Atopic Dermatitis: Inside Out or Outside In

Atopic Dermatitis: Inside Out or Outside In

1st Edition - January 14, 2022

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  • Editors: Lawrence S Chan, Vivian Shi
  • Hardcover ISBN: 9780323847445

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Atopic dermatitis (eczema) is one of the most common and most challenging skin conditions, for patients and practitioners alike. Uniquely organized by intrinsic and extrinsic etiologies, Atopic Dermatitis: Inside Out or Outside In? examines a myriad of causes that start from both the inside of the body and from the external environment, offering physicians practical ways to design treatments that specifically address these causes. Drs. Lawrence S. Chan and Vivian Y. Shi, along with a team of expert contributing authors, examine the etiology of this complex disorder and provide targeted, comprehensive solutions and the most useful therapeutic plans based on pathophysiology, including evidence-based integrative management.

Table of Contents

  • Preface
    1 Historic Perspective
    2 Atopy Redefined
    3 Atopy of the Skin
    4 Epidemiology
    5 Skin Barrier
    6 Skin and Gut Microbiome
    7 Immunogens
    8 Nutrition
    9 Oxidative Stress, Environmental factors, Pollutants
    10 Clinical Evidence: External Factors
    11 Keratinocytes
    12 Microvasculature
    13 Humoral Factors
    14 Cellular Factors
    15 Skin-Gut-Lung Epithelial Permeability
    16 Neurosensory Mechanisms
    17 Epigenetics
    18 Clinical Evidence: Internal Factors
    19 Therapeutic Guideline Overview
    20 Topical Therapies
    21 Wound care
    22 Skin barrier Repair
    23 Emerging Targeted Treatments
    24 Microbiome Modulation
    25 Itch and Pain Treatments
    26 Complementary and Alternative Approaches 1
    27 Complementary and Alternative Approaches 2
     End Matter

Product details

  • No. of pages: 336
  • Language: English
  • Copyright: © Elsevier 2022
  • Published: January 14, 2022
  • Imprint: Elsevier
  • Hardcover ISBN: 9780323847445

About the Editors

Lawrence S Chan

Affiliations and Expertise

Dr. Orville J Stone Endowed Professor, Department of Dermatology, University of Illinois at Chicago, Chicago, Captain James Lovel Federal Health Care Centre, North Chicago, IL, USA

Vivian Shi

Dr. Vivian Shi is the Director of Clinical Trials and the Eczema Specialty Clinic at the University of Arkansas for Medical Sciences. Her research and clinical interests are in complex inflammatory skin conditions, skin barrier repair, transepidermal drug delivery, and integrative dermatology. She was an integral part of the team of researchers characterizing the pathophysiology of atopic dermatitis using a transgenic interleukin-4 mouse model of atopic dermatitis. She has published over 150 peer-reviewed articles, and is on the speaker’s bureau and the steering committee for the U.S. National Eczema Association and is a faculty member of the International Eczema Council. She has served as the principal investigator for numerous industry-sponsored and investigator-initiated clinical and translational studies in eczematous conditions. She regularly speaks in national and international conferences on atopic dermatitis and inflammatory skin conditions. Additionally, she is the recipient of the several prestigious awards and grants.

Affiliations and Expertise

Associate Professor, Department of Dermatology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, U.S.A.

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