Volume 96. Bacterial Infections of the Central Nervous System

1st Edition

Handbook of Clinical Neurology (Series Editors: Aminoff, Boller and Swaab)


  • Karen Roos
  • Allan Tunkel
  • Bacterial Infections of the Central Nervous System

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    Bacterial Infections of the Central Nervous System aims to provide information useful to physicians taking care of patients with bacterial infections in the central nervous system (CNS), which can lead to morbidity and mortality. The increased number of patients suffering from this infection has led to the development of vaccines and antibiotics. Comprised of four chapters, the book explains the general approach to patients with bacterial CNS infection. It also discusses various CNS infection concepts and terms. These include the characteristic neuroimaging appearance of specific bacterial infections, the limitations of neuroimaging, the cerebrospinal fluid analysis, the pathogenesis and pathophysiology of bacterial CNS infections, the developments of specific adjunctive strategies, and the principles of antimicrobial therapy. It also includes discussions on various diseases that target the CNS, such as meningitis, focal CNS infections, neurological complications of endocarditis, suppurative venous sinus thrombosis, infections in the neurosurgical patient, and CNS diseases caused by selected infectious agents and toxins. This book will serve as a guide for clinical physicians who have patients suffering from bacterial CNS infection.

    Key Features

    * Valuable insights into the pathophysiological mechanism of bacterial CNS infections
    * A multidisciplinary reach that provides critical information for neurologists, neurosurgeons, and specialists in infectious disease
    * Considerable information and emphasis on new diagnostic techniques and laboratory testing



    Neuroscience research workers

    Table of Contents

    Foreword Preface List of contributors 1. Pathogenesis and pathophysiology of bacterial CNS infections 2. Principles of antimicrobial therapy 3. Lumbar puncture and cerebrospinal fluid analysis 4. Bacterial meningitis 5. Brain abscess 6. Cranial epidural abscess and subdural empyema 7. Spinal epidural abscess and subdural empyema 8. Suppurative intracranial thrombophlebitis 9. Infections of the central nervous system in the neurosurgical patient 10. Rickettsial and ehrlichial infections 11. Mycobacterial infections 12. Spirochetal infections 13. Neurological complications of bacterial endocarditis 14. Whipple’s disease of the central nervous system 15. Neuroimaging of central nervous system infections 16. Toxin-mediated syndromes of the nervous system Index


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    © 2010
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    Electronic ISBN:

    About the editors

    Karen Roos

    Affiliations and Expertise

    Indiana University School of Medicine, Indianapolis, IN, USA John and Nancy Nelson Professor of Neurology

    Allan Tunkel

    Affiliations and Expertise

    Chair, Department of Medicine, Monmouth Medical Center, Long Branch, NJ, USA