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Goodman's Basic Medical Endocrinology
5th Edition - February 21, 2021
Authors: Elizabeth H. Holt, Beatrice Lupsa, Grace S. Lee, Hanan Bassyouni, Harry E. Peery
Language: English
Hardback ISBN:9780128158449
9 7 8 - 0 - 1 2 - 8 1 5 8 4 4 - 9
eBook ISBN:9780128158456
9 7 8 - 0 - 1 2 - 8 1 5 8 4 5 - 6
Goodman's Basic Medical Endocrinology, Fifth Edition, has been student tested and approved for decades. This essential textbook provides up-to-date coverage of rapidly unfolding…Read more
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Goodman's Basic Medical Endocrinology, Fifth Edition, has been student tested and approved for decades. This essential textbook provides up-to-date coverage of rapidly unfolding advances in the understanding of hormones involved in regulating most aspects of bodily functions. It is richly illustrated in full color with both descriptive schematic diagrams and laboratory findings obtained in clinical studies. This is a classic reference for moving forward into advanced study.
Clinical case studies in every chapter
E-book version available with every copy for obtaining images and tables for lectures or notes
Clinicians added as co-authors to enhance usefulness by physicians and medical students and residents
Detailed molecular biology of hormones and hormone action for graduate and advanced undergraduate students
Expanded and updated color images emphasizing hormone action at the molecular level
In-depth molecular biology and clinical sections boxed for ease of access
Cover image
Title page
Table of Contents
Copyright
Dedications
Preface
Any screen. Any time. Anywhere
Chapter 1. Introduction
Abstract
Types of chemical messengers
Storage and release of hormones
Hormone transportation and fate
Hormone specificity
Hormone receptors
Desensitization and downregulation of G-protein-coupled receptors
Negative feedback
Positive feedback
Feed forward
Immunoassays
Radioimmunoassay
Immunometric assays
Suggested reading
Chapter 2. Pituitary gland
Abstract
Pituitary gland
Chapter 3. Thyroid gland
Abstract
Introduction
Morphology
Thyroid hormones
Control of thyroid function
Thyroid hormones in blood
Metabolism of thyroid hormones
Physiological effects of thyroid hormones
Regulation of thyroid hormone secretion
Mechanism of thyroid hormone action
Summary
Suggested readings
Chapter 4. The adrenal glands
Abstract
Adrenal glands
Anatomy and histology
Adrenal cortex
Physiology of the mineralocorticoids
Physiology of the glucocorticoids
Adrenal medulla
Suggested readings
Chapter 5. Principles of hormone integration
Abstract
Introduction
Integration of hormonal signals at the cellular and molecular level
Modulation of responding systems
Hormonal integration at the whole-body level
Summary
Suggested readings
Chapter 6. Hormones of the gastrointestinal tract
Abstract
Gastrointestinal hormones
Concluding comments
Suggested readings
Chapter 7. The pancreatic islets
Abstract
The pancreatic islets
Morphology of the endocrine pancreas
Glucagon
Insulin
Somatostatin
Summary
Suggested readings
Chapter 8. Hormonal regulation of fuel metabolism
Abstract
Hormonal regulation of fuel metabolism
General features of energy metabolism
Overall regulation of blood glucose concentration
Integrated actions of metabolic hormones
Regulation of metabolism during feeding and fasting
Hormonal interactions during exercise
Long-term regulation of fuel storage
Peripheral input to hypothalamic feeding and satiety neurons
Summary
Suggested readings
Chapter 9. Regulation of salt and water balance
Abstract
Introduction
Suggested reading
Chapter 10. Hormonal regulation of calcium balance
Abstract
Hormonal regulation of calcium balance
General features of calcium balance
Parathyroid glands and parathyroid hormone
Mechanisms of parathyroid hormone actions
Physiological actions of parathyroid hormone
Calcitonin
Vitamin D hormone
Calcium regulation of plasma calcium concentrations
Integrated actions of calciotropic hormones
Other hormones that influence calcium balance
Summary
References
Suggested readings
Chapter 11. Hormonal control of growth
Abstract
Hormonal control of growth
Effect of thyroid hormone on growth
Effect of insulin on growth
Effect of gonadal hormones on growth
Effect of glucocorticoids on growth
Summary
Suggested reading
Additional information
Chapter 12. Hormonal control of reproduction in the male
Abstract
Introduction
Sexual differentiation
Testes
Testosterone
Male reproductive development
Regulation of testicular function II
Summary
Oxytocin in the male
Suggested reading
Chapter 13. Hormonal control of reproduction in the female: the menstrual cycle
Abstract
Hormonal control of reproduction in the female: the menstrual cycle
Ovarian hormones
Control of ovarian function
Physiological actions of ovarian steroid hormones
Regulation of the reproductive cycle
Timing of reproductive cycles
Summary
Suggested readings
Chapter 14. Hormonal control of pregnancy and lactation
Abstract
Hormonal control of pregnancy and lactation
Fertilization and implantation
Respiratory adjustments
Summary
Suggested readings
Index
No. of pages: 552
Language: English
Edition: 5
Published: February 21, 2021
Imprint: Elsevier
Hardback ISBN: 9780128158449
eBook ISBN: 9780128158456
EH
Elizabeth H. Holt
Dr. Holt is the co-director of the Yale Endocrine Neoplasia Group; past president of the Connecticut Endocrine Society; and has been recognized many times as a top doctor by Connecticut magazine.
