Biochemistry of Vision - 1st Edition - ISBN: 9780126400205, 9780323157414

Biochemistry of Vision

1st Edition

Authors: Hitoshi Shichi
eBook ISBN: 9780323157414
Imprint: Academic Press
Published Date: 28th January 1983
Page Count: 290
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Description

Biochemistry of Vision provides information pertinent to vision biochemistry. This book discusses the biochemical information derived primarily from studies on nonocular tissues and describes the biochemical reactions related to the function of the retina and pigmented epithelium. Organized into 16 chapters, this book begins with an overview of the visual system and the structure of the vertebrate eye. The text then proceeds with a discussion of photoreceptor, which has a highly membranous structure. Other chapters cover a brief discussion of several topics, including biomembranes, photochemistry, spectral properties of retinal isomers, and the photochemical properties of the chromophore of rhodopsin. This book discusses as well the properties and intramembrane disposition of rhodopsin. The final chapter deals with the biochemistry of photoreceptor disorders and summarizes the basic knowledge on neurotransmitters and electrophysiology in the retina. This book is intended for ophthalmologists and medical students who are interested in the molecular aspects of photoreceptor diseases.

Table of Contents


Preface

1 Structure of the Eye

I. Transparent Tissues

II. Uvea

III. Retina

IV. Differentiation of Ocular Tissues

References

2 Properties of Biomembranes

I. Lipids

II. Proteins

III. Fluidity

IV. Protein-Protein Interaction

V. Liposomes

References

3 Rod Outer Segment Membranes

I. The Fluid Nature of Rod Membranes

II. Disposition of Rhodopsin in the Membrane

III. Phospholipids of Rod Membranes

References

4 Photochemistry

I. Energy of Photons

II. Spin States of Electrons

III. Electronic Orbitals and Energy States

IV. Photochemical Energy Transfer

V. Absorption Spectrum and Absorption

Parameters

References

5 Structure and Spectral Properties of Retinal Isomers

I. Isomerism

II. Spectroscopy

References

6 Chromophore of Rhodopsin

I. Retinal

II. Spectral Properties of Rhodopsin

References

7 Intermediates Formed by Photobleaching of Visual Pigments

I. Hypsorhodopsin

II. Bathorhodopsin

III. Lumirhodopsin

IV. Metarhodopsins

V. Energetics

VI. lodopsin

References

8 Purification and Properties of Rhodopsin

I. Extraction and Purification of Rhodopsin

II. Preparation of Rod Outer Segments and Rod Disks

III. Chemical Properties of Rhodopsin

IV. Physical Properties

References

9 Metabolism and Functions of Retinol and Its Derivatives

I. Biosynthesis of Retinol

II. Transport of Retinol (Retinol Binding Protein)

III. Retinol Binding Protein within the Cell

IV. Functions of Retinol and Its Derivatives

References

10 Metabolism of the Retina and Pigmented Epithelium

I. Vascular Systems in the Eye

II. Metabolism of the Pigmented Epithelium

III. Metabolism of the Retina

References

11 Bacteriorhodopsin and Halorhodopsin

I. Bacteriorhodopsin

II. Halorhodopsin

III. Evolutionary Significance

References

12 Cell Biology of Photoreceptor Membranes

I. Synthesis and Breakdown of Photoreceptor Membranes

II. Assembly of Cell Membranes

III. Assembly of Disk Membrane

References

13 Cellular Receptors and Signal Transmission

I. General Mechanisms of Signal Transmission

II. Other Mechanisms

References

14 Electrophysiology and Neurotransmitters

I. Basic Aspects

II. Retinal Neurons

III. Neurotransmitters in the Nervous System

IV. Neurotransmitters in the Retina

References

15 Visual Excitation

I. Ca2+ Model

II. Biochemical Model

References

16 Biochemistry of Photoreceptor Disorders

I. Retinitis Pigmentosa

II. Gyrate Atrophy of the Choroid and Retina

III. Uveoretinal Autoimmune Diseases

References

Index

Details

No. of pages:
290
Language:
English
Copyright:
© Academic Press 1983
Published:
Imprint:
Academic Press
eBook ISBN:
9780323157414

About the Author

Hitoshi Shichi

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