Aulton's Pharmaceutics - 5th Edition - ISBN: 9780702070051, 9780702070013

Aulton's Pharmaceutics

5th Edition

The Design and Manufacture of Medicines

Editors: Kevin Taylor Michael Aulton
Paperback ISBN: 9780702070051
Paperback ISBN: 9780702070037
eBook ISBN: 9780702070013
eBook ISBN: 9780702070020
Imprint: Elsevier
Published Date: 30th June 2017
Page Count: 936

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From a review of the previous edition:

‘For all the pharmacy students out there part of your pharmacy degree will be to study formulation design and pharmaceutics. This is the holy grail of pharmaceutical technology books. The text reads well and introduces difficult concepts in a more easy-to-understand way, it is definitely worth the money to help you get through the module, if you’re doing a research project in pharmaceutical design then this would also be an excellent buy…This is essential for passing exams and developing professional competence.’

This is the best known text on pharmaceutics. Its strength lies mainly in being a complete course in one book. Reviewers consistently praise its comprehensiveness and its extremely high quality-quality content. Pharmaceutics is one of the most diverse subject areas in pharmaceutical science and an understanding of it is vital for all pharmacists and scientists involved in converting drugs to medicines that can be safely delivered to a patient. The editorial and author team deliver a tour de force of accessibility, coverage and currency in this new edition of a world-class textbook.

Key Features

  • Relevant chemistry covered throughout
  • Reflects current and future use of biotechnology products throughout
  • Covers ongoing changes in our understanding of biopharmaceutics, certain areas of drug delivery and the significance of the solid state
  • Includes the science of formulation and drug delivery
  • Designed and written for newcomers to the design of dosage forms
  • Key points boxes throughout
  • Summaries at the end of each chapter

Table of Contents

What is pharmaceutics?

  1. Design of dosage forms
  2. PART 1 Scientific principles of dosage form design

  3. Dissolution and solubility
  4. Properties of solutions
  5. Surfaces and interfaces
  6. Disperse systems
  7. Rheology
  8. Kinetics
  9. PART 2 Particle science and powder technology

  10. Solid-state properties
  11. Particle size analysis
  12. Particle size reduction and size separation
  13. Mixing
  14. Powder flow
  15. PART 3 Pharmaceutical microbiology and serialization

  16. Fundamentals of microbiology
  17. Pharmaceutical applications of microbiological techniques
  18. Action of physical and chemical agents on microorganisms
  19. Principles of sterilization
  20. Sterilization in practice
  21. PART 4 Biopharmaceutical principles of drug delivery

  22. Introduction to biopharmaceutics
  23. Gastrointestinal tract – physiology and drug absorption
  24. Bioavailability – physicochemical and dosage form factors
  25. Assessment of biopharmaceutical properties
  26. Dosage regimens
  27. PART 5 Dosage form design and manufacture

  28. Pharmaceutical preformulation
  29. Solutions
  30. Clarification
  31. Suspensions
  32. Emulsions and creams
  33. Powders, granules and granulation
  34. Drying
  35. Tablets and compaction
  36. Modified-release oral drug delivery
  37. Coating of tablets and multiparticulates
  38. Hard capsules
  39. Soft capsules
  40. Dissolution testing of solid dosage forms
  41. Parenteral drug delivery
  42. Pulmonary drug delivery
  43. Nasal drug delivery
  44. Ophthalmic drug delivery
  45. Topical and transdermal drug delivery
  46. Rectal and vaginal drug delivery
  47. The formulation and manufacture of plant medicines
  48. Delivery of biopharmaceuticals
  49. Pharmaceutical nanotechnology and nanomedicines
  50. Design and administration of medicines for children and the elderly
  51. Part 6 Packaging and stability of pharmaceutical products

  52. Packaging
  53. Chemical stability in dosage forms
  54. Microbial contamination, spoilage and preservation of medicines
  55. Product stability and stability testing

Online self assessment


No. of pages:
© Elsevier 2018
30th June 2017
Paperback ISBN:
Paperback ISBN:
eBook ISBN:
eBook ISBN:

About the Editors

Kevin Taylor

Affiliations and Expertise

Professor of Clinical Pharmaceutics, UCL School of Pharmacy, London, UK

Michael Aulton

Affiliations and Expertise

Emeritus Professor, De Montfort University, Leicester, UK