Biomarkers of Neurological and Psychiatric Disease, Volume 101

1st Edition

Serial Volume Editors: Sabine Bahn Paul Guest
Hardcover ISBN: 9780123877185
eBook ISBN: 9780123877239
Imprint: Academic Press
Published Date: 9th November 2011
Page Count: 470
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Table of Contents

Series Page



General overview

I. The Quest for Biomarkers in Neuroscience

II. Tools for Biomarker Discovery in Neuroscience

III. Advancements in Biomarker Discovery in Neuroscience

IV. Considerations for Biomarker Discovery and Translation in Neuroscience

V. Outlook—The Perspective of Personalized Medicine


Imaging Brain Microglial Activation Using Positron Emission Tomography and Translocator Protein-Specific Radioligands

I. Introduction

II. Principles of PET Imaging

III. TSPO for Assessment of Microglial Expression

IV. Challenges Facing PET Imaging of the TSPO

V. Disease Applications

VI. Conclusion


The Utility of Gene Expression in Blood Cells for Diagnosing Neuropsychiatric Disorders

I. Introduction

II. Microarray Gene Expression Analysis

III. Diagnostic Gene Expression Classifiers

IV. Blood Gene Expression Studies of Neuropsychiatric Disorders

V. MicroRNA Expression Analysis

VI. Pharmacogenomics

VII. Concluding Remarks


Proteomic Technologies for Biomarker Studies in Psychiatry


I. Introduction

II. The Social Impact of Psychiatric Disorders

III. The Role of Proteomics in Psychiatry

IV. Proteomic Studies in Psychiatry: What Methods Have Been Used to Date?

V. Underexplored Proteomic Methods in Psychiatry Studies

VI. The Importance of Validation Experiments in Proteomics for Biomarker Discovery in Psychiatry

VII. Clinical Translation

VIII. Summary


Converging evidence of blood-based biomarkers for schizophrenia

I. Introduction

II. Methodology

III. Results

IV. Discussion

V. C


Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia.

Key Features

  • Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research
  • Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
  • All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist


Neuroscientists, neurologists, psychologists


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© Academic Press 2011
Academic Press
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"Invaluable reading." --Nature

"A valuable addition to any library as current reference material for advanced undergraduates, graduate students, and professional scientists." --Choice

About the Serial Volume Editors

Sabine Bahn Serial Volume Editor

Paul Guest Serial Volume Editor