Biochemistry of Brain - 1st Edition - ISBN: 9780080213453, 9781483153599

Biochemistry of Brain

1st Edition

Editors: Sudhir Kumar
eBook ISBN: 9781483153599
Imprint: Pergamon
Published Date: 1st January 1980
Page Count: 634
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Biochemistry of Brain is a collection of articles dealing with the developments in the biochemistry of the brain.
This book gives a comprehensive and critical discussion of important developments in studies concerning the above subject. This text discusses the structure, function, and metabolism of glycosphingolipids, which are related to the study of sphingolipid storage diseases. Inborn defects of metabolism are found in Gaucher's and Fabry's disease, which are characterized by lipid accumulation in the brain. Another paper reviews the chemical and genetics of critically lysosomal hydrolase deficiencies that can cause the storage of sphingolipids.
This book then explains the role of myelin basic protein in lipids in vivo that the weak bonding of the protein is not a major component of myelin stability. Another paper discusses the procedures for isolating subfractions of myelin and myelin-related membranes, with some attention given on the alterations in the subfractionation of myelin in pathological hypomyelinating and demyelinating conditions. Another article discusses the biochemical and enzymatic composition of lysosomes and the biosynthesis, intracellular transport, storage, and the degradation of lysosomal constituents.
This collection of papers will benefit scientists doing research in microbiology, microchemistry, molecular genetics, and neurochemistry.

Table of Contents


Structure, Function and Metabolism of Glycosphingolipids

Metabolic Disorders in Sphingolipidoses

Myelin Basic Protein: What Does it Do?

The Biochemical and Morphological Heterogeneity of Myelin and Myelin-Related Membranes

Folate Metabolism in Brain

Vitamin B12 and the Nervous System

Brain Biogenic Amines in Mental Dysfunctions Attributable to Thyroid Hormone Abnormalities

Brain Specific Proteins

Brain Nucleic Acids

Free Nucleotides and Nucleic Acids during Brain Development

Transfer RNAs in Brain

Molecular Biological Aspects of Degeneration of the Nervous

System Caused by Aging and Sensory Deprivation

Nutrition and Amino Acid Imbalance as Factors Influencing Brain Development

Brain Amino Acids

Molecular Neurobiology of Memory

Neural Tissue Culture : a Biochemical Tool

Neurotoxic Effects of Heavy Metals and Metalloid's

Aminotransferases and the Developing Brain

Role of Cyclic AMP in Developing Brain

Protein Phosphorylation—Involvement in Brain Function

Nerve Growth Factor

Brain Lyosomes and Lysosomal Enzymes

Specificity of CNS Myelin Proteolipid Protein and Basic Protein



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About the Editor

Sudhir Kumar

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