Description

Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia.

Key Features

Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research
Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Readership

Neuroscientists, neurologists, psychologists

Table of Contents

Series Page

Contributors

Preface

General overview

I. The Quest for Biomarkers in Neuroscience

II. Tools for Biomarker Discovery in Neuroscience

III. Advancements in Biomarker Discovery in Neuroscience

IV. Considerations for Biomarker Discovery and Translation in Neuroscience

V. Outlook—The Perspective of Personalized Medicine

Acknowledgments

Imaging Brain Microglial Activation Using Positron Emission Tomography and Translocator Protein-Specific Radioligands

I. Introduction

II. Principles of PET Imaging

III. TSPO for Assessment of Microglial Expression

IV. Challenges Facing PET Imaging of the TSPO

V. Disease Applications

VI. Conclusion

Acknowledgments

The Utility of Gene Expression in Blood Cells for Diagnosing Neuropsychiatric Disorders

I. Introduction

II. Microarray Gene Expression Analysis

III. Diagnostic Gene Expression Classifiers

IV. Blood Gene Expression Studies of Neuropsychiatric Disorders

V. MicroRNA Expression Analysis

VI. Pharmacogenomics

VII. Concluding Remarks

Acknowledgments

Proteomic Technologies for Biomarker Studies in Psychiatry

Abbreviations

I. Introduction

II. The Social Impact of Psychiatric Disorders

III. The Role of Proteomics in Psychiatry

IV. Proteomic Studies in Psychiatry: What Methods Have Been Used to Date?

V. Underexplored Proteomic Methods in Psychiatry Studies

VI. The Importance of Validation Experiments in Proteomics for Biomarker Discovery in Psychiatry

VII. Clinical Translation

VIII. Summary

Acknowledgments

Converging evidence of blood-based biomarkers for schizophrenia

I. Introduction

II. Methodology

III. Results

IV. Discussion

V. C

Details

No. of pages:
470
Language:
English
Copyright:
© 2011
Published:
Imprint:
Academic Press
Print ISBN:
9780123877185
Electronic ISBN:
9780123877239

Reviews

"Invaluable reading." - NATURE
"A valuable addition to any library as current reference material for advanced undergraduates, graduate students, and professional scientists."
- CHOICE