One major example of the synergy of bioactive foods and extracts is their role as an antioxidant and the related remediation of cardiovascular disease. There is compelling evidence to suggest that oxidative stress is implicated in the physiology of several major cardiovascular diseases including heart failure and increased free radical formation and reduced antioxidant defences. Studies indicate bioactive foods reduce the incidence of these conditions, suggestive of a potential cardioprotective role of antioxidant nutrients.

Bioactive Food as Dietary Interventions for Cardiovascular Disease investigates the role of foods, herbs and novel extracts in moderating the pathology leading to cardiovascular disease. It reviews existing literature, and presents new hypotheses and conclusions on the effects of different bioactive components of the diet.

Key Features

  • Addresses the most positive results from dietary interventions using bioactive foods to impact cardiovascular disease
  • Documents foods that can affect metabolic syndrome and other related conditions
  • Convenient, efficient and effective source that allows readers to identify potential uses of compounds – or indicate those compounds whose use may be of little or no health benefit
  • Associated information can be used to understand other diseases that share common etiological pathways


Nutritionists, dieticians, and biomedical researchers whose focus is on identifying cardiovascular and related diseases; food scientists targeting health-related product development.

Table of Contents

Acknowledgments for Bioactive Foods in Chronic Disease States

Preface: Bioactive Food for Cardiovascular Disease


Chapter 1. Omega-3 Fatty Acids in Prevention of Cardiovascular Disease in Humans: Intervention Trials, Healthy Heart Concept, Future Developments

1 Introduction

2 Role of Omega-3 Fatty Acids in CVD

3 Modern View of Omega Fatty Acid Therapy in CVD

4 Healthy Heart Concept: Less-Known Facts on Omega Fatty Acids

5 Guidelines on Omega Fatty Acid in CVD to Physicians, Nurses: Healthy Heart Concept

6 Implications and Futuristic Prospective

7 Conclusions



Chapter 2. Herbal Supplements or Herbs in Heart Disease: History, Herbal Foods, Coronary Heart Disease

1 Introduction

2 Relation to TG Metabolism

3 Herbal Foods: Approved Herbs in Cardiovascular Disease

4 Repertory of Herbs and Their Properties

5 Herbs in Human Use

6 Cardioprotective Herb Active Components in Human Use Approved by CDC and Regulated by FDA

7 Conclusion



Chapter 3. Plant Statins and Heart Failure

1 Heart Failure

2 Statins in the Treatment of HF

3 Complementary Medicine in Heart Failure

4 Plant Sterols/Stanols (Phytosterols)

5 Conclusion


Chapter 4. Bioactive Nutrients and Cardiovascular Disease

1 Bioactive Nutrients


Chapter 5. Vitamins and Myocardial Infarction in Diabetics


1 Introduction

2 Patients with Myocardial Infarction and DM Are at Particular Risk

3 Importance of OS in Myocardial Infarction

4 Importance of OS in DM

5 Antioxidant Effect of Vitamins

6 Summary


Chapter 6. Cardioprotective Nutrients

1 Introduction

2 Cardioprotective Nutr


No. of pages:
© 2013
Academic Press
eBook ISBN:
Print ISBN:

About the editors

Ronald Ross Watson

Ronald R. Watson, Ph.D., attended the University of Idaho but graduated from Brigham Young University in Provo, Utah, with a degree in chemistry in 1966. He earned his Ph.D. in biochemistry from Michigan State University in 1971. His postdoctoral schooling in nutrition and microbiology was completed at the Harvard School of Public Health, where he gained 2 years of postdoctoral research experience in immunology and nutrition. From 1973 to 1974 Dr. Watson was assistant professor of immunology and performed research at the University of Mississippi Medical Center in Jackson. He was assistant professor of microbiology and immunology at the Indiana University Medical School from 1974 to 1978 and associate professor at Purdue University in the Department of Food and Nutrition from 1978 to 1982. In 1982 Dr. Watson joined the faculty at the University of Arizona Health Sciences Center in the Department of Family and Community Medicine of the School of Medicine. He is currently professor of health promotion sciences in the Mel and Enid Zuckerman Arizona College of Public Health. Dr. Watson is a member of several national and international nutrition, immunology, cancer, and alcoholism research societies. Among his patents he has one on a dietary supplement; passion fruit peel extract with more pending. He continues to do research in animals and in clinical trials on dietary supplements and health including studies using omega-3 fatty acids in heart disease prevention and therapy. For 30 years he was funded by Wallace Research Foundation to study dietary supplements in health promotion. Dr. Watson has edited more than 110 books on nutrition, dietary supplements and over-the-counter agents, and drugs of abuse as scientific reference books. He has published more than 500 research and review articles.

Affiliations and Expertise

Mel and Enid Zuckerman College of Public Health, and School of Medicine, University of Arizona, Tucson, AZ, USA

Victor Preedy

Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC is a senior member of King's College London. He is also Director of the Genomics Centre and a member of the Faculty of Life Sciences and Medicine. Professor Preedy has longstanding academic interests in substance misuse especially in relation to health and well being. He is a member of the Editorial Board of Drug and Alcohol Dependence and a founding member of the Editorial Board of Addiction Biology. In his career Professor Preedy was Reader at the Addictive Behaviour Centre at The University of Roehampton, and also Reader at the School of Pharmacy (now part of University College London; UCL). Professor Preedy is Editor of the influential works The Handbook Of Alcohol Related Pathology, The Neuropathology of Drug Addictions and Substance Misuse and The Handbook of Cannabis and Related Pathologies (all published by Academic Press-Elsevier). Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctoral degree (DSc). Professor Preedy was elected as a Fellow of the Institute of Biology in 1995 and also as a Fellow to the Royal College of Pathologists in 2000. He was then elected as a Fellow of the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health and Hygiene (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.

Affiliations and Expertise

Department of Dietetics, King's College London, UK