Autonomic Dysfunction in Parkinson's Disease

Autonomic Dysfunction in Parkinson's Disease

1st Edition - September 24, 2021

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  • Editors: Cristian Falup-Pecurariu, Peter Jenner
  • Paperback ISBN: 9780323851220
  • eBook ISBN: 9780323851237

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Autonomic dysfunction is one of the most prevalent non-motor symptoms that occurs in Parkinson’s disease. Autonomic Dysfunction in Parkinson's Disease provides up to date information on this important topic, which affects quality of life of these patients. This include a large number of domains: orthostatic hypotension, excessive sweating, dry eyes, constipation, weight loss, increased sensitivity to heat and cold, sexual dysfunction.

Key Features

  • Provides comprehensive reviews on different topics of autonomic dysfunction in Parkinson’s disease
  • Each chapter covers a specific autonomic symptom: classification, assessment, treatment
  • Presents the newest information on each autonomic symptom in Parkinson’s disease


General neurologists, movement disorders specialists, cardiologists, geriatricians, urologists, gynecologists

Table of Contents

  • Preface
    Cristian Falup-Pecurariu
    1. Autonomic nervous system-Anatomy, physiology, and biochemistry
    Iva Stanković, Ivan Adamec, Vladimir Kostić and Mario Habek
    2. General approach to patients with autonomic dysfunction in Parkinson’s disease
    Valentina Leta, Vanessa Raeder and K Ray Chaudhuri
    3. Rating scales for dysautonomia in Parkinson’s disease
    Ștefania Diaconu, Laura Irincu, Irina Ivan and Cristian Falup-Pecurariu
    4. Assessing autonomic dysfunction with functional imaging in Parkinson's disease
    Jacob Horsager,Casper Skjærbæk and Per Borghammer
    5. Cardiovascular autonomic failure in Parkinson's disease
    Fabian Leys, Gregor K. Wenning and Alessandra Fanciulli
    6. Drooling and dysphagia in Parkinson's disease
    Mauricio Paez Maggio, Santiago Perez Lloret and Marcelo Merello
    7. Gastrointestinal dysfunction in Parkinson's disease
    Jonathan Timpka and Per Odin
    8. Urinary dysfunction in Parkinson's disease
    Roongroj Bhidayasiri,Warongporn Phuenpathom and Yoshio Tsuboi
    9. Autonomic dysfunction during sleep in Parkinson's disease
    Francesca Baschieri, Pietro Guaraldi, Pietro Cortelli and Giovanna Calandra-Buonaura
    10. Thermoregulatory dysfunctions in idiopathic Parkinson’s disease
    Brim, Bianca and Struhal, Walter

Product details

  • No. of pages: 314
  • Language: English
  • Copyright: © Academic Press 2021
  • Published: September 24, 2021
  • Imprint: Academic Press
  • Paperback ISBN: 9780323851220
  • eBook ISBN: 9780323851237

About the Editors

Cristian Falup-Pecurariu

Cristian Falup-Pecurariu
Cristian Falup-Pecurariu is Head of the Department of Neurology, County Clinic Hospital from Brasov, and is Associate Professor of Neurology at the Faculty of Medicine, Transilvania University from Brasov, Romania. He received his medical degree from the University of Medicine and Pharmacy “Iuliu Hatieganu” from Cluj-Napoca. He hold a 1 year fellowship of the European Neurological Society in movement disorders and sleep medicine at Hospital Clinic, University of Barcelona, Spain. During his career Cristian Falup-Pecurariu was President of the European Association of Young Neurologists and Trainees (EAYNT), EAYNT Liasion Officer with World Federation of Neurological Society, co-representative of Europe on the International Working Group for Young Neurologists and Trainees (World Federation of Neurology). He was also Secretary of the EFNS/MDS-ES Panel on Movement Disorders, member of the Educational Committee of MDS-ES, member of the MDS Leadership Task Force and European Academy of Neurology Scientific Panel Movement Disorders. Cristian Falup-Pecurariu is also member of the Teaching Course sub-Committee of the European Academy of Neurology (EAN), Member of the EAN Scientific Panel Movement disorders Management Group. Currently he is Chair of the Education Committee of the International Parkinson and Movement Disorders Society (MDS) – European Section, member of the Executive Committee of MDS-European Section, member of the International Executive Committee of MDS, Chair of the Archives Committee MDS, Member of the Rating Scales Executive Committee of MDS, co-Chair of the Rating Scales Education and Training Program Committee of MDS. Cristian Falup-Pecurariu is member of EUROPAR (European Parkinson’s Group), member in Steering Committee of the International Parkinson and Movement Disorders Society Non motor study group. He is the initiator and Course Director of the Movement Disorders Teaching Course held in Brasov (9 editions). His research focuses on non-motor aspects of Parkinson’s diseases and restless legs syndrome.

Affiliations and Expertise

Chair, Department of Neurology, County Emergency Clinic Hospital, Associate Professor of Neurology, Faculty of Medicine, Transilvania University, Brasov, Romania

Peter Jenner

Professor Peter Jenner is a specialist in preclinical aspects of neurodegenerative diseases, notably Parkinson’s disease. He has spent the major part of his career at King’s College London where he was Head of Pharmacology for 14 years before returning to his research roots and subsequently becoming Emeritus Professor of Pharmacology. Peter has expertise in drug metabolism and pharmacokinetics but neuropharmacology based on functional models of neurodegenerative diseases has formed the major focus of his work. Peter holds a BPharm, PhD and DSc degree from the University of London. He has published well over 1000 articles with more than 700 peer reviewed papers. He is a Fellow of the Royal Pharmaceutical Society, the British Pharmacological Society, the Royal Society of Medicine and of King’s College London. Peter was recently honoured with a Doctor Honoris Causa degree from Carol Davila University of Medicine and Pharmacy, Bucharest and made an Honorary Fellow of The British Pharmacological Society for his contribution to research in to movement disorders. Peter has worked closely with the pharmaceutical industry for many years and acts as an adviser and consultant to both major pharma and biotech companies. He has a wide knowledge of the drug discovery and drug development process and has been involved from molecule synthesis through to drug registration for use in man. Peter was the Founder, Director and Chief Scientific Officer of Proximagen, a biotech focussed on the treatment and cure of neurodegenerative diseases that was listed on AIMs and subsequently purchased by a US based healthcare company. He is a regular speaker at international meetings and also takes time to speak at Parkinson’s disease patient-carer groups across the UK.

Affiliations and Expertise

Emeritus Professor of Pharmacology, Institute of Pharmaceutical Sciences, King’s College London, London, UK

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