Basic Principles in Nucleic Acid Chemistry V1

List of Contributors

Preface

Contents of Other Volumes


1. In the Beginning

I. The Beginning of the Scientific Investigation of Nucleic Acid

II. The Beginning of the Formation of Nucleic Acid as Genetic Material and its Progressive Change Reflected in the Evolution of the Biological Kingdom

III. The Beginning of the Influence of Nucleic Acid Research on the Future of Man—"Intelligent" Evolution

References


2. Chemical Syntheses and Transformations of Nucleosides

I. Introduction

II. Synthesis of Nucleosides

III. Chemical Transformation of the Sugar Moieties of Nucleosides

IV. Chemical Transformations of the Heterocyclic Base Moieties of Nucleosides

V. Chemical Transformations That Involve both the Sugar and the Heterocyclic Base


3. Mass Spectrometry

I. Introduction

II. Production of Mass Spectra

III. Mass Spectra of Purine and Pyrimidine Bases

IV. Nucleosides and their Derivatives

V. Applications of Mass Spectrometry to Nucleotides

VI. Experimental Note

References


4. Excited States of Nucleic Acids

I. Introduction

II. Summary of Molecular Electronic Excited States

III. Excited States of Nucleotides

IV. Luminescence of Nucleotides as a Probe: The Y Base in tRNA

V. Interacting Chromophores

VI. Excited Polynucleotides

VII. Excited State Precursors for Photoproducts

References


5. Infrared and Raman Spectroscopy

I. Introduction

II. Vibrations in Nucleic Acids

III. Infrared Spectra of Nucleic Acids

IV. Raman Spectra of Nucleic Acids

References


6. Bases, Nucleosides, and Nucleotides

I. Structure, Configuration, Conformation, and Other Intrinsic Properties

II. Interaction of the Monomers

References

Author Index

Subject Index