Affiliations and expertise
Associate Professor of Medicine, Endocrinology, Yale School of Medicine, New Haven, CT, United States
BL
Beatrice Lupsa
Dr. Beatrice Lupsa is an Endocrinologist at Yale University School of Medicine in New Haven, Connecticut. She has a large academic clinical practice at the Yale Diabetes Center. Her clinical and academic interests include type 1 and type 2 diabetes mellitus, cardiovascular complications of diabetes, extreme forms of insulin resistance and lipodystrophy. Dr. Lupsa has expertise in continuous glucose monitoring systems, insulin pumps and in managing complicated diabetes cases. She is a dedicated clinician-educator training residents and fellows. She has authored many articles and book chapters and has been an invited reviewer for several endocrinology journals.
Affiliations and expertise
Assistant Professor of Medicine, Endocrinology, Yale School of Medicine, New Haven, CT, United States
GL
Grace S. Lee
Dr. Grace S. Lee is Assistant Professor of Medicine, Endocrinology, at the Yale School of Medicine in New Haven, CT, United States. Dr. Lee received her undergraduate B.S. degree from UCLA in Los Angeles, CA and her M.D. degree from New York University School of Medicine in New York, NY. She completed her internship and residency in Internal Medicine as well as her fellowship in Endocrinology and Metabolism at Yale-New Haven Hospital in New Haven, CT. Dr. Lee has a clinical practice that treats patients with metabolic bone disease, thyroid nodules, thyroid cancer, adrenal disease, pituitary disease, and diabetes mellitus.
Affiliations and expertise
Assistant Professor of Medicine, Endocrinology, Yale School of Medicine, New Haven, CT, United States; Endocrinologist, VA CT Healthcare System, West Haven, CT, United States
HB
Hanan Bassyouni
Dr. Bassyouni is heavily involved in the education of trainees at different levels of UME and PGME at the Cumming School of Medicine, the University of Calgary. She is a member of the endocrinology division which spans six medical sites across Calgary with a team of 25 members who provide their expert service in the Diabetes Center, the David Hanley Osteoporosis center, the multidisciplinary thyroid cancer and thyroid nodule clinic, the endocrine hypertension clinic, the Diabetes in Pregnancy program, the Neuroendocrine clinic and in general Endocrinology clinics. Dr. Bassyouni provides out reach endocrinology consultant service to several clinics serving underprivileged and marginalized populations.
Affiliations and expertise
Clinical Associate Professor, Cumming School of Medicine, Faculty of Medicine, Department of Medicine, Section of Endocrinology and Metabolism, University of Calgary, Calgary, AB, Canada
HP
Harry E. Peery
Dr. Peery is a professor who has taught medical and graduate students at the Cumming School of Medicine at the University of Calgary as well as at professional schools in other universities in the United States and Canada. In addition, he is an Affiliate Assistant Professor in the Department of Bioengineering at the School of Medicine at the University of Washington, Seattle. He received his Bachelor of Science degree from Syracuse University, his MSc from Ohio State University, and his PhD from the University of Saskatchewan. At the University of Calgary, he is a member of the Department of Biochemistry and Molecular Biology and is an Associate Member of the Arnie Charbonneau Cancer Research Institute. He currently works in the lab of Dr. Karl Riabowol in the Cumming School of Medicine where he focuses his research on the pathogenesis of anti-NMDA receptor encephalitis, cancer biomarkers, and glioblastoma. He is one of the founding directors of The Anti-NMDA Receptor Encephalitis Foundation, Inc., headquartered in Ottawa, Ontario, Canada.
Affiliations and expertise
Professor, Department of Cell Biology and Anatomy, and Arnie Charbonneau Cancer Research Institute, Laboratory of Dr. Karl Riabowol, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada
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