Biochemistry of Brain

Biochemistry of Brain

1st Edition - January 1, 1980

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  • Editor: Sudhir Kumar
  • eBook ISBN: 9781483153599

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Biochemistry of Brain is a collection of articles dealing with the developments in the biochemistry of the brain. This book gives a comprehensive and critical discussion of important developments in studies concerning the above subject. This text discusses the structure, function, and metabolism of glycosphingolipids, which are related to the study of sphingolipid storage diseases. Inborn defects of metabolism are found in Gaucher's and Fabry's disease, which are characterized by lipid accumulation in the brain. Another paper reviews the chemical and genetics of critically lysosomal hydrolase deficiencies that can cause the storage of sphingolipids. This book then explains the role of myelin basic protein in lipids in vivo that the weak bonding of the protein is not a major component of myelin stability. Another paper discusses the procedures for isolating subfractions of myelin and myelin-related membranes, with some attention given on the alterations in the subfractionation of myelin in pathological hypomyelinating and demyelinating conditions. Another article discusses the biochemical and enzymatic composition of lysosomes and the biosynthesis, intracellular transport, storage, and the degradation of lysosomal constituents. This collection of papers will benefit scientists doing research in microbiology, microchemistry, molecular genetics, and neurochemistry.

Table of Contents

  • Preface

    Structure, Function and Metabolism of Glycosphingolipids

    Metabolic Disorders in Sphingolipidoses

    Myelin Basic Protein: What Does it Do?

    The Biochemical and Morphological Heterogeneity of Myelin and Myelin-Related Membranes

    Folate Metabolism in Brain

    Vitamin B12 and the Nervous System

    Brain Biogenic Amines in Mental Dysfunctions Attributable to Thyroid Hormone Abnormalities

    Brain Specific Proteins

    Brain Nucleic Acids

    Free Nucleotides and Nucleic Acids during Brain Development

    Transfer RNAs in Brain

    Molecular Biological Aspects of Degeneration of the Nervous

    System Caused by Aging and Sensory Deprivation

    Nutrition and Amino Acid Imbalance as Factors Influencing Brain Development

    Brain Amino Acids

    Molecular Neurobiology of Memory

    Neural Tissue Culture : a Biochemical Tool

    Neurotoxic Effects of Heavy Metals and Metalloid's

    Aminotransferases and the Developing Brain

    Role of Cyclic AMP in Developing Brain

    Protein Phosphorylation—Involvement in Brain Function

    Nerve Growth Factor

    Brain Lyosomes and Lysosomal Enzymes

    Specificity of CNS Myelin Proteolipid Protein and Basic Protein


Product details

  • No. of pages: 634
  • Language: English
  • Copyright: © Pergamon 1980
  • Published: January 1, 1980
  • Imprint: Pergamon
  • eBook ISBN: 9781483153599

About the Editor

Sudhir Kumar

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