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Biologics for the Treatment of Allergic Diseases, An Issue of Immunology and Allergy Clinics of North America
- 1st Edition, Volume 40-4 - October 12, 2020
- Editor: Lanny J. Rosenwasser
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 7 7 7 3 0 - 8
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 7 7 7 3 1 - 5
This issue of Immunology and Allergy Clinics, guest edited by Dr. Lanny Rosenwasser, will provide up-to-date clinical concepts regarding Biologics for the Treatments of Allergic… Read more
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Request a sales quoteThis issue of Immunology and Allergy Clinics, guest edited by Dr. Lanny Rosenwasser, will provide up-to-date clinical concepts regarding Biologics for the Treatments of Allergic Conditions. Articles in this outstanding issue include: Allergic Rhinitis/CRS/Polyposis, Eosinophilic Asthma, Pediatric Asthma, Severe Asthma, ACOS/COPD, Food Allergy, Atopic Dermatitis, Chronic Urticaria, Anaphylaxis, Drug Allergy, Cell Disorders, Biologics and Immunotherapy, and much more.
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Immunology and Allergy Clinics of North America
- Preface
- Biologics for the Treatment of Allergic Rhinitis, Chronic Rhinosinusitis, and Nasal Polyposis
- Key points
- Introduction
- Biologics in the treatment of allergic rhinitis
- Chronic rhinosinusitis without nasal polyps
- Biologics for nasal polyposis
- Summary
- Clinics care points
- Biologics for the Treatments of Allergic Conditions: Severe Asthma
- Key points
- Introduction
- Biologics for severe asthma: what’s on
- Biologics for severe asthma: the near future
- Real-life perspective: rationale and major evidence
- Summary and unmet needs
- Clinics care points
- Asthma-Chronic Obstructive Pulmonary Disease Overlap
- Key points
- Diagnostic criteria
- Epidemiology
- Risk factors
- Natural history of asthma-chronic obstructive pulmonary disease overlap
- Biological determinants and biomarkers of asthma-chronic obstructive pulmonary disease overlap
- Possible therapeutic options
- Summary
- Clinics care points
- Biologics for the Treatment of Food Allergies
- Key points
- Introduction
- Biologics in atopic conditions
- Biologics in food allergy
- Anti-IgE monotherapy for food allergy
- Omalizumab as an adjunct to peanut oral immunotherapy
- Omalizumab as an adjunct to milk and egg oral immunotherapy
- Omalizumab as an adjunct to multifood oral immunotherapy
- Additional biologic therapies
- Potential future targets
- Summary
- Clinic care points
- Biologics for Atopic Dermatitis
- Key points
- Introduction
- Rationale for biologic therapy in atopic dermatitis
- Which patients with atopic dermatitis warrant therapy with a biologic?
- Historical perspective on biotherapeutics in atopic dermatitis
- Currently approved biologic
- Off-label use of biologic for atopic dermatitis
- Biologics undergoing evaluation in atopic dermatitis
- Summary
- Clinical care points
- Current and Potential Biologic Drugs for the Treatment of Chronic Urticaria
- Key points
- Introduction
- Pathogenesis of chronic spontaneous urticaria
- Biologic medications for chronic spontaneous urticaria
- Other biologics potentially useful for the treatment of chronic urticaria
- Additional therapeutic targets
- Summary
- Clinics care points
- Biologic Agents for the Treatment of Anaphylaxis
- Key points
- Anaphylaxis: a high-priority public health issue that requires immediate treatment and preventive measures
- Is there a place for biologic agents in anaphylaxis treatment?
- Biologic agents and anaphylaxis
- Clinics care points
- Immune-Related Adverse Drug Reactions and Immunologically Mediated Drug Hypersensitivity
- Key points
- Introduction
- Definitions
- Background
- History
- Epidemiology
- Mast cell activation
- Small molecules
- Human and humanized proteins
- Xenogeneic proteins
- Confirming immunologically mediated hypersensitivity
- Managing patients with historical reactions without testing or rechallenge
- Desensitizations
- Blocking new immune reactions
- Pathologic immune activation
- Pathologic immune suppression
- Summary
- Clinical care points
- Biologics for the Treatment of Allergic Conditions: Eosinophil Disorders
- Key points
- Introduction
- Conclusion
- Clinics care points
- Targeting Mast Cells with Biologics
- Key points
- Introduction
- Role of mast cells in allergic diseases and reactions
- Clonal and nonclonal mast cell–associated disorders
- Allergen immunotherapy: the first mast cell targeting biologic
- Biologics targeting mast cell proliferation and effector function
- Biologics targeting neoplastic mast cells
- Discussion
- Summary
- Clinical care points
- Biologics and Allergy Immunotherapy in the Treatment of Allergic Diseases
- Key points
- Introduction
- Targeted biological therapies
- Summary: practical considerations and unmet needs
- Clinics care points
- No. of pages: 240
- Language: English
- Edition: 1
- Volume: 40-4
- Published: October 12, 2020
- Imprint: Elsevier
- Hardback ISBN: 9780323777308
- eBook ISBN: 9780323777315
LR
Lanny J. Rosenwasser
Affiliations and expertise
Past President, American Academy of Allergy, Asthma, and Immunology
Professor of Medicine
University of Missouri-Kansas City School of Medicine