Aulton's Pharmaceutics

From a review of the previous edition:

‘For all the pharmacy students out there part of your pharmacy degree will be to study formulation design and pharmaceutics. This is the holy grail of pharmaceutical technology books. The text reads well and introduces difficult concepts in a more easy-to-understand way, it is definitely worth the money to help you get through the module, if you’re doing a research project in pharmaceutical design then this would also be an excellent buy…This is essential for passing exams and developing professional competence.’

This is the best known text on pharmaceutics. Its strength lies mainly in being a complete course in one book. Reviewers consistently praise its comprehensiveness and its extremely high quality-quality content. Pharmaceutics is one of the most diverse subject areas in pharmaceutical science and an understanding of it is vital for all pharmacists and scientists involved in converting drugs to medicines that can be safely delivered to a patient. The editorial and author team deliver a tour de force of accessibility, coverage and currency in this new edition of a world-class textbook.

• Relevant chemistry covered throughout
• Reflects current and future use of biotechnology products throughout
• Covers ongoing changes in our understanding of biopharmaceutics, certain areas of drug delivery and the significance of the solid state
• Includes the science of formulation and drug delivery
• Designed and written for newcomers to the design of dosage forms
• Key points boxes throughout
• Summaries at the end of each chapter

What is pharmaceutics?

1. Design of dosage forms

PART 1 Scientific principles of dosage form design

2. Dissolution and solubility
3. Properties of solutions
4. Surfaces and interfaces
5. Disperse systems
6. Rheology
7. Kinetics

PART 2 Particle science and powder technology

8. Solid-state properties
9. Particle size analysis
10. Particle size reduction and size separation
11. Mixing
12. Powder flow

PART 3 Pharmaceutical microbiology and serialization

13. Fundamentals of microbiology
14. Pharmaceutical applications of microbiological techniques
15. Action of physical and chemical agents on microorganisms
16. Principles of sterilization
17. Sterilization in practice

PART 4 Biopharmaceutical principles of drug delivery

18. Introduction to biopharmaceutics
19. Gastrointestinal tract – physiology and drug absorption
20. Bioavailability – physicochemical and dosage form factors
21. Assessment of biopharmaceutical properties
22. Dosage regimens

PART 5 Dosage form design and manufacture

23. Pharmaceutical preformulation
24. Solutions
25. Clarification
26. Suspensions
27. Emulsions and creams
28. Powders, granules and granulation
29. Drying
30. Tablets and compaction
31. Modified-release oral drug delivery
32. Coating of tablets and multiparticulates
33. Hard capsules
34. Soft capsules
35. Dissolution testing of solid dosage forms
36. Parenteral drug delivery
37. Pulmonary drug delivery
38. Nasal drug delivery
39. Ophthalmic drug delivery
40. Topical and transdermal drug delivery
41. Rectal and vaginal drug delivery
42. The formulation and manufacture of plant medicines
43. Delivery of biopharmaceuticals
44. Pharmaceutical nanotechnology and nanomedicines
45. Design and administration of medicines for children and the elderly

Part 6 Packaging and stability of pharmaceutical products

46. Packaging
47. Chemical stability in dosage forms
48. Microbial contamination, spoilage and preservation of medicines
49. Product stability and stability testing

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