Atlas of the Ultrastructure of Diseased Human Muscle

Atlas of the Ultrastructure of Diseased Human Muscle

1st Edition - January 1, 1972

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  • Authors: W G P Mair, F M S Tomé
  • eBook ISBN: 9781483280998

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Atlas of the Ultrastructure of Diseased Human Muscle provides a general view of the ultrastructure of normal and diseased human muscle. This book contains five chapters that illustrate the changes that take place in common pathological conditions and outline the patterns of change, which occur in particular diseases. Chapter 1 describes the ultrastructure of normal striated muscle and the extra-ocular and cardiac muscle. This chapter also deals with skeletal and cardiac muscle of the human fetus. Chapter 2 examines the changes in the ultrastructure of muscle fibers, including changes in myofibrils, mitochondria, lipid bodies, plasma, and basement membranes. Chapters 3 and 4 evaluate the changes in blood capillaries, interstitial tissue of muscle, nerves, motor end plates, and muscle spindles. Chapter 5 discusses the ultrastructural changes in various muscle diseases, such as denervation atrophy of muscle, muscular dystrophies, polymyositis, and congenital myopathies.

Table of Contents

  • Foreword


    Chapter I Normal Striated Muscle

    Skeletal Muscle Fibers

    Plasma and Basement Membranes

    Satellite Cells

    Types of Muscle Fibers

    Blood Capillaries, Fibroblasts and Collagen

    Myotendinous Junction

    Nerves and Motor End Plates

    Muscle Spindles

    Extra-ocular Muscle

    Foetal Skeletal Muscle

    Cardiac Muscle. Adult and Foetal


    2 Changes in Muscle Fibers


    Nuclei and Golgi Apparatus



    Lipid Bodies

    Sarcoplasmic Reticulum and T-system (Honeycomb Structures)

    Vacuoles. Autophagic Vacuoles

    Myelin and Membranous Bodies

    Concentric Laminated Bodies

    Tubular Structures

    Crystals and Virus-Like Particles

    Plasma and Basement Membranes

    Satellite Cells and Regeneration of Muscle


    3 Changes in Blood Capillaries and Intestinal Tissue of Muscle

    Blood Capillaries

    Leucocytic Infiltration and Phagocytosis of the Muscle Fibers

    Fibroblasts and Collagen

    Amyloid Fibrils


    4 Changes in Nerves, Motor End Plates and Muscle Spindles

    Changes in Nerves

    Changes in Motor End Plates

    Changes in Muscle Spindles


    5 Changes in Various Muscle Diseases

    Denervation Atrophy of Muscle

    Muscular Dystrophies

    Polymyositis and Allied Conditions

    Metabolic, Endocrine and Toxic Myopathies

    Congenital Myopathies




Product details

  • No. of pages: 250
  • Language: English
  • Copyright: © Elsevier 1972
  • Published: January 1, 1972
  • Imprint: Elsevier
  • eBook ISBN: 9781483280998

About the Authors

W G P Mair

F M S Tomé

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