Atlas of Zebrafish Development

1st Edition

Authors: Robert Bryson-Richardson Silke Berger Peter Currie
Hardcover ISBN: 9780123740168
eBook ISBN: 9780080920610
Imprint: Academic Press
Published Date: 21st September 2011
Page Count: 238
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Description

Zebrafish are widely considered an excellent model system for vertebrate development. The embryo is transparent, thereby enabling visualization and use of labelling and transgenic approaches. Moreover, because of the ease of inducing new mutations in zebrafish and similarity with the human genome, this organism may be used effectively for disease studies. For example, mutant zebrafish are being utilized for testing drugs that will combat a range of human diseases, from Alzheimer's and cancer to kidney failure and congenital heart disease. For the first time, this atlas provides the research community with a complete reference for zebrafish anatomy spanning the early embryo all the way to adulthood.

The authors employ the technique of optical projection tomography (OPT), and offer a series of sections in multiple planes from each sample. The contents are organized by developmental stages, with over 200 images that contain annotations describing anatomical structures relevant to development. In addition, chapters feature explanatory text that highlights major developments in the zebrafish during each stage.

Key Features

  • Provides the first comprehensive anatomical resource that covers all regions of zebrafish anatomy from the larval period to adulthood
  • The over 200 images include explanatory notes
  • Each chapter contains a concise description of key anatomical features that factor in zebrafish development
  • Despite many years of use as a model system, until now there has never been a guide to zebrafish at the larval stage
  • The book's website contains a database of over 10k sections from different regions as well as 3D images that are interactive

Readership

This Atlas will be an essential reference for researchers in a range of disciplines, both academic and commercial, working with zebrafish as a model system for development and/or human disease. It will also be useful as a resource for students in developmental biology, molecular genetics, toxicology, anatomical physiology, embryology, etc.

Table of Contents

Chapter 1. Introduction

Chapter 2. Methodology and Interpretation of the Atlas

Chapter 3. FishNet

Chapter 4. 24 Hours

Chapter 5. 48 Hours

Chapter 6. 72 Hours

Chapter 7. 96 Hours

Chapter 8. 120 Hours

Chapter 9. 6 MM

Chapter 10. 9 MM

Chapter 11. 14 MM

Chapter 12. 16 MM

References

Index

Details

No. of pages:
238
Language:
English
Copyright:
© Academic Press 2012
Published:
Imprint:
Academic Press
eBook ISBN:
9780080920610
Hardcover ISBN:
9780123740168
Paperback ISBN:
9780128103456

About the Author

Robert Bryson-Richardson

Silke Berger

Peter Currie