Biocatalysis in Green Solvents

Biocatalysis in Green Solvents

1st Edition - September 1, 2022

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  • Editor: Pedro Lozano
  • Paperback ISBN: 9780323913065

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Biocatalysis in Green Solvents offers a pragmatic overview and instruction in biocatalysis and enzymology of green solvents for sustainable industries and medicine, running from concept to application. Here, international experts in the field discuss structure-function relationships of enzymes in ionic liquids (ILs) and examine how enzymes act as selective catalysts for fine biochemical synthesis in non-aqueous environments. Several integral green biochemical processes of biocatalytic transformation and pure product separation are described in detail. Application focused chapters discuss the role of biocatalysis in creating and implementing deep eutectic solvents, biomass derived solvents, sub and supercritical fluids, carbon dioxide biphasic systems, and enzymatic membrane reactors, as well as applying these biocatalytic processes in drug discovery and production.

Key Features

  • Examines the structure-function relationships of enzymes in ionic liquids and biocatalytic processes for various applications across industry and medicine
  • Includes clear instruction in core green biochemical processes—of (bio)catalytic transformation—and pure product separation
  • Features chapter contributions from international experts across academia and industry


Basic and translational researchers in biochemistry, biotechnology, molecular biology, cellular biology, biomaterials and engineering, chemical biology, and sustainability science, life science researchers, bioengineers, clinicians and graduate students in the biosciences

Table of Contents

  • 1. Preface
    Prof. Pedro Lozano
    2. Foreword
    Prof. Jairton Dupont
    3. Non-conventional biocatalysis: From organic solvents to Green Solvents
    Susana Nieto and Pedro Lozano
    4. Synthesis and characterization of Ionic Liquids
    Thomas Schubert
    5. Biocatalysis and Green Metrics in Sustainable Chemistry
    Prof. Roger A. Sheldon
    6. Ionic liquids in biocatalytic organic synthesis
    Prof. Toshiyuki Itoh
    7. Ionic liquids in protein refolding
    Pannuru Venkatesu
    8. Stability and Stabilization of biocatalyst by ILs
    Prof. Hua Zhao
    9. Improved Biocatalysts for Green processes
    Prof. Roberto Fernandez-Lafuente
    10. Clean Biocatalysis in Sponge-Like Ionic Liquids
    Prof. Antonio Donaire and Prof. Pedro Lozano
    11. Oxidoreductases in ionic liquids and Deep eutectic Solvents (DESs) for organic chemistry
    Prof. Vicente Gotor-Fernandez
    12. Potential roles for ionic liquid assisted biocatalysis in a low carbon future
    Andrew C. Marr, Queens Univ Belfast, UK
    13. Biocatalysis in ABS systems based on ILs
    Pro. Joao A. P. Coutinho
    14. Biotransformations of carbohydrates in ILs
    Prof. Maria J. Hernaiz
    15. Biocatalysis in biomass derived solvents
    Pablo Dominguez de Maria
    16. Ionic liquids for biomass biotransformations
    Eric Husson and Catherine Sarazin
    17. Biocatalysis in sub and supercritical fluids
    Zeljko Knez
    18. Supported ionic liquids for biocatalysis
    Eduardo Garcia-Verdugo and Santiago V. Luis
    19. Biocatalytic processes in ionic liquids/supercritical carbon dioxide biphasic systems
    Rovio Villa and Pedro Lozano
    20. Enzymatic membrane reactors and non-conventional solvents
    Jose Sánchez and Marie Pierre Belleville
    21. Ionic Liquids for Biopolymer Extraction and Processing
    Muhammad Moniruzzaman
    22. Application of Ionic Liquids in Pharmaceutics and Medicine
    23. Industrial application of Ionic Liquids
    Thomas Schubert

Product details

  • No. of pages: 472
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: September 1, 2022
  • Imprint: Academic Press
  • Paperback ISBN: 9780323913065

About the Editor

Pedro Lozano

Dr. Pedro Lozano is a Professor of Biochemistry and Molecular Biology at the University of Murcia in Murcia, Spain. Born in Ceuti, Spain in 1961, Prof. Lozano received his PhD at the University of Murcia in 1988. Between 1990 and 1991, he spent two years at the Centre de Bioingénierie Gilbert Durand, Toulouse (France) as a post-doctoral fellow. In 1993, he returned to the University of Murcia (Spain) as Lecturer in Biochemistry and Molecular Biology, later being promoted to Full Professor in 2004. His research activity has always been related to enzyme technology in ionic liquids and supercritical fluids. In 2002, he published a paper on the first continuous green biocatalytic reactor, based on the combination of enzymes with ILs and scCO2 able to directly provide pure products.

Affiliations and Expertise

Professor of Biochemistry and Molecular Biology, University of Murcia in Murcia, Murcia, Murcia, Spain

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