Biological Functions of Microtubules and Related Structures

Biological Functions of Microtubules and Related Structures

1st Edition - January 1, 1982

Write a review

  • Editors: Hikoichi Sakai, Hideo Mohri, Gary G. Borisy
  • eBook ISBN: 9781483272207

Purchase options

Purchase options
DRM-free (PDF)
Sales tax will be calculated at check-out

Institutional Subscription

Free Global Shipping
No minimum order

Description

Biological Functions of Microtubules and Related Structures is a compendium of papers presented at the 13th Oji International Seminar on The Biological Functions of Microtubules and Related Structures, held at Komaba Eminence in Tokyo in November, 1981. The papers discuss the molecular function of tubulin in various biological processes or events. The book is divided into six sections focusing on the various aspects of the functions and structures of microtubules -- the biochemistry and molecular biology of tubulin, including regulation of microtubule assembly; microtubule-dynein systems and other proteins in cell motility; microtubules and related proteins in mitosis; the interactions of cytoskeletal components; the cytoskeleton; and microtubules in membrane functions and transport. Biochemists, biologists, and molecular biologists will find the book interesting.

Table of Contents


  • Contents

    Contributors

    Preface

    Acknowledgments

    I Tubulin and Microtubules; Biochemistry, Molecular Biology, and Regulation of Assembly

    1. Tubulin and Tubulin-Associated CDR-Like Protein from Azuki Bean Epicotyls

    2. Purification and Properties of Microtubule-Associated ATPases from Bovine Brain

    3. Fractionation and Electrophoretic Analysis of Microtubule Proteins from Rat Brain

    4. Detection of Tubulin Genes in Yeasts

    5. Flexural Rigidity of Singlet Microtubules Estimated from Statistical Analysis of Fluctuating Images

    6. Evaluation of Potential Roles for GDP in Microtubule Assembly and Disassembly

    7. Interaction of Vinblastine with Steady-State Microtubules in Vitro: Mechanism of Inhibition of Net Tubulin Addition to Assembly Ends

    8. Quantitative Analysis of Association of Calmodulin with Tubulin

    9. Ca2+- and Calmodulin-Dependent Flip-Flop Mechanism in the Regulation of Microtubule Assembly-Disassembly

    II Dynein, Microtubules, and Other Proteins in Cell motility

    10. Intra-Axopodial Particle Movement and Axopodial Surface Motility in Echinosphaerium akamae

    11. Rapid Contraction of the Microtubule-Containing Axopodia in a Large Heliozoan E chinosphaerium

    12. Calmodulin in the Cilia of Tetrahymena

    13. Molecular Composition and Structure of Dynein Arms

    14. Dynein and Its Role in Cell Motility

    15. Cyclic AMP and Initiation of Flagellar Movement in Rainbow Trout Spermatozoa

    16. Involvement of Cyclic AMP-Dependent Protein Kinase and a Protein Factor in the Regulation of the Motility of Sea Urchin and Starfish Spermatozoa

    17. The Dynamics of Microtubule Sliding in Flagella

    18. Rotation of the Central-Pair Microtubules in Chlamydomonas Flagella

    III Microtubules and Related Proteins in Mitosis

    19. Localization of Fluorescently Labeled Calmodulin in Living Sand Dollar Eggs during Early Development

    20. Analysis of D20-Effect on in Vivo and in Vitro Tubulin Polymerization and Depolymerization

    21. Spindle Structure after Chromosome Micromanipulation

    22. Mechanics of Anaphase B Movement

    23. Location of the Motive Force for Chromosome Movement in Sand Dollar Eggs

    IV Interactions of Cytoskeletal Components

    24. Assembly and Disassembly of Echinoderm Egg Actin

    25. Capping, Bundling, Crosslinking Three Properties of Actin Binding Proteins

    26. Phosphorylation of Microtubule-Associated Proteins (MAPs)Controls Both Microtubule Assembly and MAPs-Actin Interaction

    27. The Association of MAP-2 with Microtubules, Actin Filaments, and Coated Vesicles

    28. Actin-Microtubule Interactions

    V Cytoskeletons

    29. On the Coexistence of Glial Fibrillary Acidic (GFA) Protein and Vimentin in Astroglial Filaments

    30. The Microtubule-Neurofilament Network: The Balance between Plasticity and Stability in the Nervous System

    31. The Cytoskeleton in Myelinated Axons

    VI Microtubules in Membrane Functions and Transport

    35. Microtubules Composed of Tyrosinated Tubulin Are Required for Membrane Excitability in Squid Giant Axon

    36. New Roles for Tubulin in Membrane Function

    37. Fast Axoplasmic Transport of a Calmodulin-Related Polypeptide

    38. A Permeabilized Model of Pigment Particle Translocation: Evidence for the Involvement of a Dynein-Like Molecule in Pigment Aggregation

    Author Index

    Subject Index


Product details

  • No. of pages: 474
  • Language: English
  • Copyright: © Academic Press 1982
  • Published: January 1, 1982
  • Imprint: Academic Press
  • eBook ISBN: 9781483272207

About the Editors

Hikoichi Sakai

Hideo Mohri

Gary G. Borisy

Ratings and Reviews

Write a review

There are currently no reviews for "Biological Functions of Microtubules and Related Structures"