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Initiation of Autophagy by Photodynamic Therapy Nancy L. Oleinick and David Kessel
Autophagic cell death Michael Lenardo and Li Yu
Autophagic neuron death Yasuo Uchiyama, Masato Koike, Masahiro Shibata, and Mizuho Sasaki
Assessing Metabolic Stress and Autophagy Status in Epithelial Tumors Robin Mathew, Vassiliki Karantza-Wadsworth and Eileen White
Autophagic clearance of aggregate–prone proteins associated with neurodegeneration Sovan Sarkar, Brinda Ravikumar and David Rubinsztein
- Monitoring Autophagy in Alzheimer's Disease and Related Neurodegenerative Diseases Sovan Dun-Sheng Yang, Ju-Hyun Lee; Ralph A. Nixon
Live-cell imaging of autophagy induction and autophagosome-lysosome fusion in primary cultured neurons Mona Bains and Kim A. Heidenreich
Using Genetic Mouse Models to Study the Biology and Pathology of Autophagy in the Central Nervous System Zhenyu Yue*, Gay R. Holstein, Brian T. Chait and Qing Jun Wang
Biochemical and Morphological Detection of Inclusion Bodies in Autophagy-deficient Mice Masaaki Komatsu and Satoshi Waguri
Analyzing Autophagy in Clinical Tissues of Lung and Vascular Diseases Augustine Choi, Zhi Hua Chen, Hong Pyo Kim and Stefan Ryter
Autophagy in Neurite Injury and Neurodegeneration: in vitro and in vivo models Charleen T. Chu, Edward D. Plowey, Robert W. Hickey, Ruben K. Dagda and Robert S.B. Clark
MONITORING THE AUTOPHAGY PATHWAY IN CANCER John L. Cleveland, Frank Dorsey and Meredith Steeves
Autophagy pathways in glioblastoma Hong Jiang, Erin White, Charles Conrad, Candelaria Gomez-Manzano and Juan Fueyo
Autophagy in Lung Cancer Bo Lu
Signal-dependent control of autophagy-related gene expression Fulvio Chiacchiera and Cristiano Simone
Novel Methods for Measuring Cardiac Autophagy in vivo Roberta A. Gottlieb and Junichi Sadoshima
Autophagy in Load-Induced Heart Disease Hongxin Zhu, Beverly A. Rothermel and Joseph A. Hill
EVALUATION OF CELL DEATH MARKERS IN SEVERE CALCIFIED AORTIC VALVES Wilhelm P. Mistiaen and Michiel W.M. Knaapen
Monitoring autophagy in muscle diseases Ichizo Nishino, May Malicdan and Satoru Noguchi
Analyzing Macroautophagy in Hepatocytes and the Liver Xiao-Ming Yin
Monitoring Autophagy in Lysosomal Storage Disorders Nina Raben, Victoria Hill, Lauren Shea and Paul Plotz
The third and final installment of Daniel J. Klionsky's new three-volume treatment of autophagy, this volume focuses on monitoring autophagy with regard to disease connections, and presents methods that can be used to analyze autophagy in clinical samples. Edited by one of the leading authorities in the field, this volume and its companion volumes, Autophagy: Lower Eukaryotes and Autophagy in Mammalian Systems, provide a comprehensive overview of the techniques involved in studying autophagy in eukaryotes and simple animal systems, mammalian cells and non-human animals, and humans.
Particularly in times of stress, like starvation and disease, higher organisms have an internal mechanism in their cells for chewing up and recycling parts of themselves. The process of internal “house cleaning” in the cell is called autophagy – literally self-eating. In the future, research in this field will help to design clinical approaches that can turn on autophagy and halt tumor growth.
- Provides an overview of autophagy in regards to humans, specifically regarding disease connections and clinical samples.
- Includes methods to evaluate the role of autophagy in the drug-induced cell death of cancer cells in culture
- Presents reliable methods that, in this relatively new field, allow the reader to find appropriate techniques to identify, monitor, and quantify autophagic processes
Researchers and students in biochemistry, cell and molecular biology, oncology, pharmacology
- No. of pages:
- © Academic Press 2009
- 11th February 2009
- Academic Press
- Hardcover ISBN:
- eBook ISBN:
Life Sciences Institute, University of Michigan, USA
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