Biochemical and Neurophysiological Correlation of Centrally Acting Drugs - 1st Edition - ISBN: 9780080108049, 9781483185385

Biochemical and Neurophysiological Correlation of Centrally Acting Drugs

1st Edition

Second International Pharmacological Meeting

Editors: E. Trabucchi R. Paoletti N. Canal
eBook ISBN: 9781483185385
Imprint: Pergamon
Published Date: 1st January 1964
Page Count: 296
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Section on Pharmacology of the International Union of Physiological Sciences (SEPHAR), Proceedings of the Second International Pharmacological Meeting, August 20-23, 1963, Volume 2: Biochemical and Neurophysiological Correlation of Centrally Acting Drugs focuses on the composition, reactions, and applications of centrally acting drugs.

The selection first offers information on the physiology of striopallidum in relation to extrapyramidal function and disorders and actions of dopa and dopamine in relation to function of the central nervous system. Discussions focus on correlation of behavioral and clinical states with metabolism of dopamine, functions of dopamine in the brain, and the central pharmacology of dopamine. The text then examines the role of brain dopamine (3-hydroxytyramine) in Parkinsonism, including behavior of dopamine in the extrapyramidal centers in patients with Parkinson's disease; brain dopamine and the extrapyramidal symptomatology of Parkinson's disease; and parallelism between Parkinson's disease and the Parkinson-like state induced by reserpine in man.

The publication ponders on pharmacological studies on tremorine and metabolism of tremorine. The manuscript also takes a look at the contribution on the pathophysiology of intentional tremor; failure of Antiparkinson drugs to antagonize hypothermia in tremorine-treated rats; and significance of dopamine in psychomotor stimulant action.

The selection is a dependable source of data for readers interested in centrally acting drugs.

Table of Contents

List of Authors

Drugs Interfering with the Extrapyramidal System

Physiology of the Striopallidum in Relation to Extrapyramidal Function and Disorders

Actions of DOPA and Dopamine in Relation to Function of the Central Nervous System

Dopamine in the Central Nervous System

The Role of Brain Dopamine (3-Hydroxytyramine) in Parkinsonism

Pharmacological Studies on Tremorine

The Metabolism of Tremorine

Contribution on the Pathophysiology of Intentional Tremor

Médicaments Agissant sur la Symptomatologie Extra-Pyramidale des Neuroleptiques

Failure of Antiparkinson Drugs to Antagonize Hypothermia in Tremorine-Treated Rats

De l'Antagonisme vis-à-vis de Différents Effets de la Trémorine chez la Souris

Significance of Dopamine in Psychomotor Stimulant Action

Discussion to Part I

Drugs Interfering with Thermoregulation

The Physiology and Pharmacology of Temperature Regulation with Particular Reference to the Chemical Mediators

The Physiology of Thermoregulation

An Analysis of Hyperthermia Induced by 5-HTP

Drogues Hypothermisantes

Action des Inhibiteurs de la L-DOPA/5-HTP Décarboxylase en Hypothermie

Pharmacological Studies on the Effect Caused by Pyrogen on Rabbits

Catecholamine-Induced Endotoxin-Like Fever

The Role of Autonomic Nervous Function in Mammalian Thermoregulation

Metabolic Implications of Cold Adaptation

Antagonistes de l'Action Hyperthermisante du Lysergamide chez le Lapin

Neuro-Stimulants Hallucinogènes et Non-Hallucinogènes: Confrontation Expérimentale de leurs Effets sur les Températures Centrale et Periphérique

Discussion to Part II



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About the Editor

E. Trabucchi

R. Paoletti

N. Canal

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