Description

Biofabrication is a practical guide to the novel, inherently cross-disciplinary scientific field that focuses on biomanufacturing processes and a related range of emerging technologies. These processes and technologies ultimately further the development of products that may involve living (cells and/or tissues) and nonliving (bio-supportive proteins, scaffolds) components. The book introduces readers to cell printing, patterning, assembling, 3D scaffold fabrication, cell/tissue-on-chips as a coherent micro-/nano-fabrication toolkit. Real-world examples illustrate how to apply biofabrication techniques in areas such as regenerative medicine, pharmaceuticals and tissue engineering.

In addition to being a vital reference for scientists, engineers and technicians seeking to apply biofabrication techniques, this book also provides an insight into future developments in the field, and potential new applications.

Key Features

Discover the multi-disciplinary toolkit provided by biofabrication and apply it to develop new products, techniques and

therapies.

Covers a range of important emerging technologies in a coherent manner: cell printing, patterning, assembling, 3D

scaffold fabrication, cell/tissue-on-chips...

Readers develop the ability to apply biofabrication technologies through practical examples

Readership

R&D teams, researchers and

scientists in the fields of

Bioengineering / Biomaterials /

Biofabrication / Biomedical

Engineering / Tissue Engineering;

Regenerative Medicine,

Biotechnology, Pharmaceuticals,

Mechanical Engineering.

Engineers and Industrial scientists at

pharmaceutical companies, biotech

companies, medical device

companies.

Biotechnologists and Process

E

Table of Contents

Preface

List of Contributors

Chapter 1. In Vitro Biofabrication of Tissues and Organs

Introduction

1.1 Problems with scaffold-based tissue engineering

1.2 “Scaffold-free” tissue engineering

1.3 Aggregation/spheroid-based approaches

Conclusion

References

Chapter 2. Biomaterials for Biofabrication of 3D Tissue Scaffolds

Introduction

2.1 Materials for 3D tissue scaffolds

2.2 Fabrication methods for 3D tissue scaffolds

2.3 Application of 3D tissue scaffolds

2.4 Future perspectives of biomaterials for 3D scaffolds

Conclusion

Acknowledgment

References

Chapter 3. Projection Printing of Three-Dimensional Tissue Scaffolds with Tunable Poisson’s Ratio

Introduction

3.1 Digital micromirror-assisted projection printing stereolithography

3.2 Negative Poisson’s ratio biomaterials

3.3 Hybrid Poisson’s ratio biomaterial

3.4 Zero Poisson’s ratio biomaterials

Conclusion

References

Chapter 4. Fabrication of Microscale Hydrogels for Tissue Engineering Applications

Introduction

4.1 Technologies for fabrication of microengineered hydrogels

4.2 Tissue engineering applications

Conclusion

Acknowledgments

References

Chapter 5. Polymeric Membranes for the Biofabrication of Tissues and Organs

Introduction

5.1 Properties of polymeric membranes

5.2 Membranes for tissue engineering

5.3 Hollow fiber polymeric membranes for cell and tissue perfusion

5.4 Membrane bioreactors for tissue constructs

5.5 Future perspectives

References

Chapter 6. Laser-Assisted Bioprinting for Tissue Engineering

Introduction

6.1 LAB’s terms of reference

6.2 LAB parameters for cell printing

6.3 High-resolution/high-throughput

Details

No. of pages:
288
Language:
English
Copyright:
© 2013
Published:
Imprint:
William Andrew
Print ISBN:
9781455728527
Electronic ISBN:
9781455730049