Biochemical and Neurophysiological Correlation of Centrally Acting Drugs

Biochemical and Neurophysiological Correlation of Centrally Acting Drugs

Second International Pharmacological Meeting

1st Edition - January 1, 1964

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  • Editors: E. Trabucchi, R. Paoletti, N. Canal
  • eBook ISBN: 9781483185385

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Section on Pharmacology of the International Union of Physiological Sciences (SEPHAR), Proceedings of the Second International Pharmacological Meeting, August 20-23, 1963, Volume 2: Biochemical and Neurophysiological Correlation of Centrally Acting Drugs focuses on the composition, reactions, and applications of centrally acting drugs. The selection first offers information on the physiology of striopallidum in relation to extrapyramidal function and disorders and actions of dopa and dopamine in relation to function of the central nervous system. Discussions focus on correlation of behavioral and clinical states with metabolism of dopamine, functions of dopamine in the brain, and the central pharmacology of dopamine. The text then examines the role of brain dopamine (3-hydroxytyramine) in Parkinsonism, including behavior of dopamine in the extrapyramidal centers in patients with Parkinson's disease; brain dopamine and the extrapyramidal symptomatology of Parkinson's disease; and parallelism between Parkinson's disease and the Parkinson-like state induced by reserpine in man. The publication ponders on pharmacological studies on tremorine and metabolism of tremorine. The manuscript also takes a look at the contribution on the pathophysiology of intentional tremor; failure of Antiparkinson drugs to antagonize hypothermia in tremorine-treated rats; and significance of dopamine in psychomotor stimulant action. The selection is a dependable source of data for readers interested in centrally acting drugs.

Table of Contents

  • List of Authors

    Drugs Interfering with the Extrapyramidal System

    Physiology of the Striopallidum in Relation to Extrapyramidal Function and Disorders

    Actions of DOPA and Dopamine in Relation to Function of the Central Nervous System

    Dopamine in the Central Nervous System

    The Role of Brain Dopamine (3-Hydroxytyramine) in Parkinsonism

    Pharmacological Studies on Tremorine

    The Metabolism of Tremorine

    Contribution on the Pathophysiology of Intentional Tremor

    Médicaments Agissant sur la Symptomatologie Extra-Pyramidale des Neuroleptiques

    Failure of Antiparkinson Drugs to Antagonize Hypothermia in Tremorine-Treated Rats

    De l'Antagonisme vis-à-vis de Différents Effets de la Trémorine chez la Souris

    Significance of Dopamine in Psychomotor Stimulant Action

    Discussion to Part I

    Drugs Interfering with Thermoregulation

    The Physiology and Pharmacology of Temperature Regulation with Particular Reference to the Chemical Mediators

    The Physiology of Thermoregulation

    An Analysis of Hyperthermia Induced by 5-HTP

    Drogues Hypothermisantes

    Action des Inhibiteurs de la L-DOPA/5-HTP Décarboxylase en Hypothermie

    Pharmacological Studies on the Effect Caused by Pyrogen on Rabbits

    Catecholamine-Induced Endotoxin-Like Fever

    The Role of Autonomic Nervous Function in Mammalian Thermoregulation

    Metabolic Implications of Cold Adaptation

    Antagonistes de l'Action Hyperthermisante du Lysergamide chez le Lapin

    Neuro-Stimulants Hallucinogènes et Non-Hallucinogènes: Confrontation Expérimentale de leurs Effets sur les Températures Centrale et Periphérique

    Discussion to Part II


Product details

  • No. of pages: 296
  • Language: English
  • Copyright: © Pergamon 1964
  • Published: January 1, 1964
  • Imprint: Pergamon
  • eBook ISBN: 9781483185385

About the Editors

E. Trabucchi

R. Paoletti

N. Canal

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