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Bioinformatics - 1st Edition - ISBN: 9780323897754


1st Edition

Methods and Applications

Editors: Dev Singh Rajesh Pathak
Paperback ISBN: 9780323897754
Imprint: Academic Press
Published Date: 1st September 2021
Page Count: 400
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Bioinformatics: Methods and Applications provides a thorough and detailed description of principles, methods, and applications of bioinformatics in different areas of life sciences. It presents a compendium of many important topics of current advanced research and basic principles/approaches easily applicable to diverse research settings.
The content encompasses topics such as biological databases, sequence analysis, genome assembly, RNA sequence data analysis, drug design, and structural and functional analysis of proteins. In addition, it discusses computational approaches for vaccine design, systems biology and big data analysis, and machine learning in bioinformatics.

It is a valuable source for bioinformaticians, computer biologists, and members of biomedical field who needs to learn bioinformatics approaches to apply to their research and lab activities.

Key Features

  • Covers basic and more advanced developments of bioinformatics with a diverse and interdisciplinary approach to fulfill the needs of readers from different backgrounds
  • Explains in a practical way how to decode complex biological problems using computational approaches and resources
  • Brings case studies, real-world examples and several protocols to guide the readers with a problem-solving approach


Graduate students of bioinformatics; biomedical researchers in general

Table of Contents

  1. Introduction to Basics of Bioinformatics
    2. Biological Databases and their Applications
    3. Biological Sequence Analysis
    4. Genome Assembly and Annotation
    5. Molecular Phylogeny and its Applications
    6. Applications and challenges of transcriptome analysis: From microarray to next-generation sequencing
    7. RNAseq Data Analysis
    8. Analysis of SSR and SNP Markers
    9. Gene Ontology (GO) Enrichment Analysis
    10. Bioinformatics the boon for cracking current challenges in metagenome analysis
    11. Protein structure Prediction
    12. Structural and Functional analysis of protein
    13. Computational Approaches in Drug designing
    14. Structure-Based Drug Designing
    15. Ligand-Based Drug Designing
    16. Lead discovery and Lead Optimization
    17. Pharmacophore modeling and its applications
    18. Molecular Docking and molecular Dynamics Simulation
    19. Pharmacokinetics and Pharmacodynamics analysis of Drug Candidates
    20. Computational Approaches for Vaccine Designing
    21. Metabolomics and Metabolic Flux Analysis
    22. Network Biology and its Applications
    23. Pathway Modeling and Simulation Analysis
    24. Systems Biology and Big data Analysis
    25. Machine Leaning in Bioinformatics
    26. Bioinformatics and Biological Data mining


No. of pages:
© Academic Press 2021
1st September 2021
Academic Press
Paperback ISBN:

About the Editors

Dev Singh

Dev Singh

He graduated in Biology (BSc), MSc (Bioinformatics) and PhD (Biotechnology) at University of Allahabad and MTech (Bioinformatics) at Indian Institute of Information Technology. He has been actively involved in teaching and research since 2009, is teaching bioinformatics and biostatistics courses to BSc (Hons) and MSc Biotechnology students and his areas of research are molecular modeling, chemo-informatics, inhibitors/drug designing, in silico evaluation and in vitro testing. He is associated with many international educational societies such as Bioinformatics organization, Nexxus Foundation (Scotland), Bioinformatics Society (International Association of Engineers) and Indian Science Congress Association. He is editor-in-chief of Translational Medicine journal, member of advisory board of Cambridge Scholars Publishing and author of two books: ‘Frontiers in Protein Structure, Function, and Dynamics’ and ‘Computer-Aided Drug Design’ (both Springer). Dev Bukhsh Singh, MSc, MTech, PhD, is Assistant Professor at Department of Biotechnology, Institute of Biosciences and Biotechnology, Chhatrapati Shahu Ji Maharaj University.

Affiliations and Expertise

Assistant Professor, Department of Biotechnology, Institute of Biosciences and Biotechnology, Chhatrapati Shahu Ji Maharaj University, India

Rajesh Pathak

Rajesh Pathak

Rajesh Kumar Pathak, PhD, completed his BSc (Biotechnology) at Barkatullah University, MSc (Bioinformatics) at Chhatrapati Shahu Ji Maharaj University, and PhD at G. B. Pant Institute of Engineering & Technology. His research interests lie in the areas of the genome and transcriptome assembly and annotation, microarray data analysis, pathway modeling, network analysis, molecular docking, virtual screening, and molecular dynamics simulation.

Affiliations and Expertise

Teaching Assistant, School of Agricultural Biotechnology, Punjab Agricultural University, India

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