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Basic Pharmacology - 2nd Edition - ISBN: 9780407004160, 9781483142098

Basic Pharmacology

2nd Edition

Editor: R W Foster
eBook ISBN: 9781483142098
Imprint: Butterworth-Heinemann
Published Date: 19th September 1986
Page Count: 408
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Basic Pharmacology, Second Edition, similar to the first edition, talks about the relationship between the human body and therapeutic drugs. A large part of this book discusses the nervous system and the way certain drugs operate and affect it. The first part of this book covers the importance of having a firm understanding of the organ system, especially the nervous system. Understanding the systems is the initial step in learning how a drug affects the body, both internally and externally. This book also clarifies that a drug's impact occurs when it comes in contact with a chemical component of the body (enzymes, hormones, membranes, etc.). The next sections of this book discuss miscellaneous topics of the human anatomy, such as the brain, eyes, lungs, and various muscles. This edition also explains how a drug acts on each of those body parts. This book serves as a great reference to students affiliated in the anatomy, biology, pharmacy, and related fields.

Table of Contents

1 Drug Action on Peripheral Excitable Tissues-Drugs Related to the Neurotransmitters Acetylcholine and Noradrenaline

Anatomy and Physiology of the (Efferent) Peripheral Nervous System and Its Effectors

The Effector Cells Innervated by Postganglionic Autonomic Neurones: Important Effects Caused by Nervous Activity

The Pharmacology of Cholinergic Axons and Their Terminals

The Pharmacology of the Cholinoceptors of Skeletal Muscle

The Pharmacology of the Cholinoceptors of Ganglia

The Pharmacology of the Cholinoceptors of Smooth Muscle, Cardiac Muscle and Exocrine Glands

Cholinesterases and Their Inhibitors

The Pharmacology of Noradrenergic Neuroeffector Transmission

The Adrenal Medulla

2 Drug Action on Peripheral Tissues-Drugs Unrelated to Neurotransmitters or Hormones

Local Anesthesia

Cardiac Antidysrhythmic Drugs

Cardiac Glycosides

Calcium Channel Blockers




Anticoagulant, Antithrombotic and Fibrinolytic Compounds

3 Endocrine Pharmacology

Hypothalamo-Pituitary Axis


Oestrogens, Progestogens and Androgens

The Thyroid Gland and Drugs Used in Thyroid Abnormalities

The Adrenal Cortex and the Corticosteroids

Insulin and Glucagon

Posterior Pituitary Hormones


Local Hormones

The Pharmacology of Inflammation

4 Drug Action on the Central Nervous System

Chemical Transmission in the CNS

Some Disorders of Movement

Classification of Mental Disorders


Antipsychotic Drugs

Vomiting, Emetics and Antiemetics

Opioid Analgesics and Their Antagonists

Stimulants and Hallucinogens

Antipyretic Analgesics

The State of Consciousness and the Nonspecific Depressants

5 Antiparasitic Chemotherapy

Biochemical Selectivity

Distributional Selectivity

Chemotherapy of Metazoal Infestations

Chemotherapy of Protozoal Infections

Chemotherapy of Fungal Infections

Chemotherapy of Bacterial Infections

Chemotherapy of Viral Infections

Chemotherapy of Malignant Neoplasms

6 Drug Disposition and Metabolism





Drug Dosage Regimens

Physicochemical Groupings

Water-Soluble Drugs

Drugs with Intermediate Solubility

Lipid-Soluble Drugs

Acidic Drugs

Basic Drugs

7 Applied Pharmacology

Acute Poisoning

Gastrointestinal Complaints

Congestive Heart Failure

Hypertension and Antihypertensive Drugs

Angina of Effort


Coughs and Colds

Headache and Migraine

Mental Disorders and Drugs That Alleviate Them


Family Planning

Drugs and the Cellular Elements of Blood

Drugs in Joint Disease

Drugs and the Skin

8 General Pharmacology

Mechanisms of Drug Action

Adverse Effects of Drugs

Adverse Drug Interactions

Abuse of Drugs

Drug Design, Development and Testing

Suggested Further Reading



No. of pages:
© Butterworth-Heinemann 1986
19th September 1986
eBook ISBN:

About the Editor

R W Foster

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