Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases

1st Edition

Bioactive Food in Chronic Disease States

Editors: Ronald Ross Watson Victor Preedy
Hardcover ISBN: 9780123971562
eBook ISBN: 9780123977656
Imprint: Academic Press
Published Date: 22nd October 2012
Page Count: 680
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While diet has long been recognized as having potential to alleviate symptoms of inflammatory diseases including arthritis, lupus and fibromyalgia, research indicates that specific foods offer particular benefits in preventing or mitigating specific symptoms. Bioactive Food as Dietary Interventions for Arthritis and Inflammatory Diseases is the only available resource focused on exploring the latest advances in bioactive food research written for the scientist or professional audience.

Key Features

  • The only single-volume resource for scientists and professionals seeking information on how bioactive foods may assist in the treatment of inflammatory disease
  • Includes coverage of probiotics, prebiotics, and polyphenols
  • Convenient, efficient and effective source that allows reader to identify potential uses of compounds – or indicate those compounds whose use may in fact be of little or no health benefit
  • Documents foods that can affect inflammatory disease and ways the associated information could be used to understand other diseases, which share common etiological pathways


Nutritionists, dieticians, and biomedical researchers who study the effects of bioactive foods on arthritis and other inflammatory diseases; food scientists targeting health-related product development.

Table of Contents

Preface: Arthritis and Inflammation


Chapter 1. Antioxidant Flavonoids for Arthritis Treatment: Human and Animal Models


1 Introduction to Phytoflavonoids

2 What Is Arthritis?

3 Osteoarthritis

4 Rheumatoid Arthritis

5 Flavonoids

6 Animal Models of Acute and Chronic Inflammation

7 Flavonoids and Its Effect on Animal Model Arthritis

8 Radiographic Analysis of Adjuvant-Induced Arthritis

9 Flavonoids Devoid of Toxic Effects

10 Clinical Trial of Flavonoids on Arthritis

11 The Mechanism of Actions of Flavonoids



Chapter 2. Inflammation in Arthritis


1 Introduction

2 Mechanism of Inflammation in Arthritis

3 Dairy Products and Inflammation

4 Effects of Food and Spices in Inflammation

5 The Role of PUFA in Arthritis

6 Antioxidants and Inflammation in Arthritis

7 Summary


Chapter 3. Effects of Beef on Inflammation Affecting Arthritis


1 Introduction

2 Arthritis and Diet

3 Contraindications of Beef

4 Dietary Recommendations of Beef

5 Conclusions



Further Reading

Chapter 4. Contribution of Bioactive Foods and Their Emerging Role in Immunomodulation, Inflammation, and Arthritis


1 Bioactive Food Components

2 Immunomodulation

3 Arthritis

4 Inflammation


Chapter 5. Curcumin and Joint Health: From Traditional Knowledge to Clinical Validation


1 Introduction

2 Clinical Relevance of Osteoarthritis

3 Prevalence and Causes of OA

4 Current OA Treatments

5 Preclinical and Clinical Evidence of Activity for Curcumin in the Treatment of OA

6 The


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About the Editor

Ronald Ross Watson

Ronald Ross Watson PhD is a professor of Health Promotion Sciences in the University of Arizona Mel and Enid Zuckerman College of Public Health. He was one of the founding members of this school serving the mountain west of the USA. He is a professor of Family and Community Medicine in the School of Medicine at the University of Arizona. He began his research in public health at the Harvard School of Public Health as a fellow in 1971 doing field work on vaccines in Saudi Arabia. He has done clinical studies in Colombia, Iran, Egypt, Saudi Arabia, and USA which provides a broad international view of public health. He has served in the military reserve hospital for 17 years with extensive training in medical responses to disasters as the chief biochemistry officer of a general hospital, retiring at a Lt. Colonel. He published 450 papers, and presently directs or has directed several NIH funded biomedical grants relating to alcohol and disease particularly immune function and cardiovascular effects including studying complementary and alternative medicines. Professor Ronald Ross Watson was Director of a National Institutes of Health funded Alcohol Research Center for 5 years. The main goal of the Center was to understand the role of ethanol-induced immunosuppression on immune function and disease resistance in animals. He is an internationally recognized alcohol-researcher, nutritionist and immunologist. He also initiated and directed other NIH-associated work at The University of Arizona, College of Medicine. Dr. Watson has funding from companies and non-profit foundations to study bioactive foods’ components in health promotion. Professor Watson attended the University of Idaho, but graduated from Brigham Young University in Provo, Utah, with a degree in Chemistry in 1966. He completed his Ph.D. degree in 1971 in Biochemistry from Michigan State University. His postdoctoral schooling was completed at the Harvard School of Public Health in Nutrition and Micro

Affiliations and Expertise

Mel and Enid Zuckerman College of Public Health, School of Medicine, University of Arizona, Tucson, AZ, USA

Victor Preedy

Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC is a senior member of King's College London. He is also Director of the Genomics Centre and a member of the Faculty of Life Sciences and Medicine. Professor Preedy has longstanding academic interests in substance misuse especially in relation to health and well being. He is a member of the Editorial Board of Drug and Alcohol Dependence and a founding member of the Editorial Board of Addiction Biology. In his career Professor Preedy was Reader at the Addictive Behaviour Centre at The University of Roehampton, and also Reader at the School of Pharmacy (now part of University College London; UCL). Professor Preedy is Editor of the influential works The Handbook Of Alcohol Related Pathology, The Neuropathology of Drug Addictions and Substance Misuse and The Handbook of Cannabis and Related Pathologies (all published by Academic Press-Elsevier). Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctoral degree (DSc). Professor Preedy was elected as a Fellow of the Institute of Biology in 1995 and also as a Fellow to the Royal College of Pathologists in 2000. He was then elected as a Fellow of the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health and Hygiene (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.

Affiliations and Expertise

Department of Dietetics, King's College London, UK