
Basic Principles of Drug Discovery and Development
Resources
Description
Key Features
- Provides a clear explanation of how the pharmaceutical industry works, as well as the complete drug discovery and development process, from obtaining a lead, to testing the bioactivity, to producing the drug, and protecting the intellectual property
- Includes a new chapter on the discovery and development of biologics (antibodies proteins, antibody/receptor complexes, antibody drug conjugates), a growing and important area of the pharmaceutical industry landscape
- Features a new section on formulations, including a discussion of IV formulations suitable for human clinical trials, as well as the application of nanotechnology and the use of transdermal patch technology for drug delivery
- Updated chapter with new case studies includes additional modern examples of drug discovery through high through-put screening, fragment-based drug design, and computational chemistry
Readership
Upper level undergraduate students and graduate students interested in drug discovery research, chemistry, biology, pharmacology, biochemistry, toxicology, formulations, discovery/development of new therapeutic agents; pharmaceutical industry; FDA, public policy groups interested in influencing the pharmaceuticals industry; business analysts, entrepreneurs, venture capitalists interested in investing in the pharmaceuticals industry
Table of Contents
1. Drug Discovery and Development: An Overview of Modern Methods and Principles
2. The Drug Discovery Process: From Ancient Times to the Present Day
3. Classical Targets in Drug Discovery
4. In Vitro Screening Systems
5. Medicinal Chemistry
6. In vitro ADME and In vivo Pharmacokinetics
7. Animal Models of Disease States
8. Safety and Toxicology
9. Antibody Drug Discovery
10. Basics of Clinical Trials
11. Translational Medicine and Biomarkers
12. Organizational Considerations and Trends in the Pharmaceutical Industry
13. Intellectual Property and Patents in Drug Discovery
14. Case Studies in Drug Discovery
Product details
- No. of pages: 712
- Language: English
- Copyright: © Academic Press 2021
- Published: March 30, 2021
- Imprint: Academic Press
- eBook ISBN: 9780128172155
- Paperback ISBN: 9780128172148
About the Author
Benjamin Blass
Affiliations and Expertise
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