Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease provides valuable insights for those seeking nutritional treatment options for those suffering from liver and/or related gastrointestinal disease including Crohn’s, allergies, and colitis among others. Information is presented on a variety of foods including herbs, fruits, soy and olive oil. This book serves as a valuable resource for researchers in nutrition, nephrology, and gastroenterology.

Key Features

  • Addresses the most positive results from dietary interventions using bioactive foods to impact diseases of the liver and gastrointestinal system, including reduction of inflammation, improved function, and nutritional efficiency
  • Presents a wide range of liver and gastrointestinal diseases and provides important information for additional research
  • Associated information can be used to understand other diseases, which share common etiological pathways


Nutritionists, dieticians, and biomedical researchers who focus on identifying the causes of gastrointestinal and related liver diseases; food scientists targeting health-related product development

Table of Contents

Acknowledgments for Bioactive Foods in Chronic Disease States

Preface: Liver and Gastrointestinal Health


Chapter 1. The Alkaline Way in Digestive Health

1 Dietary Factors in Metabolism

2 Glycemic Load as a Tool for Better Digestive and Cardiovascular Management

3 Native Whey-Based Meals and Gastrointestinal Health

4 Food Allergies and Sensitivities

5 The Role of Specific Nutrients in Digestive Health

6 Conclusion


Relevant Websites

Chapter 2. Functional Assessment of Gastrointestinal Health

1 Physiology of Digestion

2 Clinical Issues in Digestive Health

3 Systemic Influences on GI Health


Relevant Websites

Chapter 3. Antioxidants in Inflammatory Bowel Disease, Ulcerative Colitis, and Crohn Disease

1 The Pathogenesis of Ulcerative Colitis and Crohn Disease

2 ROS in UC and CD

3 Oxidants and Antioxidants in the Experimental Colitis

4 Antioxidanta in Human IBD


Chapter 4. Omega-6 and Omega-3 Polyunsaturated Fatty Acids and Inflammatory Bowel Diseases


1 Introduction

2 PUFAs: Structure, Nomenclature, Sources, and Interconversion

3 Intake of n-6 and n-3 PUFAs and Risk of Developing IBD

4 Lipid Mediators: Biosynthesis, Roles in IBD, and the Impact of n-3 PUFAs

5 Influence of Marine n-3 Fatty Acids on Inflammatory Cytokines

6 Influence of Marine n-3 Fatty Acids on T Cells

7 Efficacy of n-3 PUFAs in Animal Models of IBD

8 Human Studies of Marine n-3 PUFAs in IBD

9 Conclusions


Chapter 5. Alcohol and Gastrointestinal Tract Function

1 Acute and Chronic Ingestion of Alcohol

2 Absorption of Alcohol

3 Alcohol Consumption and GI Tract

4 Consequences of Alcohol Abuse

5 Effect of Alcohol on Im


No. of pages:
© 2013
Academic Press
eBook ISBN:
Print ISBN:

About the editors

Ronald Ross Watson

Ronald R. Watson, Ph.D., attended the University of Idaho but graduated from Brigham Young University in Provo, Utah, with a degree in chemistry in 1966. He earned his Ph.D. in biochemistry from Michigan State University in 1971. His postdoctoral schooling in nutrition and microbiology was completed at the Harvard School of Public Health, where he gained 2 years of postdoctoral research experience in immunology and nutrition. From 1973 to 1974 Dr. Watson was assistant professor of immunology and performed research at the University of Mississippi Medical Center in Jackson. He was assistant professor of microbiology and immunology at the Indiana University Medical School from 1974 to 1978 and associate professor at Purdue University in the Department of Food and Nutrition from 1978 to 1982. In 1982 Dr. Watson joined the faculty at the University of Arizona Health Sciences Center in the Department of Family and Community Medicine of the School of Medicine. He is currently professor of health promotion sciences in the Mel and Enid Zuckerman Arizona College of Public Health. Dr. Watson is a member of several national and international nutrition, immunology, cancer, and alcoholism research societies. Among his patents he has one on a dietary supplement; passion fruit peel extract with more pending. He continues to do research in animals and in clinical trials on dietary supplements and health including studies using omega-3 fatty acids in heart disease prevention and therapy. For 30 years he was funded by Wallace Research Foundation to study dietary supplements in health promotion. Dr. Watson has edited more than 110 books on nutrition, dietary supplements and over-the-counter agents, and drugs of abuse as scientific reference books. He has published more than 500 research and review articles.

Affiliations and Expertise

Mel and Enid Zuckerman College of Public Health, and School of Medicine, University of Arizona, Tucson, AZ, USA

Victor Preedy

Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC is a senior member of King's College London. He is also Director of the Genomics Centre and a member of the Faculty of Life Sciences and Medicine. Professor Preedy has longstanding academic interests in substance misuse especially in relation to health and well being. He is a member of the Editorial Board of Drug and Alcohol Dependence and a founding member of the Editorial Board of Addiction Biology. In his career Professor Preedy was Reader at the Addictive Behaviour Centre at The University of Roehampton, and also Reader at the School of Pharmacy (now part of University College London; UCL). Professor Preedy is Editor of the influential works The Handbook Of Alcohol Related Pathology, The Neuropathology of Drug Addictions and Substance Misuse and The Handbook of Cannabis and Related Pathologies (all published by Academic Press-Elsevier). Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctoral degree (DSc). Professor Preedy was elected as a Fellow of the Institute of Biology in 1995 and also as a Fellow to the Royal College of Pathologists in 2000. He was then elected as a Fellow of the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health and Hygiene (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.

Affiliations and Expertise

Department of Dietetics, King's College London, UK