Biochemistry of Brain is a collection of articles dealing with the developments in the biochemistry of the brain.
This book gives a comprehensive and critical discussion of important developments in studies concerning the above subject. This text discusses the structure, function, and metabolism of glycosphingolipids, which are related to the study of sphingolipid storage diseases. Inborn defects of metabolism are found in Gaucher's and Fabry's disease, which are characterized by lipid accumulation in the brain. Another paper reviews the chemical and genetics of critically lysosomal hydrolase deficiencies that can cause the storage of sphingolipids.
This book then explains the role of myelin basic protein in lipids in vivo that the weak bonding of the protein is not a major component of myelin stability. Another paper discusses the procedures for isolating subfractions of myelin and myelin-related membranes, with some attention given on the alterations in the subfractionation of myelin in pathological hypomyelinating and demyelinating conditions. Another article discusses the biochemical and enzymatic composition of lysosomes and the biosynthesis, intracellular transport, storage, and the degradation of lysosomal constituents.
This collection of papers will benefit scientists doing research in microbiology, microchemistry, molecular genetics, and neurochemistry.
Structure, Function and Metabolism of Glycosphingolipids
Metabolic Disorders in Sphingolipidoses
Myelin Basic Protein: What Does it Do?
The Biochemical and Morphological Heterogeneity of Myelin and Myelin-Related Membranes
Folate Metabolism in Brain
Vitamin B12 and the Nervous System
Brain Biogenic Amines in Mental Dysfunctions Attributable to Thyroid Hormone Abnormalities
Brain Specific Proteins
Brain Nucleic Acids
Free Nucleotides and Nucleic Acids during Brain Development
Transfer RNAs in Brain
Molecular Biological Aspects of Degeneration of the Nervous
System Caused by Aging and Sensory Deprivation
Nutrition and Amino Acid Imbalance as Factors Influencing Brain Development
Brain Amino Acids
Molecular Neurobiology of Memory
Neural Tissue Culture : a Biochemical Tool
Neurotoxic Effects of Heavy Metals and Metalloid's
Aminotransferases and the Developing Brain
Role of Cyclic AMP in Developing Brain
Protein Phosphorylation—Involvement in Brain Function
Nerve Growth Factor
Brain Lyosomes and Lysosomal Enzymes
Specificity of CNS Myelin Proteolipid Protein and Basic Protein
- No. of pages:
- © Pergamon 1980
- 1st January 1980
- eBook ISBN: