Biological Oxidation Systems V1 - 1st Edition - ISBN: 9780125845519, 9780323145749

Biological Oxidation Systems V1

1st Edition

Editors: C.C. Reddy
eBook ISBN: 9780323145749
Imprint: Academic Press
Published Date: 28th August 1990
Page Count: 568
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Description

Biological Oxidation Systems, Volume I is a collection of papers presented at the 1989 Bangalore Symposium on Oxygen Systems. This symposium covers various research studies on the essential roles, and the dangers of dioxygen reactions in biology.

This volume is organized into five parts encompassing 32 chapters, and starts with an overview of the biological oxidation mechanisms involving oxygen and reduced oxygen derivatives. Parts I and II deal with the catalytic role of cytochrome P-450 and oxidase and oxygenase containing a flavin or pteridine enzymes in several biological oxidation reactions. These parts examine the biochemical aspects, reaction kinetics, and reaction mechanisms of such reactions. Parts III and IV describe first the structure function and properties of copper-containing oxidases and oxygenases. These parts also discuss the role of nonheme iron-containing and other oxygenases in the indole metabolism. Part V focuses on the role of peroxidase enzymes in cell protection and metabolism.

This book will prove useful to biologists, enzyme scientists, and researchers.

Table of Contents


Contents Volume 2


Foreword


Preface


Sponsors


Overview: Mechanisms of Biological Oxidations


Mechanisms of Biological Oxidation Reactions Involving Oxygen and Reduced Oxygen Derivatives


I. Cytochrome P-450 Catalyzed Reactions


The Cytochrome P-450 Superfamily: Impact on Biology and Medicine


Transcriptional Regulation of Cytochrome P-450b/e Gene Expression in Rat Liver


Oxidation Reactions Catalyzed by Cytochrome P-450 Enzymes


Cellular Responses To Oxidative Stress


Abberations in Cytochrome P-450 and Mixed Function Oxidase System


Preferential Induction of Biological Oxidation Systems in Alkaloid Metabolism of Plant Tissues Cultures Subjected to Fungal Elicitation


(+)-Pulegone Mediated Hepatotoxicity in Rat; Role of Microsomal Cytochrome P-450


Cytochrome P-450 Catalyzed Reactions in Brain


Microsomal Cytochrome P-450 Mediated N-Oxygenation of Amino Azaheterocycles


Presence of Phenobarbital and 3-Methylcholanthrene Inducible Forms of Cytochrome P-450 in Rat Brain


Recriprocal Post-Translational Regulation of Chick Kidney Mitochondrial 1α- and 24R-Hydroxylase of 25-Hydroxyvitamin D3


Cytoprotective Mechanisms that Offset the Potential Augmentation of Phenobarbital-Induced 02-∙ Generation During Quinone Recylcling


II. Oxidases and Oxygenases Containing a Flavin/Pteridine


Studies on the Mechanism of the Uncoupled Reaction Catalyzed by Rat Liver Phenylalanine Hydroxylase


Why is the Cofactor for the Tetrahydrobiopterin Dependent Monooxygenases not a Dihydroflavin?


Biochemical Aspects of Molybdopterin


The Kinetics and Regulation of Aromatic Amino Acid Hydroxylases: The Effect of Cofactor Structure


The Mechanism of Oxygen Activation by Flavoprotein Monooxygenase


III. Cop

Details

No. of pages:
568
Language:
English
Copyright:
© Academic Press 1990
Published:
Imprint:
Academic Press
eBook ISBN:
9780323145749

About the Editor

C.C. Reddy

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