Description

This book brings together the most important research developments of the past 45 years that have enriched our knowledge and contributed to a better understanding of the biochemistry and cell and molecular biology of basement membranes. It describes the studies that shed light on the ultrastructural organization, the biosynthesis of the macromolecular components, their functions in embryonic development and differentiation, and in the mature state. A major portion of the book is devoted to the description of the genes that regulate the expression of the various structural macromolecules.

Key Features

* Reviews the early years of research and the discovery of type IV collagen * Presents the diversity of basement membrane morphology * Discusses gene structure

Readership

Researchers in cell biology, developmental biology, biochemistry, bioengineering, genetics, immunology, immunochemistry, neuroscience, diabetes, nephrology, embyrology, vascular surgery, cardiology, rheumatology, hematology, bone and joint surgery, cancer research, and angiogenesis.

Details

No. of pages:
448
Language:
English
Copyright:
© 2005
Published:
Imprint:
Academic Press
Print ISBN:
9780121533564
Electronic ISBN:
9780080917214

About the editors

Nicholas Kefalides

Affiliations and Expertise

Professor of Medicine-Emeritus, Professor of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA, U.S.A.