
7. 3D scaffold materials for skin cancer modeling
8. Three-dimensional tumor model and their implication in drug screening for tackling chemoresistance
9. In vitro 3D modelling for prostate cancer
10. Biomaterial based in vitro models for pancreatic cancer
11. Mesoporous silica nanoparticles for cancer theranostics applications
12. Microfluidic systems in cancer research
13. Bio-detection and sensing for cancer diagnostics
14. Biomaterials as ECM-like matrices for 3D in vitro tumor models
15. 3D cancer spheroids and microtissues
16. Co-culture and 3D tumor models for drug and gene therapy testing
17. Engineering of 3D in vitro models for cancer research
18. Tissue engineered 3D cancer microenvironment for screening therapeutics
19. 3D neuroblastoma models using engineered cell-derived matrices
20. 3D cancer models for chemotherapy using biomaterials
21. 3D tumor-on-chip devices with perfusion for anti-cancer drug testing
22. A predictive oncology framework: Modelling tumor proliferation using a FEM platform
23. Understanding the impact of controlled oxygen delivery to 3D cancer cell culture
24. 3D full skin models for skin cancer research
25. Tissue engineering strategies for treatment of skeletal maxillofacial defects resulting from neoplasms resections
26. 3D culture systems as models for solid tumors and cancer metabolism
27. Biofabrication of 3D tumor models in cancer research
28. Engineering breast cancer models in vitro with 3D printing

Biomaterials for 3D Tumor Modeling reviews the fundamentals and most relevant areas of the latest advances of research of 3D cancer models, focusing on biomaterials science, tissue engineering, drug delivery and screening aspects. The book reviews advanced fundamental topics, including the causes of cancer, existing cancer models, angiogenesis and inflammation during cancer progression, and metastasis in 3D biomaterials. Then, the most relevant biomaterials are reviewed, including methods for engineering and fabrication of biomaterials. 3D models for key biological systems and types of cancer are also discussed, including lung, liver, oral, prostate, pancreatic, ovarian, bone and pediatric cancer.

This book is suitable for those working in the disciplines of materials science, biochemistry, genetics, molecular biology, drug delivery and regenerative medicine.

• Reviews key biomaterials topics, including synthetic biomaterials, hydrogels, e-spun materials and nanoparticles
• Provides a comprehensive overview of 3D cancer models for key biological systems and cancer types
• Includes an overview of advanced fundamental concepts for an interdisciplinary audience in materials science, biochemistry, regenerative medicine and drug delivery

Materials Scientists, those working in Regenerative Medicine, those working in Biochemistry, those working in drug delivery, academics and those working in the clinic